scholarly journals Cytologic features of nipple aspirate fluid using an automated non-invasive collection device: a prospective observational study

2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Kerry AS Proctor ◽  
Leslie R Rowe ◽  
Joel S Bentz
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
G. Simpson ◽  
R. N. Rodseth

Abstracts Background Patient outcomes are influenced by intraoperative temperature management. Oesophageal/pharyngeal temperature monitoring is the standard of care at our institute but is not well tolerated in awake patients. Many non-invasive temperature monitors have been studied. Only the TraxIt® Wearable Children’s Underarm Thermometer which contains liquid crystals that undergo phase changes according to temperature is available at our institution. We tested these non-invasive monitors against our standard of care which is the oesophageal/pharyngeal temperature monitor. Methods We conducted a prospective observational study of 100 patients receiving general anaesthesia for elective surgery. Patients were eligible for inclusion if they were ≥ 18 years old, were planned to have a general anaesthetic > 60 min during which no body cavity (chest or abdomen) would be opened. Patient temperature was measured with an oesophageal/pharyngeal thermistor probe and skin surface temperature monitors placed over the forehead, in the axilla, over the sternum, and behind the ear (over major vessels to the brain). Temperatures were recorded and then analysed using Altman-Bland plots. Pre-determined clinically relevant limits of agreement were set at −/+ 0.5 °C. Results From the 100 patients we collected 500 data points for each monitor with an average monitoring time of 102 min (30–300 min) across a range of surgical procedures. None of the skin surface temperature monitors achieved the pre-determined limits of agreement and results were impacted by the use of a forced air warmer. Conclusion The TraxIt® Wearable Children’s Underarm Thermometers are not suitable for temperature monitoring during general anaesthesia.


2021 ◽  
Vol 9 ◽  
Author(s):  
Luca Bedetti ◽  
Licia Lugli ◽  
Lucia Marrozzini ◽  
Alessandro Baraldi ◽  
Federica Leone ◽  
...  

Objective: This study aims to evaluate safety and success rates of lumbar puncture (LP) and to identify factors associated with adverse events or failure of LP in infants.Methods: This two-center prospective observational study investigated infants younger than 90 days of age who underwent LP. Need for resuscitation oxygen desaturation (SpO2 < 90%), bradycardia and intraventricular hemorrhage were considered adverse events. LP failed if cerebrospinal spinal fluid was not collected or had traces of blood. Logistic regression analysis was used to evaluate whether corrected gestational age (GA), body weight at LP, position, and any respiratory support during LP affected SpO2 desaturation or failure of LP.Results: Among 204 LPs, 134 were performed in full-term and 70 in pre-term born infants. SpO2 desaturations occurred during 45 (22.4%) LPs. At multivariate analysis, lower GA at LP (p < 0.001), non-invasive respiratory support (p 0.007) and mechanical ventilation (p 0.004) were associated with SpO2 desaturations. Transient, self-resolving bradycardia occurred in 7 (3.4%) infants. Two infants had intraventricular hemorrhage detected within 72 h of LP. No further adverse events were registered. Failure of LP occurred in 38.2% of cases and was not associated with any of the factors evaluated.Conclusions: LP was safe in most infants. Body weight or GA at LP did not affect LP failure. These data are useful to clinicians, providing information on the safety of the procedure.


2021 ◽  
pp. respcare.09162
Author(s):  
Nicolas Colaianni-Alfonso ◽  
Guillermo Montiel ◽  
Mauro Castro-Sayat ◽  
Catalina Siroti ◽  
Maria Laura Vega ◽  
...  

PLoS Medicine ◽  
2017 ◽  
Vol 14 (7) ◽  
pp. e1002356 ◽  
Author(s):  
Chiara Robba ◽  
Danilo Cardim ◽  
Tamara Tajsic ◽  
Justine Pietersen ◽  
Michael Bulman ◽  
...  

2021 ◽  
Vol 68 (5) ◽  
pp. 729-731
Author(s):  
Reinhard Hahn ◽  
Aylin Bilir ◽  
Ulrike Weber ◽  
Oliver Kimberger ◽  
Stephan Kettner

2010 ◽  
Vol 68 ◽  
pp. 261-261
Author(s):  
J Mayordomo-Colunga ◽  
A Medina ◽  
C Rey ◽  
S Menéndez ◽  
A Concha ◽  
...  

Author(s):  
Carolina Solé-Delgado ◽  
Alberto García-Salido ◽  
Ainhoa Gochi-Valdovinos ◽  
Anthony González-Brabin ◽  
Maria García ◽  
...  

Background: in recent years, High Flow Nasal Cannula (HFNC) has been considered an alternative to non-invasive mechanical ventilation (NIMV) in severe asthma respiratory management in children. Objective: to describe the use of HFNC in children with severe asthma admitted to pediatric critical care unit (PICU). To compare its clinical characteristic and evolution with those receiving NIMV or other respiratory support. Methods: prospective observational study done in children admitted to PICU with severe asthma (October 2017 to October 2019). Data collected: epidemiological, clinical, respiratory support, thorax x-ray, pharmacological treatments and days of admission. Patients were divided into groups: 1) Only HFNC 2) HFNC and NIMV, and 3) Only NIMV. Results: Seventy-six patients included, 39 girls. The median age was two years and one month (range 160). The median pulmonary score was 5 (range 7). PICU admission lengths a median of 3 days (range 9), hospital 6 days (range 23). There were no epidemiological or clinical differences between groups. Children with only HNFC showed a shorter time of PICU days (p 0,025) and none of them required NIMV. In the group receiving both modalities, NIMV was used first and then HFNC in all cases. Children with HFNC showed higher SaO2/FiO2 ratio (p=0,025) and lower PCO2 level (p=0,032). There were no deaths. Conclusions: in our study the HFNC did not require escalation to NIMV and did not increase the length of PICU or hospital days. Normal initial blood gases and absence of high oxygen requirements were useful to select responders to HNFC.


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