scholarly journals Final height after gonadotropin-releasing hormone agonists with or without growth hormone in Korean girls with central precocious puberty and early puberty

2015 ◽  
Vol 2015 (S1) ◽  
Author(s):  
Eun Byul Kwon ◽  
Young Suk Shim ◽  
Hae Sang Lee ◽  
Hwal Rim Jeong ◽  
Jin Soon Hwang
Keyword(s):  
Growth Hormone ◽  
Precocious Puberty ◽  
Final Height ◽  
Central Precocious Puberty ◽  
Gonadotropin Releasing Hormone ◽  
Early Puberty ◽  
Releasing Hormone

Combined Use of Growth Hormone and Gonadotropin-releasing Hormone Analogues in Precocious Puberty: Theoretic and Practical Considerations

PEDIATRICS ◽  
1999 ◽  
Vol 104 (Supplement_5) ◽  
pp. 1010-1014
Author(s):  
Emily C. Walvoord ◽  
Ora Hirsch Pescovitz
Keyword(s):  
Growth Hormone ◽  
Precocious Puberty ◽  
Adult Height ◽  
Central Precocious Puberty ◽  
Gonadotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Genetic Potential ◽  
Combined Use

The rationale underlying the use of gonadotropin-releasing hormone analogues (GnRHa) to treat patients with central precocious puberty is reviewed. GnRHa are now considered the treatment of choice for patients with central precocious puberty, but the adult heights that these patients attain often fall short of what would be expected according to their genetic potential. This has led to investigations of whether adding growth hormone to GnRHa therapy can improve adult height. The results of recent combination trials are presented and analyzed.

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