scholarly journals Long-term CPAP treatment partially improves the link between cardiac vagal influence and delta sleep

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Fabrice Jurysta ◽  
Chantal Kempenaers ◽  
Jean-Pol Lanquart ◽  
André Noseda ◽  
Philippe van de Borne ◽  
...  
2012 ◽  
Vol 27 ◽  
pp. 1
Author(s):  
F. Jurysta ◽  
C. Kempenaers ◽  
J.-P. Lanquart ◽  
P. Linkowski
Keyword(s):  

Author(s):  
Cristina Navarro-Soriano ◽  
Miguel-Angel Martínez-García ◽  
Gerard Torres ◽  
Ferrán Barbé ◽  
Manuel Sánchez-de-la-Torre ◽  
...  

1995 ◽  
Vol 73 (9) ◽  
pp. 1235-1245 ◽  
Author(s):  
Vladimir M. Pokrowsky ◽  
Oleg E. Osadchiy

When the right vagus nerve of anesthetized cats was stimulated with repetitive bursts of pulses, decelerated heart rate became synchronized to the rhythm of the vagal bursts. Each burst applied to the vagus was followed by a single heart contraction. Within defined limits an increase in the frequency of vagal bursts evoked a proportional acceleration of the heart, whereas a decreased frequency diminished the heart rate. Therefore, over the range of synchronization the heart rate was precisely controlled by changing the vagal stimulation rate. We concluded that the chronotropic effect evoked by vagal bursts was composed of two functionally different types of influence, namely, inhibitory tonic and synchronizing. The vagotropic influence of intravenously injected regulatory peptides was found to be selective for either the tonic or synchronizing component. For instance, dalargin (D-Ala2-Leu5-Arg6-enkephalin) and neokyotorphin selectively diminished the inhibitory tonic vagal influence, whereas delta sleep inducing peptide and neurotensin potentiated it. The magnitude of synchronizing vagal influence was not modified by these peptides. In contrast, secretin selectively inhibited the synchronizing vagal effect, but the tonic one was not affected. Somatostatin potentiated the synchronizing effect but diminished the tonic one. These data support the hypothesis that certain regulatory peptides can modulate the effects of repetitive vagal bursts on pacemaker activity.Key words: vagus nerve, burst stimulation, controlled bradycardia, regulatory peptides.


2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Anders Broström ◽  
Per Nilsen ◽  
Benjamin Gardner ◽  
Peter Johansson ◽  
Martin Ulander ◽  
...  

Long-term adherence to continuous positive airway pressure (CPAP) is low among patients with obstructive sleep apnea (OSA). The potential role of “habit” in sustaining adherence to CPAP use has not been studied. This study aimed to establish the relevance of habit to CPAP adherence, via validation of an adaptation of the Self-Report Habit Index (the CPAP Habit Index-5; CHI-5). Analyses focused on the homogeneity, reliability, and factor structure of the CHI-5 and, in line with theoretical predictions, its utility as a predictor of long-term CPAP adherence in middle-aged patients with OSA. A prospective longitudinal design was used. 117 patients with objectively verified OSA intended for CPAP treatment were recruited. Data was collected via clinical examinations, respiratory recordings, questionnaires, and CPAP devices at baseline, 2 weeks, 6 months, and 12 months. The CHI-5 showed satisfactory homogeneity interitem correlations (0.42–0.93), item-total correlations (0.58–0.91), and reliability (α= 0.92). CHI-5 data at 6 months showed a one-factor solution and predicted 63% of variance in total CPAP use hours after 12 months. Based on the satisfactory measurement properties and the high amount of CPAP use variance it explained, the CHI-5 can be seen as a useful tool in clinical practice.


Author(s):  
Ferran Barbé ◽  
Joquin Duran-Cantolla ◽  
Carmen Carmona ◽  
Mónica de la Peña ◽  
Eusebi Chiner ◽  
...  

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