scholarly journals Opportunistic Infections and Associated Factors among HIV/AIDS Patients taking Ante-Retroviral Therapy at Selected Hospitals in Sidama Zone, Southern Ethiopia: A facility-based cross-sectional study

2019 ◽  
Author(s):  
Demelash Wachamo ◽  
Fisseha Bonja

Abstract Background Opportunistic infections are late complications of HIV infection is the depletion of the immune system. It is a major public health problem and high morbidity AIDS patients die of AIDS-related infections in developing countries like Ethiopia. Identification of opportunistic infections (OIs) is important to develop a specific intervention. Therefore, this study aimed to assess the burden and associated factors of opportunistic infections.Method A facility-based cross-sectional study was conducted on 420 randomly selected HIV/AIDS patients taking anti-retroviral therapy. Data was collected from selected hospitals in Sidama Zone based on population proportion to size. Data was collected by a pre-tested questionnaire and a pre-tested checklist from the medical records of patients. Data entry and analyzed for descriptive and logistic regression models by SPSS v.23. The result declared as statistically significant at p < 0.05.Result The magnitude of opportunistic infections was 39.6%. Major identified OIs was oral candidacies 23.2%, recurrent bacterial pneumonia 21.5%, Herpes zoster 6.3%, and Pulmonary Tuberculosis 6.0%.The magnitude of opportunistic associated with; older age [AOR=2.69, 95% CI: 1.33-5.43], No formal education [AOR=3.12, 95% CI: 1.06-9.25], Low monthly income [AOR=2.27, 95%CI:1.35-3.83], initial CD4 count less than 200 cells/mm3 [AOR=1.91, 95% CI:1.05-3.46), WHO clinical stage II [AOR=2.43, 95% CI:1.34-4.42] and stage III and IV [AOR=4.27, 95% CI: 2.12-8.59], had no extra medicine additional to ART (prophylaxis) had [AOR= 5.91, 95% CI: 3.31-10.56], who interrupt ART medicines [AOR=2.03, 95% CI: 1.09- 3.80] and Khat chewing [AOR=5.48, 95% CI: 2.32-12.96] when compared to their counterparts.Conclusions The overall magnitude of opportunistic infections was high when compared with other studies. Health officials and clinicians need to give attention on the strengthening of the provision if ART with prophylaxis on early-stage and adhrerence, implementation of the TB/HIV collaboration activity, and early initiation of ART to reduce opportunistic infections.

2019 ◽  
Author(s):  
Demelash Wachamo ◽  
Fisseha Bonja

Abstract Background Opportunistic infections are late complications of HIV infection is the depletion of the immune system. It is a major public health problem and high morbidity AIDS patients die of AIDS-related infections in developing countries like Ethiopia. Identification of opportunistic infections (OIs) is important to develop a specific intervention. Therefore, this study aimed to assess the burden and associated factors of opportunistic infections.Method A facility-based cross-sectional study was conducted on 420 randomly selected HIV/AIDS patients taking anti-retroviral therapy. Data was collected from selected hospitals in Sidama Zone based on population proportion to size. Data was collected by a pre-tested questionnaire and a pre-tested checklist from the medical records of patients. Data entry and analyzed for descriptive and logistic regression models by SPSS v.23. The result declared as statistically significant at p < 0.05.Result The magnitude of opportunistic infections was 39.6%. Major identified OIs was oral candidacies 23.2%, recurrent bacterial pneumonia 21.5%, Herpes zoster 6.3%, and Pulmonary Tuberculosis 6.0%.The magnitude of opportunistic associated with; older age [AOR=2.61, 95% CI: 1.30-5.23], No formal education [AOR=3.09, 95% CI: 1.11-8.60], monthly income below 1920 ETB [AOR=2.37, 95% CI: 1.43-3.94], initial CD4 count less than 200 cells/mm3 [AOR=2.30, 95% CI:1.06-4.98), had no extra medicine additional to ART (prophylaxis) had [AOR= 8.79, 95% CI: 5.05-15.30], who interrupt ART medicines [AOR=2.16, 95% CI: 1.19- 3.91] and Khat chewing [AOR=5.52, 95% CI: 2.42-12.56] when compared to their counterparts.Conclusions The overall magnitude of opportunistic infections was high when compared with other studies. Health officials and clinicians need to give attention to the strengthening of the provision if ART with prophylaxis on early-stage and adherence, implementation of the TB/HIV collaboration activity, and early initiation of ART to reduce opportunistic infections.


2019 ◽  
Author(s):  
Sisay Shine ◽  
Sindew Muhamud ◽  
Solomon Adnew ◽  
Alebachew Demelash

Abstract Introduction Diarrhea is responsible for 525,000 under five children deaths and 1.7 billion cases in the world and the second leading cause of death among under-five children. It is the major public health problem in developing countries like Ethiopia. The main aim of this study was to assess the prevalence and associated factors of diarrhea among under-five children in Debre Berhan Town, Ethiopia.Methods Community based cross-sectional study design was done among 420 children in Debre Behan Town. Multi-stage sampling technique was used to select the study participants. Data were collected by using pre-tested and structured questionnaire. Odds ratios with 95% confidence intervals were used to assess level of significance.Results The two week prevalence of diarrhea among under-five children was 16.4%. Age of children with 7-11 month years old (AOR: 4.2, 95%CI: 1.2 – 15.3), being the second children (AOR: 3.9, 95%CI: 1.8 – 8.5), not vaccinated against Rota virus (AOR: 10.3, 95%CI: 3.2 – 91.3) and feeding children by using hand (AOR: 2.5, 95%CI: 1.1 - 6.1) were significant predictors of under five children diarrhea.Conclusions This study revealed that the two weeks’ period prevalence of under-five diarrhea was relatively high. Age of children, vaccination against Rota virus and feeding children by using hand were associated with under-five children diarrhea. Education program on the important of vaccination against Rota virus and critical point of hand washing is recommended.


Author(s):  
Mariavinifa X. ◽  
Govindarajan P. K. ◽  
John William A. Felix

Background: There has been rapid growth on the internet not only in India, but also in worldwide. It is a major public health problem affecting an enormous number of individuals. The objective of the present study was to determine the prevalence of Internet addiction and its associated factors among college students using smartphone in Tamil Nadu.Methods: A cross sectional study was conducted in Annamalai University from October 2019 to October 2020.A total of five hundred students from various streams (medicine, dental, bachelor of physiotherapy, engineering, arts and science) were selected conveniently and a self-administered questionnaire was used to collect data. A questionnaire consisting of socio-demographic data, questions on internet usage and Young's internet addiction test were used to gather data. Descriptive Statistics was defined in terms of percentage and frequency. Inferential statistics was analysed with Chi-Square test.Results: Out of the five hundred students, 45.4% were males, 54.6 % were females .The users were divided into groups, 38.8 % as normal users, 37% as mild addicts, 21% as moderate addicts, 3.2% as severe addicts. Thus overall prevalence of internet addiction was 61.2%. Degree of internet addiction was significantly associated with age, time spent daily on the internet and using internet for social media, online communications and playing online games.Conclusions: The present study showed a prevalence of internet addiction is high among college students. Therefore, it’s essential to make awareness among the students to enhance their quality of life through the prevention of addictive usage of the internet.  


2021 ◽  
Vol 9 (4) ◽  
pp. 119-129
Author(s):  
James Ssekitooleko

Anemia during pregnancy is a major public health problem, with a global prevalence of 41.8%. It is associated with high morbidity and mortality. Information on the prevalence of anemia and associated factors among pregnant women in the study area is limited. This study aimed at determining the prevalence and predictors of anemia among pregnant women attending antenatal clinics (ANC) in Kyenjojo and Kole Districts, Uganda. Cross-sectional study was conducted among randomly selected pregnant women. Quantitative data was collected using a structured questionnaire that captured demographic and obstetric characteristics. Haemoglobin concentration (Hb) was determined using HemoCue 201+. The study outcome was the prevalence of anaemia (Hb <11 g/dl). Chi-square, odds ratio, and logistic regression were used to test for associations. Of the total 760 pregnant women who participated in this study, 20.1% were anaemic. The prevalence varied from 13.4% in Kyenjojo to 26.9% in Kole District. Of 153 anaemic women, 121 (97%) were mildly anaemic, 27 (18%) moderately anemic, and 5(3%) severely anemic. Malaria infection [AOR: 0.46, 95% CI (0.26 – 0.83)], primigravida [AOR: 0.52, 95% CI: 0.29-0.93], and residing in Kole [AOR: 0.50, 95% CI: 0.32-0.76] were significant predictors of low haemoglobin concentration. This study highlighted the high prevalence of anaemia in our settings and the significant association between anaemia and malaria among pregnant women. Therefore, routine screening of pregnant women for anemia, malaria, and other risk factors during their first ANC visit is recommended to identify those at risk and prompt management provided to curb their negative consequences.


2021 ◽  
Author(s):  
Getu Abeje Negatu ◽  
Getaneh Alemu Abebe ◽  
Woyneshet Gelaye Yalew

Abstract BackgroundMalaria is a major public health problem which still results in illness and death. Despite efforts to reduce the mortality and morbidity of malaria, the disease is still a prominent health problem in Ethiopia. This study, therefore, was undertaken to assess the prevalence of malaria and associated factors among symptomatic patients in northwest Ethiopia.MethodA facility based cross-sectional study was conducted from February to March 2020 among 210 febrile patients attending at Hamusite health center, northwest Ethiopia. Thin and thick blood films were prepared from blood collected by finger puncture and from capillary blood buffy coat. Data were analyzed using SPSS version 20.ResultsOut of 210 malaria suspected participants, 61 (29.0%) were confirmed to be infected by Plasmodium species. Plasmodium falciparum mono-infection was detected in 41 (19.5%) participants while P.vivax mono-infection and mixed infections were detected in 10 (4.3%) participants each. Female participant and those having family members with history of malaria were at higher risk of acquiring Plasmodium infectionConclusionThe present study revealed that malaria continued to be the major public health problem in the study area. Therefore, community mobilization should be strengthening in order to improve implementation of malaria control activities.


2020 ◽  
pp. 1-3
Author(s):  
Anup Latne ◽  
Prabhakar Jirvankar

Hypertension is a major public health problem all over the world. The incidence of hypertension is increasing year after year and the prevalence of hypertension is increasing day by day due to increased life expectancy and aging population and their sedentary lifestyle. Hypertension is known to cause microvascular changes and increased cardiovascular risk from it. Microalbuminuria possibly reflects a state of increased renal endothelial permeability and is an easily measured marker of rather diffuse endothelial dysfunction, low grade inflammation and vascular disease burden2. Microalbuminuria has been determined as an important prognostic indicator and has been reported to be associated with increased cardiovascular risk and progressive renal damage. Reliable data on the prevalence of microalbuminuria in the general population and its association with cardiovascular risk factors is limited. Till now, there is little data available regarding screening and early treatment of hypertensive patients with microalbuminuria, as in the case of microalbuminuric non diabetic subjects. With these perspective this cross sectional study of microalbuminuria in non-diabetic hypertensive patients was undertaken to study prevalence of microalbuminuria in Non Diabetic hypertensive patients. Objectives: To determine the prevalence of microalbuminuria in non-diabetic hypertensive patients and to correlate the presence of microalbuminuria with the patients of different clinical profiles. Materials and Methods: This was observational, cross sectional study of Patients diagnosed with hypertension either admitted in ward or attending OPD of Medical College and Tertiary Care Centre. Urine microalbumin creatinine ratio was used for estimation of microalbuminuria. Conclusion: It was proved that microalbuminuria prevalence was directly proportional to the duration of hypertension, the stage of hypertension. Prevalence of microalbuminria was low in ACE inhibitor and ARB treated hypertensive patients.


2019 ◽  
Vol 7 (1) ◽  
pp. 30
Author(s):  
Bharatkumar Balkrishna Pandya ◽  
Upendrakumar Rameshbhai Chaudhari ◽  
Avirat A. Bhatt ◽  
Nilesh Thakor

Background: Nutritional Anemia and visual impairment among school age children are recognized as major public health problem in India. Authors objective was to study prevalence of anemia and visual impairment among school going adolescents of Vadodara and Surat city of Gujarat, India.Methods: This cross sectional study was carried during period from April 2015 to March 2016. Total 8 schools were selected from Vadodara and Surat city by purposive sampling. After taking the permission of principals of schools and informed written consent of the parents of children, 859 children from these schools were examined for anaemia and visual impairment. The data was collected by predesign, pretested proforma and analysed using SPSS version 17 (Trial version).Results: Out of total 859 children 421(49.1%) were female. Mean age of the study children was 8.95±1.52 years. The prevalence of anemia in children in present study was 61.6 % (529 children). The prevalence of anemia in female (274, 65.1%) was higher than males (255, 58.2%). Moderate visual impairment and blindness was 5.9% in girls and 8.2% in boys respectively. Severe visual impairment and blindness was 2.1% in girls and 2.7% in boys respectively and the gender difference was not statistically significant. Though 61(7.1%) children had moderate to severe visual impairment to blindness only 21 (2.4%) children were wearing spectacles.Conclusions: High prevalence of anaemia and visual impairment among these children needs great attention and health education.


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