A randomized controlled non-inferiority trial of primary care-based facilitated access to an alcohol reduction website (EFAR-FVG): preliminary results

BackgroundChronic Obstructive Airway Disease (COPD) is marked by often severely debilitating exacerbations. Efficient patient-centric research approaches are needed to better inform health management primary-care.AimThe ‘COPE study’ aims to develop a method of predicting COPD exacerbations utilising personal air quality sensors, environmental exposure modelling and electronic health records through the recruitment of patients from consenting GPs contributing to the Clinical Practice Research Datalink (CPRD).MethodThe study made use of Electronic Healthcare Records (EHR) from CPRD, an anonymised GP records database to screen and locate patients within GP practices in Central London. Personal air monitors were used to capture data on individual activities and environmental exposures. Output from the monitors were then linked with the EHR data to obtain information on COPD management, severity, comorbidities and exacerbations. Symptom changes not equating to full exacerbations were captured on diary cards. Linear regression was used to investigate the relationship between subject peak flow, symptoms, exacerbation events and exposure data.ResultsPreliminary results on the first 80 patients who have completed the study indicate variable susceptibility to environmental stressors in COPD patients. Some individuals appear highly susceptible to environmental stress and others appear to have unrelated triggers.ConclusionRecruiting patients through EHR for a study is feasible and allows easy collection of data for long term follow up. Portable environmental sensors could now be used to develop personalised models to predict risk of COPD exacerbations in susceptible individuals. Identification of direct links between participant health and activities would allow improved health management thus cost savings.

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Faculty Opinions recommendation of Optimized antidepressant therapy and pain self-management in primary care patients with depression and musculoskeletal pain: a randomized controlled trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1161063.621527 ◽

2009 ◽

Author(s):

Dan Blazer

Keyword(s):

Primary Care ◽

Randomized Controlled Trial ◽

Musculoskeletal Pain ◽

Controlled Trial ◽

Antidepressant Therapy ◽

Self Management ◽

Randomized Controlled ◽

Primary Care Patients

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Faculty Opinions recommendation of Delivery of evidence-based treatment for multiple anxiety disorders in primary care: a randomized controlled trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3551959.3254057 ◽

2010 ◽

Author(s):

Barbara Rothbaum ◽

Megan Kearns

Keyword(s):

Primary Care ◽

Randomized Controlled Trial ◽

Anxiety Disorders ◽

Controlled Trial ◽

Evidence Based ◽

Evidence Based Treatment ◽

Randomized Controlled

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A Cluster Randomized Controlled Trial of a Stepped-Care Intervention Delivered by Lay Health Workers for Primary Care Patients with Major Depressive Disorder in Nigeria

SSRN Electronic Journal ◽

10.2139/ssrn.3238295 ◽

2018 ◽

Author(s):

Oye Gureje ◽

Bibilola Damilola Oladeji ◽

Alan A. Montgomery ◽

Toyin Bello ◽

Lola Kola ◽

...

Keyword(s):

Primary Care ◽

Health Workers ◽

Controlled Trial ◽

Stepped Care ◽

Lay Health Workers ◽

Major Depressive ◽

Randomized Controlled ◽

Care Intervention ◽

Primary Care Patients ◽

Cluster Randomized

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An Effectiveness Trial of STEADI in an Outpatient, Primary Care Practice

Innovation in Aging ◽

10.1093/geroni/igaa057.2799 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

pp. 774-774

Author(s):

David Rein ◽

Madeleine Hackney ◽

Michele Dougherty ◽

Camille Vaughan ◽

Laurie Imhof ◽

...

Keyword(s):

Primary Care ◽

Medication Review ◽

Primary Care Practice ◽

Controlled Trial ◽

Care Practice ◽

Strength Assessment ◽

Randomized Controlled ◽

Study Team ◽

One Year ◽

The Impact

Abstract The STEADI Options trial uses a randomized, controlled-trial design to assess the effectiveness and cost-effectiveness of the STEADI Initiative . Beginning March, 2020, we will randomize 3,000 adults ≥ 65 years of age at risk for falls seen in an Emory Clinic primary care practice to: (1) full STEADI; (2) a STEADI-derived gait, balance, and strength assessment with physical therapy referrals; (3) a STEADI-derived medication review and management; or (4) usual care. This presentation will discuss decisions made by the study team to facilitate implementation of STEADI including electronically conducting screening prior to the date of encounter, the use of dedicated nursing staff to conduct assessments, implementation of strength, balance, orthostatic hypotension, and vision testing, methods to facilitate medication review, and communication of assessment information to providers. The results from this study will be used to estimate the impact of STEADI on falls, service utilization, and costs over one year.

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