scholarly journals Clinal distribution of human genomic diversity across the Netherlands despite archaeological evidence for genetic discontinuities in Dutch population history

2013 ◽  
Vol 4 (1) ◽  
pp. 9 ◽  
Author(s):  
Oscar Lao ◽  
Eveline Altena ◽  
Christian Becker ◽  
Silke Brauer ◽  
Thirsa Kraaijenbrink ◽  
...  
Keyword(s):  
The Netherlands ◽  
Population History ◽  
Genomic Diversity ◽  
Dutch Population ◽  
Archaeological Evidence ◽  
Human Genomic

scholarly journals The Lifelines COVID-19 Cohort: a questionnaire-based study to investigate COVID-19 infection and its health and societal impacts in a Dutch population-based cohort

2020 ◽  
Author(s):  
Kate Mc Intyre ◽  
Pauline Lanting ◽  
Patrick Deelen ◽  
Henry Wiersma ◽  
Judith M. Vonk ◽  
...  
Keyword(s):  
Risk Factors ◽  
Informed Consent ◽  
The Netherlands ◽  
Disease Susceptibility ◽  
Medical Center ◽  
Dutch Population ◽  
Physical And Mental Health ◽  
Weekly Basis ◽  
Wide Range ◽  
Societal Impacts

AbstractThe COVID-19 pandemic has affected billions of people around the world not only through the infection itself but also through its wider impact on public health and daily life. To assess the effects of the pandemic, a team of researchers across a wide range of disciplines developed and implemented the Lifelines COVID-19 questionnaire, leading to the development of the Lifelines COVID-19 cohort. This cohort is recruited from participants of the Lifelines prospective population cohort and the Lifelines NEXT birth cohort, and participants were asked to fill out detailed questionnaires about their physical and mental health and experiences on a weekly basis starting in late March of 2020 and on a bi-weekly basis staring in June 2020. The Lifelines region covers the three Northern provinces of the Netherlands— Drenthe, Groningen and Friesland—which together account for ∼10% of the Dutch population. To date, >70,000 people have responded to the questionnaires at least once, and the questionnaire program is still ongoing. Data collected by the questionnaires will be used to address four aspects of the outbreak: (1) how the COVID-19 pandemic developed in the three northern provinces of the Netherlands, (2) which environmental risk factors predict disease susceptibility and severity, (3) which genetic risk factors predict disease susceptibility and severity and (4) what are the psychological and societal impacts of the crisis.Informed consentAll Lifelines and Lifelines NEXT participants have provided informed consent that provide the opportunity for add-on research.Research involving human participantsBoth the Lifelines and the Lifelines NEXT studies were approved by the ethics committee of the University Medical Center Groningen.

Tackling radicalization and terrorism in Dutch mental health institutions: Outcomes of a Dutch population survey

2021 ◽  
pp. 229-240
Author(s):  
Carl H.D. Steinmetz
Keyword(s):  
Mental Health ◽  
The Netherlands ◽  
Population Survey ◽  
Health Sector ◽  
Dutch Population ◽  
Health Institutions ◽  
Mental Health Institutions

Virtually no data are available on mental health institutions working on radicalization and terrorism. In the Netherlands we conducted a survey of all mental health institutions (n = 65) in 2016. Fifty-seven per cent responded. The result is that mental health institutions in the Netherlands have started to take small steps towards tacking radicalization and terrorism. These small steps, even by 2016, are a contrast to the reality of radicalization and terrorist incidents and attacks in the Netherlands since 2000. This outcome may have been caused by the resistance of Dutch psychiatrists in the mental health sector (often heard in the Greater Amsterdam region) to the idea that radicalisation and terrorist incidents and attacks are not their work either. For their view is, it is not our job if there is no DSM disorder.

scholarly journals Laboratory surveillance of bacterial gastroenteric pathogens in The Netherlands, 1991–2001

2003 ◽  
Vol 130 (3) ◽  
pp. 431-441 ◽  
Author(s):  
W. van PELT ◽  
M. A. S. de WIT ◽  
W. J. B. WANNET ◽  
E. J. J. LIGTVOET ◽  
M. A. WIDDOWSON ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Young Children ◽  
The Netherlands ◽  
Urban Areas ◽  
Annual Number ◽  
Dutch Population ◽  
Laboratory Surveillance ◽  
Bacterial Gastroenteritis ◽  
General Practices ◽  
The Mean

Results of the Dutch laboratory surveillance of bacterial gastroenteritis between 1991 and 2001 are presented and compared with recent findings in general practices and in the community. Between 1996 and 2000 the mean annual number of stools screened by sentinel laboratories was about 1000 samples/100000 inhabitants, which is 4% of the estimated annual incidence of gastroenteritis in the Dutch population. Campylobacter (36/100000 inhabitants) and salmonella (24/100000 inhabitants) were the main pathogens isolated. Since 1996, the incidence of laboratory confirmed salmonellosis decreased by 30%, predominantly among young children. The incidence of campylobacter was highest in urban areas and Salmonella Enteritidis emerged as the predominant serotype in urban areas. Between 1991 and 2001, multi-resistant Salmonella Typhimurium DT104 emerged to comprise up to 15% of all salmonella isolates in 2001. Reported rates of Shigella spp. and Yersinia spp. varied little, with average annual incidences of 3·2 and 1·2 cases/100000 inhabitants, respectively. Escherichia coli O157 (90% STEC) was scarcely found (0·26/100000).

scholarly journals Environmental Factors Determine Where the Dutch Live: Results From the Netherlands Twin Register

2005 ◽  
Vol 8 (4) ◽  
pp. 312-317 ◽  
Author(s):  
Gonneke Willemsen ◽  
Danielle Posthuma ◽  
Dorret I. Boomsma
Keyword(s):  
Environmental Factors ◽  
The Netherlands ◽  
Genetic Model ◽  
Model Fitting ◽  
Residential Area ◽  
Postal Code ◽  
Young Cohort ◽  
Dutch Population ◽  
Urbanization Level ◽  
Age Cohorts

AbstractThe heritability of the degree of residential area urbanization in twins and their siblings in the Dutch population was examined. The postal code was known for 6879 twins and 2724 siblings registered with the Netherlands Twin Register and born between 1940 and 1983. Using data from Statistics Netherlands (Centraal Bureau voor de Statistiek, 2001), these postal codes could be related to residential area characteristics, including urbanization level. The degree of urbanization was assessed on a 5-point scale: very heavy, heavy, moderate, low and not urbanized. Genetic model-fitting was carried out in three age cohorts: young adults (born 1975 to 1983), adults (born 1965 to 1974) and older adults (born 1940 to1964). Twin and sibling resemblance in urbanization level was expressed in polychoric correlations. These correlations decreased from the youngest cohort (.66 to .86) to the oldest cohort (.20 to .58). In all 3 age cohorts, genetic factors did not contribute to familial resemblance. The influence of common environment decreased in importance from the young cohort (70% to 83%) to the old cohort (46% to 47%) and was lower in women than in men in all but the oldest age cohort. This study did not replicate Australian findings of a genetic contribution in the older cohorts; common environmental factors and, increasingly with age, unique environmental factors determine where the Dutch live. Future studies in European and other populations will reveal whether these results are specific to the Dutch population.

scholarly journals Evidence for medieval salt-making by burning Eel-grass (Zostera marina L.) in the Netherlands

2005 ◽  
Vol 84 (1) ◽  
pp. 43-49 ◽  
Author(s):  
B. van Geel ◽  
G.J. Borger
Keyword(s):  
The Netherlands ◽  
Zostera Marina ◽  
Starting Material ◽  
Northwestern Part ◽  
Land Area ◽  
Archaeological Evidence ◽  
Shallow Marine ◽  
Salt Production ◽  
Marine Habitats ◽  
Peat Deposits

AbstractFrom the 8th/9th centuries onwards the former peat land area in the northwestern part of the Netherlands was drained and reclaimed. Drainage, peat digging and marine erosion of peat deposits created an extension of shallow marine habitats into which Zostera marina (Eel-grass) expanded. Modern publications do not note the use of Eel-grass as starting material for salt-making. Archaeological evidence, however, indicates salt-making activities by using Zostera in medieval times. We postulate that, after salt-containing peat had become difficult to obtain, Eel-grass was used for salt production.

scholarly journals Incidence of AQP4-IgG seropositive neuromyelitis optica spectrum disorders in the Netherlands: About one in a million

2016 ◽  
Vol 2 ◽  
pp. 205521731562565 ◽  
Author(s):  
E Daniëlle van Pelt ◽  
Yu Yi M Wong ◽  
Immy A Ketelslegers ◽  
Dorine AM Siepman ◽  
Dörte Hamann ◽  
...  
Keyword(s):  
The Netherlands ◽  
Neuromyelitis Optica ◽  
Laboratory Data ◽  
Neuromyelitis Optica Spectrum Disorders ◽  
Sensitive Cell ◽  
Dutch Population ◽  
Central Laboratory ◽  
Highly Sensitive ◽  
The Mean ◽  
Spectrum Disorders

Neuromyelitis optica (NMO) is a rare autoimmune disease affecting the optic nerves and spinal cord. In the majority of NMO patients anti-aquaporin-4 antibodies (AQP4-IgG) are detected. Here we assessed a nationwide incidence of AQP4-IgG-seropositive NMO spectrum disorders (NMOSD) in the Netherlands based on results of one central laboratory. Data were collected since the introduction of the highly sensitive cell-based assay for six consecutive years. Samples from 2795 individual patients have been received; of them 94 (3.4%) were seropositive. Based on the Dutch population with 16.6 million inhabitants, the mean incidence of AQP4-IgG-seropositive NMOSD was calculated at 0.09 per 100,000 people.

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