scholarly journals Nutritional related cardiovascular risk factors in patients with coronary artery disease in IRAN: A case-control study

2010 ◽  
Vol 9 (1) ◽  
Author(s):  
Reza Amani ◽  
Mohammad Noorizadeh ◽  
Samira Rahmanian ◽  
Naser Afzali ◽  
Mohammad H Haghighizadeh
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Cardiovascular Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Artery Disease ◽  
Control Study

scholarly journals Association of traditional cardiovascular risk factors in adults younger than 55 years with coronary heart disease. Case-control study

2020 ◽  
Vol 8 ◽  
pp. 205031212093270
Author(s):  
Fernando Guerrero-Pinedo ◽  
Laura Ochoa-Zárate ◽  
Camilo J Salazar ◽  
Diana Cristina Carrillo-Gómez ◽  
Manuel Paulo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Arterial Hypertension ◽  
Cardiovascular Risk Factors ◽  
Odds Ratio ◽  
Case Control Study ◽  
Artery Disease ◽  
Control Study

Objectives: The traditional cardiovascular risk factors associated with coronary artery disease in individuals younger than 55 years old was determined in this study. Methods: A retrospective, paired case–control study comprised of patients younger than 55 years old who were admitted to the hospital due to acute coronary syndrome with coronary artery disease from 2011 to 2016. There were two controls per case, paired by age, gender, admission date, and health insurance. Data from patients were collected, such as sociodemographic information, cardiovascular risk factors, and drug therapy information. A conditional logistic regression model was created to evaluate the association between traditional cardiovascular risk factors and coronary artery disease. Results: There were 171 cases and 342 controls included in the study. The median age was 49 years, with a predominance of male gender (80.12%). Nearly 66% of cases had at least one traditional cardiovascular risk factor. The most common risk factors were obesity (57.31%), arterial hypertension (45.62%), and smoking (28.97%). Independent risk factors of coronary artery disease in patients younger than 55 years were arterial hypertension (odds ratio, 2.52; 95% confidence interval, 1.48–4.20; p = 0.001) and smoking (odds ratio, 7.15; 95% confidence interval, 3.19–15.99; p = 0.00). No significant association between diabetes mellitus and coronary heart disease in the global group (odds ratio, 2.04; 95% confidence innterval, 0.91–4.58; p = 0.083) was found. Conclusion: For patients younger than 55 years, with a theoretically lower risk of coronary artery disease due to their age, having one or several traditional risk factors (smoking, arterial hypertension, dyslipidemia, or diabetes mellitus) confers an increased risk of coronary artery disease regardless of age.

scholarly journals Association of smoking with coronary artery disease in Nepalese populations: a case control study

2019 ◽  
Vol 8 (5) ◽  
pp. 677-685
Author(s):  
Til Bahadur Basnet ◽  
Cheng Xu ◽  
Manthar Ali Mallah ◽  
Wiwik Indayati ◽  
Cheng Shi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Case Control Study ◽  
Case Control ◽  
Psychosocial Risk ◽  
Psychosocial Risk Factor ◽  
Artery Disease ◽  
Control Study

Abstract There are well-known traditional risk factors for coronary artery disease (CAD). Among them, smoking is one of the most prominent and modifiable risk factors. This study aims to determine the magnitude of smoking as a risk factor for CAD in the Nepalese population. A hospital-based age- and sex-matched case–control study was carried out with a total of 612 respondents. Bivariate analysis showed that the risk of developing CAD in ex-smokers and current smokers was higher (odds ratio (OR): 1.81 (confidence interval (CI): 1.21–2.7) and OR: 5.2 (CI: 3.4–7.97)), with p-values less than 0.004 and <0.00001, respectively, compared to the risk in never smokers. From stratified socio-demographic, cardio-metabolic, behavioural and psychosocial risk factor analysis, smoking was found to be associated with CAD in almost all subgroups. In the subsequent multivariate analysis, adjustment for socio-demographic, cardio-metabolic and psychosocial risk factors showed a steady increase in risk. However, further adjustment for behavioural risk factors (alcohol use and physical activity) showed that the risk was attenuated by 59% in current smokers. After adjusting for the covariates, current smokers and ex-smokers had an increased risk of CAD (OR: 6.64, 95% CI: 3.64–12.12, p < 0.00001; OR: 1.89, 95% CI: 1.08–3.31, p < 0.012, respectively) compared with non-smokers. In conclusion, smoking was found to increase the risk of CAD in the Nepalese population.

A Case-Control Study on the Risk Factors for Coronary Artery Disease among Korean

1998 ◽  
Vol 28 (6) ◽  
pp. 849 ◽  
Author(s):  
Hye Soon Park ◽  
Young Sik Kim ◽  
Won-Ki Min ◽  
Chul Whan Lee ◽  
Seong-Wook Park ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Case Control Study ◽  
Case Control ◽  
Artery Disease ◽  
Control Study

scholarly journals Association of LpPLA2 with coronary artery disease a hospital-based case control study

2022 ◽  
Vol 8 (4) ◽  
pp. 297-303
Author(s):  
Jaideep C Menon ◽  
Rajesh Thachathodiyil ◽  
Anugrah Nair ◽  
Rajiv Chandrasekhar ◽  
Natarajan Kumaraswamy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Case Control Study ◽  
Case Control ◽  
Apo B ◽  
Hs Crp ◽  
Artery Disease ◽  
Control Study ◽  
Conventional Risk Factors

Coronary artery disease (CAD) in Asian-Indians is characterised by an earlier onset and more severe disease when compared to Western populations. It is estimated that about 20% of patients presenting with an acute coronary syndrome do not have any of the conventional risk factors for CAD. To assess the risk posed by each of the newer risk factors; alongside conventional risk factors namely diabetes, hypertension, dyslipidaemia for coronary artery disease and to compare the relative risk in a case-control design. Department of Cardiology, XXX Institute of Medical sciences (XXX). Case control study design. Cases are as any individual with coronary artery disease and controls included patients with non-coronary conditions. Dependant variable: coronary artery disease (CAD); Independent variables: Lp PLA2, Lp(a), Apo(a), Apo(b), Ratio (Apo B/Apo A); Other predictors- diabetes mellitus, hypertension, dyslipidaemia, tobacco use Categorical variables were presented as frequencies and percentages. Chi-square test and binary logistic regression analysis was used to study the comparison and association of the categorical risk factors with the disease status, respectively. Software used was SPSS version 20.0. A total of 253 participants aged between 19 and 90 years; 140 cases and 113 controls were enrolled in this study. Except for the hs-CRP level, alcohol consumption and LDL, all the other risk factors were seen significantly associated with the coronary artery disease; dyslipidaemia (10.8, 95% CI 3.29-35.37), gender- male (4.68, 95% CI 2.12-10.30), diabetes mellitus (3.3, 95% CI 1.6 -6.77), lipoprotein(a) more than 30mg% (2.34, 95% CI 1.06-5.15) and hypertension (2.48, 95% CI 1.14-5.39). Conventional risk factors namely diabetes, hypertension and dyslipdaemia showed a statistically significant association with CAD while from among the biochemical markers the association was statistically significant only for Lp(a) when compared both between cases and controls and also in cases < age 50 years. The other biochemical risk factors namely Lp-PLA2, Apo(A1) and Apo(b) showed a weak degree of association with CAD. In the present study we analyse the role of inflammatory mediators of CAD (hs-CRP, Lp-PLA2), pro-thrombotic markers [Lp(a)] alongside the lipid fractions apoB, apo A and their ratio to assess which of these biochemical markers predisposed one to CAD through assessment of the relative risk.

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