scholarly journals An administrative data validation study of the accuracy of algorithms for identifying rheumatoid arthritis: the influence of the reference standard on algorithm performance

2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Jessica Widdifield ◽  
Claire Bombardier ◽  
Sasha Bernatsky ◽  
J Michael Paterson ◽  
Diane Green ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Administrative Data ◽  
Validation Study ◽  
Data Validation ◽  
Reference Standard ◽  
Algorithm Performance

Syncope and Presyncope as a Presenting Symptom or Discharge Diagnosis in the Emergency Department: An Administrative Data Validation Study

2017 ◽  
Vol 33 (12) ◽  
pp. 1729-1732
Author(s):  
John A. Staples ◽  
Cristian Vadeanu ◽  
Bobby Gu ◽  
Shannon Erdelyi ◽  
Herbert Chan ◽  
...  
Keyword(s):  
Emergency Department ◽  
Administrative Data ◽  
Validation Study ◽  
Discharge Diagnosis ◽  
Data Validation

scholarly journals Accuracy of Administrative Data for the Coding of Acute Stroke and TIAs

2016 ◽  
Vol 43 (6) ◽  
pp. 765-773 ◽  
Author(s):  
Ruth Hall ◽  
Luke Mondor ◽  
Joan Porter ◽  
Jiming Fang ◽  
Moira K. Kapral
Keyword(s):  
Ischemic Stroke ◽  
Acute Stroke ◽  
Administrative Data ◽  
Data Validation ◽  
Reference Standard ◽  
Stroke Registry ◽  
Diagnostic Codes ◽  
Icd 10 ◽  
Stroke Type ◽  
Ischemic Attack

AbstractObjective: Administrative data validation is essential for identifying biases and misclassification in research. The objective of this study was to determine the accuracy of diagnostic codes for acute stroke and transient ischemic attack (TIA) using the Ontario Stroke Registry (OSR) as the reference standard. Methods: We identified stroke and TIA events in inpatient and emergency department (ED) administrative data from eight regional stroke centres in Ontario, Canada, from April of 2006 through March of 2008 using ICD–10–CA codes for subarachnoid haemorrhage (I60, excluding I60.8), intracerebral haemorrhage (I61), ischemic (H34.1 and I63, excluding I63.6), unable to determine stroke (I64), and TIA (H34.0 and G45, excluding G45.4). We linked administrative data to the Ontario Stroke Registry and calculated sensitivity and positive predictive value (PPV). Results:: We identified 5,270 inpatient and 4,411 ED events from the administrative data. Inpatient administrative data had an overall sensitivity of 82.2% (95% confidence interval [CI95%]=81.0, 83.3) and a PPV of 68.8% (CI95%=67.5, 70.0) for the diagnosis of stroke, with notable differences observed by stroke type. Sensitivity for ischemic stroke increased from 66.5 to 79.6% with inclusion of I64. The sensitivity and PPV of ED administrative data for diagnosis of stroke were 56.8% (CI95%=54.8, 58.7) and 59.1% (CI95%=57.1, 61.1), respectively. For all stroke types, accuracy was greater in the inpatient data than in the ED data. Conclusion: The accuracy of stroke identification based on administrative data from stroke centres may be improved by including I64 in ischemic stroke type, and by considering only inpatient data.

scholarly journals Linkage of a De-Identified United States Rheumatoid Arthritis Registry With Administrative Data to Facilitate Comparative Effectiveness Research

2014 ◽  
Vol 66 (12) ◽  
pp. 1790-1798 ◽  
Author(s):  
Jeffrey R. Curtis ◽  
Lang Chen ◽  
Aseem Bharat ◽  
Elizabeth Delzell ◽  
Jeffrey D. Greenberg ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
United States ◽  
Administrative Data ◽  
Comparative Effectiveness Research ◽  
Comparative Effectiveness ◽  
Effectiveness Research

scholarly journals Development and psychometric validation of a patient-reported outcome measure to assess fears in rheumatoid arthritis and axial spondyloarthritis: the Fear Assessment in Inflammatory Rheumatic diseases (FAIR) questionnaire

2017 ◽  
Vol 77 (2) ◽  
pp. 258-263 ◽  
Author(s):  
Laure Gossec ◽  
Pierre Chauvin ◽  
Alain Saraux ◽  
Christophe Hudry ◽  
Gabrielle Cukierman ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Internal Consistency ◽  
Validation Study ◽  
Outcome Measure ◽  
Axial Spondyloarthritis ◽  
Psychometric Validation ◽  
Routine Practice ◽  
Inflammatory Rheumatic Diseases ◽  
Patient Reported

ObjectivesTo develop and validate an outcome measure for assessing fears in patients with rheumatoid arthritis (RA) and axial spondyloarthritis (axSpA).MethodsFears were identified in a qualitative study, and reformulated as assertions with which participants could rate their agreement (on a 0–10 numeric rating scale). A cross-sectional validation study was performed including patients diagnosed with RA or axSpA. Redundant items (correlation >0.65) were excluded. Internal consistency (Cronbach’s α) and factorial structure (principal component analysis) were assessed. Patients were classified into fear levels (cluster analysis). Associations between patient variables and fear levels were evaluated using multiple logistic regression.Results672 patients were included in the validation study (432 RA, 240 axSpA); most had moderate disease activity and were prescribed biologics. The final questionnaire included 10 questions with high internal consistency (α: 0.89) and a single dimension. Mean scores (±SD) were 51.2 (±25.4) in RA and 60.5 (±22.9) in axSpA. Groups of patients with high (17.2%), moderate (41.1%) and low (41.7%) fear scores were identified. High fear scores were associated with high Arthritis Helplessness Index scores (OR 6.85, 95% CI (3.95 to 11.87)); high Hospital Anxiety and Depression Scale anxiety (OR 5.80, 95% CI (1.19 to 4.22)) and depression (OR 2.37, 95% CI (1.29 to 4.37)) scores; low education level (OR 3.48, 95% CI (1.37 to 8.83)); and high perceived disease activity (OR 2.36, 95% CI (1.10 to 5.04)).ConclusionsOverall, 17.2% of patients had high fear scores, although disease was often well controlled. High fear scores were associated with psychological distress. This questionnaire could be useful both in routine practice and clinical trials.

Reproducibility of Joint Swelling Assessment by Sonography in Patients with Long-lasting Rheumatoid Arthritis (SEA-Repro Study Part II)

2010 ◽  
Vol 37 (5) ◽  
pp. 938-945 ◽  
Author(s):  
SANDRINE JOUSSE-JOULIN ◽  
MARIA ANTONIETTA d’AGOSTINO ◽  
THIERRY MARHADOUR ◽  
JEAN DAVID ALBERT ◽  
JACQUES BENTIN ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Physical Examination ◽  
Disease Activity Score ◽  
Power Doppler ◽  
Kappa Statistic ◽  
Reference Standard ◽  
Interobserver Reproducibility ◽  
Grading Systems ◽  
The Difference ◽  
Good Agreement

Objective.To evaluate the intraobserver and interobserver reproducibility of B-mode and power Doppler (PD) sonography in patients with active long-standing rheumatoid arthritis (RA) comparatively with clinical data.Methods.In each of 7 patients being considered for a change in their RA treatment regimen, 7 healthcare professionals examined the 28 joints used in the Disease Activity Score 28-joint count (DAS28). Then 7 sonographers examined each of the 7 patients twice, using previously published B-mode and PD grading systems. The clinical reference standard was presence of synovitis according to at least 4/7 examiners. The sonographic reference standard was at least grade 1 (ALG1) or 2 (ALG2) synovitis according to at least 4/7 sonographers. Interobserver reproducibility of sonography was assessed versus the sonographer having the best intraobserver reproducibility. Agreement was measured by Cohen’s kappa statistic.Results.Intraobserver and interobserver reproducibility of B-mode and PD used separately was fair to good. Agreement between clinicians and sonographers at all sites using B-mode, PD, and both was 0.46, 0.37, and 0.36, respectively, for grade 1 synovitis; and 0.58, 0.19, and 0.19 for grade 2 synovitis. The number of joints with synovitis was smaller by physical examination (36.7%) than by B-mode with ALG1 (58.6%; p < 0.001). The number of joints with synovitis was higher by physical examination than by PD with both ALG1 (17.8%; p < 0.0001) and ALG2 (6.6%; p < 0.0001).Conclusion.PD findings explain most of the difference between clinical and sonographic joint assessments for synovitis in patients with long-standing RA.

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