scholarly journals Coronary MR Angiography in patients with coronary artery disease using image-based respiratory motion compensation

2015 ◽  
Vol 17 (S1) ◽  
Author(s):  
Markus Henningsson ◽  
Konstantinos Bratis ◽  
Eike Nagel ◽  
Rene Botnar
Radiology ◽  
2005 ◽  
Vol 234 (3) ◽  
pp. 718-725 ◽  
Author(s):  
Torsten Sommer ◽  
Matthias Hackenbroch ◽  
Ulrich Hofer ◽  
Alexandra Schmiedel ◽  
Winfried A. Willinek ◽  
...  

Author(s):  
Stephanie Lehrke ◽  
Benjamin Egenlauf ◽  
Henning Steen ◽  
Dirk Lossnitzer ◽  
Grigorius Korosoglou ◽  
...  

2019 ◽  
Vol 144 (05) ◽  
pp. 308-314
Author(s):  
Christoph Thalhammer ◽  
Iris Baumgartner

AbstractArteriosclerosis is a generalized disease and manifests in different vascular regions: the most important manifestations are the coronary artery disease, the peripheral artery disease and the cerebrovascular arteriosclerosis. The challenges of modern ultrasound systems to detect early vascular damage are reviewed in this article. Colour coded duplex ultrasound is the first line method for screening and diagnostic imaging in vascular disease. Indications for further imaging as CT-angiography, MR-angiography and digital subtraction angiography will be discussed in the different sections.


2019 ◽  
Vol 133 (22) ◽  
pp. 2283-2299
Author(s):  
Apabrita Ayan Das ◽  
Devasmita Chakravarty ◽  
Debmalya Bhunia ◽  
Surajit Ghosh ◽  
Prakash C. Mandal ◽  
...  

Abstract The role of inflammation in all phases of atherosclerotic process is well established and soluble TREM-like transcript 1 (sTLT1) is reported to be associated with chronic inflammation. Yet, no information is available about the involvement of sTLT1 in atherosclerotic cardiovascular disease. Present study was undertaken to determine the pathophysiological significance of sTLT1 in atherosclerosis by employing an observational study on human subjects (n=117) followed by experiments in human macrophages and atherosclerotic apolipoprotein E (apoE)−/− mice. Plasma level of sTLT1 was found to be significantly (P<0.05) higher in clinical (2342 ± 184 pg/ml) and subclinical cases (1773 ± 118 pg/ml) than healthy controls (461 ± 57 pg/ml). Moreover, statistical analyses further indicated that sTLT1 was not only associated with common risk factors for Coronary Artery Disease (CAD) in both clinical and subclinical groups but also strongly correlated with disease severity. Ex vivo studies on macrophages showed that sTLT1 interacts with Fcɣ receptor I (FcɣRI) to activate spleen tyrosine kinase (SYK)-mediated downstream MAP kinase signalling cascade to activate nuclear factor-κ B (NF-kB). Activation of NF-kB induces secretion of tumour necrosis factor-α (TNF-α) from macrophage cells that plays pivotal role in governing the persistence of chronic inflammation. Atherosclerotic apoE−/− mice also showed high levels of sTLT1 and TNF-α in nearly occluded aortic stage indicating the contribution of sTLT1 in inflammation. Our results clearly demonstrate that sTLT1 is clinically related to the risk factors of CAD. We also showed that binding of sTLT1 with macrophage membrane receptor, FcɣR1 initiates inflammatory signals in macrophages suggesting its critical role in thrombus development and atherosclerosis.


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