Evaluation of the prognostic role of centromere 17 gain and HER2/topoisomerase II alpha gene status and protein expression in patients with breast cancer treated with anthracycline-containing adjuvant chemotherapy: pooled analysis of two Hellenic Cooperative Oncology Group (HeCOG) phase III trials

George Fountzilas; Urania Dafni; Mattheos Bobos; Vassiliki Kotoula; Anna Batistatou; Ioannis Xanthakis; Christos Papadimitriou; Ioannis Kostopoulos; Triantafillia Koletsa; Eleftheria Tsolaki; Despina Televantou; Eleni Timotheadou; Angelos Koutras; George Klouvas; Epaminontas Samantas; Nikolaos Pisanidis; Charisios Karanikiotis; Ioanna Sfakianaki; Nicholas Pavlidis; Helen Gogas; Helena Linardou; Konstantine T Kalogeras; Dimitrios Pectasides; Meletios A Dimopoulos

doi:10.1186/1471-2407-13-163

Evaluation of the prognostic role of centromere 17 gain and HER2/topoisomerase II alpha gene status and protein expression in patients with breast cancer treated with anthracycline-containing adjuvant chemotherapy: pooled analysis of two Hellenic Cooperative Oncology Group (HeCOG) phase III trials

BMC Cancer ◽

10.1186/1471-2407-13-163 ◽

2013 ◽

Vol 13 (1) ◽

Cited By ~ 19

Author(s):

George Fountzilas ◽

Urania Dafni ◽

Mattheos Bobos ◽

Vassiliki Kotoula ◽

Anna Batistatou ◽

...

Keyword(s):

Topoisomerase Ii ◽

Pooled Analysis ◽

Phase Iii ◽

Oncology Group ◽

Prognostic Role ◽

Topoisomerase Ii Alpha ◽

Phase Iii Trials ◽

Alpha Gene ◽

Gene Status

Download Full-text

PD05-02: Effect of HER2/Topoisomerase II alpha (TOP2A) Gene Status or Protein Expression and Chromosome 17 (CEP17) Polysomy on the Outcome of Breast Cancer Patients Treated with Anthracycline-Containing Dose-Dense Sequential Adjuvant Chemotherapy with or without Paclitaxel – A Pooled Analysis of Two Hellenic Cooperative Oncology Group (HeCOG) Phase III Trials.

10.1158/0008-5472.sabcs11-pd05-02 ◽

2011 ◽

Cited By ~ 1

Author(s):

U Dafni ◽

M Bobos ◽

E Tsolaki ◽

A Batistatou ◽

F Koletsa ◽

...

Keyword(s):

Topoisomerase Ii ◽

Pooled Analysis ◽

Phase Iii ◽

Chromosome 17 ◽

Breast Cancer Patients ◽

Topoisomerase Ii Alpha ◽

Top2a Gene ◽

Phase Iii Trials ◽

Gene Status ◽

Dose Dense

Download Full-text

The topoisomerase II alpha gene status in primary breast cancer is a predictive marker of the response to anthracycline-based neoadjuvant chemotherapy

Pathology - Research and Practice ◽

10.1016/j.prp.2009.10.009 ◽

2010 ◽

Vol 206 (3) ◽

pp. 156-162 ◽

Cited By ~ 5

Author(s):

Kae Kawachi ◽

Takeshi Sasaki ◽

Ayumi Murakami ◽

Takashi Ishikawa ◽

Ayako Kito ◽

...

Keyword(s):

Breast Cancer ◽

Neoadjuvant Chemotherapy ◽

Primary Breast Cancer ◽

Topoisomerase Ii ◽

Predictive Marker ◽

Topoisomerase Ii Alpha ◽

Alpha Gene ◽

Gene Status

Download Full-text

A meta-analysis of phase III trials evaluating the predictive value of HER2 and topoisomerase II alpha in early breast cancer patients treated with CMF or anthracycline-based adjuvant therapy.

10.1158/0008-5472.sabcs-705 ◽

2009 ◽

Cited By ~ 14

Author(s):

A Di Leo ◽

J Isola ◽

F Piette ◽

B Ejlertsen ◽

KI Pritchard ◽

...

Keyword(s):

Breast Cancer ◽

Adjuvant Therapy ◽

Cancer Patients ◽

Predictive Value ◽

Topoisomerase Ii ◽

Meta Analysis ◽

Phase Iii ◽

Breast Cancer Patients ◽

Topoisomerase Ii Alpha ◽

Phase Iii Trials

Download Full-text

Impact of age on tolerance of chemoradiation and survival for patients with local regionally advanced cervical cancer: A pooled analysis of Gynecologic Oncology Group (GOG) phase III trials

Gynecologic Oncology ◽

10.1016/j.ygyno.2014.03.114 ◽

2014 ◽

Vol 133 ◽

pp. 38-39

Author(s):

K.N. Slaughter ◽

J. Java ◽

F.B. Stehman ◽

P.G. Rose ◽

K.N. Moore ◽

...

Keyword(s):

Cervical Cancer ◽

Gynecologic Oncology ◽

Pooled Analysis ◽

Phase Iii ◽

Gynecologic Oncology Group ◽

Advanced Cervical Cancer ◽

Oncology Group ◽

Phase Iii Trials

Download Full-text

5178 POSTER Response of Immunohistochemically (IHC) Defined Breast Cancer Sub-types to Dose-dense Sequential Adjuvant Chemotherapy. Pooled Analysis of Two Randomized Hellenic Cooperative Oncology Group (HeCOG) Phase III Trials

European Journal of Cancer ◽

10.1016/s0959-8049(11)71620-3 ◽

2011 ◽

Vol 47 ◽

pp. S383-S384

Author(s):

G. Fountzilas ◽

M. Bobos ◽

C. Papadimitriou ◽

H. Gogas ◽

H. Linardou ◽

...

Keyword(s):

Breast Cancer ◽

Adjuvant Chemotherapy ◽

Pooled Analysis ◽

Phase Iii ◽

Oncology Group ◽

Phase Iii Trials ◽

Dose Dense

Download Full-text

Assessment of topoisomerase II-alpha gene status by dual color chromogenic in situ hybridization in a set of Iraqi patients with invasive breast carcinoma

Indian Journal of Pathology and Microbiology ◽

10.4103/ijpm.ijpm_62_16 ◽

2017 ◽

Vol 60 (4) ◽

pp. 475

Author(s):

RashaAbd Alraouf Neama ◽

ManalA Habib ◽

SahiraA Ali ◽

AliH Al-Khafaji ◽

MohammedF Alqanbar

Keyword(s):

In Situ Hybridization ◽

Breast Carcinoma ◽

Topoisomerase Ii ◽

Invasive Breast Carcinoma ◽

Topoisomerase Ii Alpha ◽

Dual Color ◽

Alpha Gene ◽

Chromogenic In Situ Hybridization ◽

Gene Status

Download Full-text

Efficacy and Safety of Moxifloxacin in Hospitalized Patients with Secondary Peritonitis: Pooled Analysis of Four Randomized Phase III Trials

Surgical Infections ◽

10.1089/sur.2013.045 ◽

2014 ◽

Vol 15 (5) ◽

pp. 567-575 ◽

Cited By ~ 3

Author(s):

Jan J. De Waele ◽

Jose M. Tellado ◽

Günter Weiss ◽

Jeffrey Alder ◽

Frank Kruesmann ◽

...

Keyword(s):

Pooled Analysis ◽

Hospitalized Patients ◽

Secondary Peritonitis ◽

Phase Iii ◽

Efficacy And Safety ◽

Phase Iii Trials

Download Full-text

Long‐term evaluation of combined prolonged‐release oxycodone and naloxone in patients with moderate‐to‐severe chronic pain: pooled analysis of extension phases of two Phase III trials

Neurogastroenterology & Motility ◽

10.1111/nmo.12463 ◽

2014 ◽

Vol 26 (12) ◽

pp. 1792-1801 ◽

Cited By ~ 17

Author(s):

M. Blagden ◽

J. Hafer ◽

H. Duerr ◽

M. Hopp ◽

B. Bosse

Keyword(s):

Chronic Pain ◽

Pooled Analysis ◽

Phase Iii ◽

Prolonged Release ◽

Two Phase ◽

Phase Iii Trials ◽

Severe Chronic Pain ◽

Term Evaluation

Download Full-text

Topoisomerase II alpha gene amplification is a favorable prognostic factor in patients with HER2-positive metastatic breast cancer treated with trastuzumab

Journal of Translational Medicine ◽

10.1186/1479-5876-10-212 ◽

2012 ◽

Vol 10 (1) ◽

Cited By ~ 18

Author(s):

George Fountzilas ◽

Christos Christodoulou ◽

Mattheos Bobos ◽

Vassiliki Kotoula ◽

Anastasia G Eleftheraki ◽

...

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Prognostic Factor ◽

Gene Amplification ◽

Topoisomerase Ii ◽

Metastatic Breast ◽

Her2 Positive ◽

Topoisomerase Ii Alpha ◽

Favorable Prognostic Factor ◽

Alpha Gene

Download Full-text

Safety of Injectable HPβCD-Diclofenac in Older Patients with Acute Moderate-to-Severe Postoperative Pain: A Pooled Analysis of Three Phase III Trials

Drugs & Aging ◽

10.1007/s40266-018-0529-3 ◽

2018 ◽

Vol 35 (3) ◽

pp. 249-259 ◽

Cited By ~ 1

Author(s):

Jacques E. Chelly ◽

Peter G. Lacouture ◽

Christian Russel D. Reyes

Keyword(s):

Postoperative Pain ◽

Older Patients ◽

Pooled Analysis ◽

Phase Iii ◽

Three Phase ◽

Severe Postoperative Pain ◽

Phase Iii Trials

Download Full-text