scholarly journals HPV associated oral lesions among HIV/AIDS patients - a cross sectional study

2014 ◽  
Vol 14 (S3) ◽  
Author(s):  
T Smitha ◽  
CV Mohan
2019 ◽  
Author(s):  
Demelash Wachamo ◽  
Fisseha Bonja

Abstract Background Opportunistic infections are late complications of HIV infection is the depletion of the immune system. It is a major public health problem and high morbidity AIDS patients die of AIDS-related infections in developing countries like Ethiopia. Identification of opportunistic infections (OIs) is important to develop a specific intervention. Therefore, this study aimed to assess the burden and associated factors of opportunistic infections.Method A facility-based cross-sectional study was conducted on 420 randomly selected HIV/AIDS patients taking anti-retroviral therapy. Data was collected from selected hospitals in Sidama Zone based on population proportion to size. Data was collected by a pre-tested questionnaire and a pre-tested checklist from the medical records of patients. Data entry and analyzed for descriptive and logistic regression models by SPSS v.23. The result declared as statistically significant at p < 0.05.Result The magnitude of opportunistic infections was 39.6%. Major identified OIs was oral candidacies 23.2%, recurrent bacterial pneumonia 21.5%, Herpes zoster 6.3%, and Pulmonary Tuberculosis 6.0%.The magnitude of opportunistic associated with; older age [AOR=2.69, 95% CI: 1.33-5.43], No formal education [AOR=3.12, 95% CI: 1.06-9.25], Low monthly income [AOR=2.27, 95%CI:1.35-3.83], initial CD4 count less than 200 cells/mm3 [AOR=1.91, 95% CI:1.05-3.46), WHO clinical stage II [AOR=2.43, 95% CI:1.34-4.42] and stage III and IV [AOR=4.27, 95% CI: 2.12-8.59], had no extra medicine additional to ART (prophylaxis) had [AOR= 5.91, 95% CI: 3.31-10.56], who interrupt ART medicines [AOR=2.03, 95% CI: 1.09- 3.80] and Khat chewing [AOR=5.48, 95% CI: 2.32-12.96] when compared to their counterparts.Conclusions The overall magnitude of opportunistic infections was high when compared with other studies. Health officials and clinicians need to give attention on the strengthening of the provision if ART with prophylaxis on early-stage and adhrerence, implementation of the TB/HIV collaboration activity, and early initiation of ART to reduce opportunistic infections.


2019 ◽  
Author(s):  
Adey Girmay ◽  
Zelalem Tilahun ◽  
Muluemebet Zinabu Akele ◽  
solomon Assefa Huluka

Abstract Objective : Patients are essential sources of information to assess the accessibility and effectiveness of pharmaceutical care. Patients’ perception and satisfaction on the care they received has direct influence on treatment adherence. This study was thus aimed to assess HIV/AIDS patients’ level of satisfaction on the pharmaceutical services provided in Zewditu Memorial Hospital, Addis Ababa, Ethiopia. An institution based cross sectional study was conducted from April 16, 2018 to May 16, 2018 in Zewditu Memorial Hospital. Result: Among the total 285 participants enrolled in the study, 172(60.4%) of them were females and the mean age of the participants was 42.5±9.8. The participants of this study received ART service for a mean duration of 7.3±3.5 years. In this study, 26.7%, 13.7%, 38.6%, 13% and 8.1% of the study participants rated the overall satisfaction to the ART pharmaceutical service as excellent, very good, good, fair, and poor, respectively. Participants who were provided information about drug-drug and drug-food interaction were 2.72 times more likely to be satisfied than those who weren’t provided (AOR=2.72, 95%CI : 1.13-6.54).


2020 ◽  
Vol 35 (1) ◽  
pp. 59-66
Author(s):  
Arebu Issa Bilal ◽  
Bruck Messele ◽  
Dawit Teshome ◽  
Zelalem Tilahun ◽  
Teferi Gedif Fenta

In spite of an increase in the health service coverage of the country, studies reported that significant proportion of the Ethiopian population still relies on traditional medicine, particularly on the herbal aspect, for their healthcare. The aim of the present study was to determine the extent of the concomitant use of herbal medicines with modern antiretroviral medicines and identify the commonly used herbs among patients with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) in Ethiopia. A cross-sectional study was conducted from May to June, 2017 among HIV/AIDS patients in five hospitals selected from four regions and one city Administration (Addis Ababa). A total of 768 HIV/AIDS patients were successfully interviewed and included in the analysis. Most 480 (62.5%) of them were on tenofovir-disoproxil fumarate (TDF) plus lamivudine (3TC)and efavirenz (EFV) regimen. Two hundred nineteen (28.5%) patients reported that they had used herbal medicines to treat their illness; of these 145 (66.2%) used herbal products along with modern medicine. Of those who reported to have used herbal medicine with modern medicine, 53 (40.8%) claimed that they took the herbal medicines for the treatment of HIV/AIDS, while 51(39.2%) used for treating co-morbid diseases. Only 33 (15.0%) of those who used herbal medicines along with modern drugs discussed the issue either with their physicians or pharmacists. A total of 31 plant species were reported to be used for the treatment as well as alleviation of symptoms associated with the disease. The most commonly cited herbal medicines that  have been used by HIV/AIDS patients to treat their comorbid diseases were Moringa stenopetala (Baker f.) Cufod. (Moringaceae) (35.6%) followed by Ocimum lamiifolium Hochst. (Lamiaceae) (18.0%), Zheneria scabra Sond. (Cucurbitaceae) (7.2%), Allium sativum L. (Alliaceae) (5.7%), and Ruta chalapensis L. (Rutaceae) (5.7%). The study revealed that close to one-third of HIV/AIDS patients interviewed reported use of herbal medicine and almost two-thirds of them did so concomitantly with modern medicine. Only small percentage of the patients who used herbal medicines along with modern drugs disclose the use either to their treating physicians or to counselling pharmacists. Practitioners involved in antiretroviral therapy (ART) clinics, therefore, need to inquire information related to the use of herbal medicines and accordingly advise the patients. Keywords: HIV/AIDS, medicinal plant, cross-sectional study, concomitant use, Ethiopia  


2013 ◽  
Vol 7 (11) ◽  
pp. 868-872 ◽  
Author(s):  
Sintayehu Fekadu ◽  
Kefyalew Taye ◽  
Wondu Teshome ◽  
Solomon Asnake

Introduction: Intestinal parasitic infectionsare a major public health burden in tropical countries. Although all HIV/AIDS patients are susceptible to parasitic infections, those having lower immune status are at greater risk. The aim of this study was to determine the prevalence of intestinal parasitic infections in patients living with HIV/AIDS. Methodology: This was a facility-based cross-sectional study. A total of 343 consecutively sampled HIV/AIDS patients from the HIV care clinic of Hawassa University Referral Hospital were included. Subjects were interviewed for demographic variables and diarrheal symptoms using structured questionnaires. Stool examinations and CD4 cells counts were also performed. Results: The prevalence of intestinal parasitic infection was 47.8% among HIV/AIDS patients;  single helminthic infection prevalence (22.7%) was higher than that the prevalence of protozoal infections (14.6%). About 54% of study participants had chronic diarrhea while 3.4% had acute diarrhea. The prevalence of intestinal parasites in patients with chronic diarrhea was significantly higher than in acute diarrhea (p <0.05). Non-opportunistic intestinal parasite infections such as Ascaris lumbricoides, Taenia spp., and hookworm were commonlyfound, regardless of immunestatus or diarrheal symptoms. Opportunistic and non-opportunistic intestinal parasitic infection were more frequent in patients with a CD4 count of <200/mm3 (OR=9.5; 95% CI: 4.64-19.47) when compared with patients with CD4 counts of >=500 cells/mm3. Conclusions: Intestinal parasitic infections should be suspected in HIV/AIDS-infected patients with advanced disease presenting with chronic diarrhea. Patients with low CD4 counts should be examined critically for intestinal parasites, regardless of diarrheal status.


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