scholarly journals Laboratory surveillance of bacterial gastroenteric pathogens in The Netherlands, 1991–2001

2003 ◽  
Vol 130 (3) ◽  
pp. 431-441 ◽  
Author(s):  
W. van PELT ◽  
M. A. S. de WIT ◽  
W. J. B. WANNET ◽  
E. J. J. LIGTVOET ◽  
M. A. WIDDOWSON ◽  
...  

Results of the Dutch laboratory surveillance of bacterial gastroenteritis between 1991 and 2001 are presented and compared with recent findings in general practices and in the community. Between 1996 and 2000 the mean annual number of stools screened by sentinel laboratories was about 1000 samples/100000 inhabitants, which is 4% of the estimated annual incidence of gastroenteritis in the Dutch population. Campylobacter (36/100000 inhabitants) and salmonella (24/100000 inhabitants) were the main pathogens isolated. Since 1996, the incidence of laboratory confirmed salmonellosis decreased by 30%, predominantly among young children. The incidence of campylobacter was highest in urban areas and Salmonella Enteritidis emerged as the predominant serotype in urban areas. Between 1991 and 2001, multi-resistant Salmonella Typhimurium DT104 emerged to comprise up to 15% of all salmonella isolates in 2001. Reported rates of Shigella spp. and Yersinia spp. varied little, with average annual incidences of 3·2 and 1·2 cases/100000 inhabitants, respectively. Escherichia coli O157 (90% STEC) was scarcely found (0·26/100000).

2016 ◽  
Vol 2 ◽  
pp. 205521731562565 ◽  
Author(s):  
E Daniëlle van Pelt ◽  
Yu Yi M Wong ◽  
Immy A Ketelslegers ◽  
Dorine AM Siepman ◽  
Dörte Hamann ◽  
...  

Neuromyelitis optica (NMO) is a rare autoimmune disease affecting the optic nerves and spinal cord. In the majority of NMO patients anti-aquaporin-4 antibodies (AQP4-IgG) are detected. Here we assessed a nationwide incidence of AQP4-IgG-seropositive NMO spectrum disorders (NMOSD) in the Netherlands based on results of one central laboratory. Data were collected since the introduction of the highly sensitive cell-based assay for six consecutive years. Samples from 2795 individual patients have been received; of them 94 (3.4%) were seropositive. Based on the Dutch population with 16.6 million inhabitants, the mean incidence of AQP4-IgG-seropositive NMOSD was calculated at 0.09 per 100,000 people.


1999 ◽  
Vol 4 (7) ◽  
pp. 81-84 ◽  
Author(s):  
M. L.A. Heijnen ◽  
J W Dorigo-Zetsma ◽  
A I M Bartelds ◽  
B Wilbrink ◽  
M. J.W Sprenger

The Netherlands Institute of Primary Health Care (NIVEL) has coordinated the activities of a sentinel surveillance network of 43 general practices since 1970. These practices care for 1% of the Dutch population, a sample representative of the national pop


2019 ◽  
Author(s):  
Maaike J. C. van den Beld ◽  
Frans A.G. Reubsaet ◽  
Roan Pijnacker ◽  
Airien Harpal ◽  
Sjoerd Kuiling ◽  
...  

Abstract Background: Shigella spp. and entero-invasive Escherichia coli (EIEC) can cause mild diarrhea to dysentery. In the Netherlands, although shigellosis is a notifiable disease, there is no laboratory surveillance for Shigella spp. and EIEC in place. Consequently, the population structure for circulating Shigella spp. and EIEC isolates is not known. This study describes the phenotypic and serological characteristics, the phenotypic and genetic antimicrobial resistance profiles, the virulence gene profiles, the classic multi-locus sequence types (MSLT) and core genome MLST (cgMLST) types, and the epidemiology of Shigella spp. and EIEC isolates collected during a cross-sectional study in the Netherlands in 2016 and 2017. Results: S. sonnei, S. flexneri and EIEC were predominantly detected in the Netherlands. A substantial part of the characterized isolates was resistant to antimicrobials advised for treatment, i.e., 73% was phenotypically resistant to co-trimoxazol and 19% to ciprofloxacin. Antimicrobial resistance was particularly observed in isolates from male patients who had sex with men or from patients that had travelled to Asia. Furthermore, isolates related to international clusters were also circulating in the Netherlands. Travel-related isolates formed clusters with isolates from patients without travel history, indicating their emergence into the Dutch population. Conclusions: In conclusion, laboratory surveillance using whole genome sequencing for genetic characterization of isolates complements the current epidemiological surveillance, as the latter is not sufficient to detect all (inter)national clusters, emphasizing the importance of multifactorial public health approaches.


Author(s):  
Henk Kooi ◽  
Gilles Erkens

Abstract. Local and regional governments in The Netherlands are increasingly faced with the question how to adjust and optimize groundwater table conditions in urban areas to minimize ongoing subsidence and its consequences. To help addressing this question, a model was developed that includes soft-soil deformation by creep. In this paper, a study is presented in which the model was used to investigate and intercompare the effectiveness of measures that (a) prevent anomalous water table drop during a drought, (b) suppress the seasonal variability of the water table, and (c) involve a permanent rise of the mean water table.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Oriel Spierer ◽  
Abraham Spierer

Abstract Background Different surgical methods have been suggested for the correction of intermittent exotropia. Unilateral lateral rectus recession has been described as a surgical alternative for small and moderate-angle exotropia. In general, previous studies did not focus on the outcomes of unilateral lateral rectus recession in young children with intermittent exotropia. The purpose of this study is to evaluate the surgical outcomes of unilateral lateral rectus recession in the treatment of moderate-angle exotropia (≤ 25 PD (prism diopters)) in children. Methods The charts of all patients younger than 12 years of age with moderate-angle exotropia (up to 25 PD) who were operated during the years 2006–2018 were retrospectively reviewed. Fifty-eight patients underwent unilateral lateral rectus recession and had a minimum follow up of 6 months. The angle of exotropia (PD) before and after surgery and the success rate were documented. Results Mean age at surgery was 6.4 ± 1.9 (range 3.5–11.0) years. Exotropia improved from a preoperative angle of 21.4 ± 4.0 PD to 3.5 ± 5.9 PD postoperatively (p < 0.001). Success rate, defined as deviation of ≤ 10 PD, was achieved in 86.2%. There were 2 (3.4%) cases of overcorrection (consecutive esotropia). There were no intra- or postoperative complications. The mean follow-up duration after surgery was 2.3 ± 1.7 years. Conclusions In children with moderate angle exotropia, good postoperative success rate was achieved by performing unilateral lateral rectus recession.


BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e042034
Author(s):  
Tiberiu A Pana ◽  
Sohinee Bhattacharya ◽  
David T Gamble ◽  
Zahra Pasdar ◽  
Weronika A Szlachetka ◽  
...  

ObjectiveWe aimed to identify the country-level determinants of the severity of the first wave of the COVID-19 pandemic.DesignEcological study of publicly available data. Countries reporting >25 COVID-19 related deaths until 8 June 2020 were included. The outcome was log mean mortality rate from COVID-19, an estimate of the country-level daily increase in reported deaths during the ascending phase of the epidemic curve. Potential determinants assessed were most recently published demographic parameters (population and population density, percentage population living in urban areas, population >65 years, average body mass index and smoking prevalence); economic parameters (gross domestic product per capita); environmental parameters (pollution levels and mean temperature (January–May); comorbidities (prevalence of diabetes, hypertension and cancer); health system parameters (WHO Health Index and hospital beds per 10 000 population); international arrivals; the stringency index, as a measure of country-level response to COVID-19; BCG vaccination coverage; UV radiation exposure; and testing capacity. Multivariable linear regression was used to analyse the data.Primary outcomeCountry-level mean mortality rate: the mean slope of the COVID-19 mortality curve during its ascending phase.ParticipantsThirty-seven countries were included: Algeria, Argentina, Austria, Belgium, Brazil, Canada, Chile, Colombia, the Dominican Republic, Ecuador, Egypt, Finland, France, Germany, Hungary, India, Indonesia, Ireland, Italy, Japan, Mexico, the Netherlands, Peru, the Philippines, Poland, Portugal, Romania, the Russian Federation, Saudi Arabia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the UK and the USA.ResultsOf all country-level determinants included in the multivariable model, total number of international arrivals (beta 0.033 (95% CI 0.012 to 0.054)) and BCG vaccination coverage (−0.018 (95% CI −0.034 to –0.002)), were significantly associated with the natural logarithm of the mean death rate.ConclusionsInternational travel was directly associated with the mortality slope and thus potentially the spread of COVID-19. Very early restrictions on international travel should be considered to control COVID-19 outbreaks and prevent related deaths.


Energies ◽  
2021 ◽  
Vol 14 (7) ◽  
pp. 1865
Author(s):  
Bala Bhavya Kausika ◽  
Wilfried G. J. H. M. van Sark

Geographic information system (GIS) based tools have become popular for solar photovoltaic (PV) potential estimations, especially in urban areas. There are readily available tools for the mapping and estimation of solar irradiation that give results with the click of a button. Although these tools capture the complexities of the urban environment, they often miss the more important atmospheric parameters that determine the irradiation and potential estimations. Therefore, validation of these models is necessary for accurate potential energy yield and capacity estimations. This paper demonstrates the calibration and validation of the solar radiation model developed by Fu and Rich, employed within ArcGIS, with a focus on the input atmospheric parameters, diffusivity and transmissivity for the Netherlands. In addition, factors affecting the model’s performance with respect to the resolution of the input data were studied. Data were calibrated using ground measurements from Royal Netherlands Meteorological Institute (KNMI) stations in the Netherlands and validated with the station data from Cabauw. The results show that the default model values of diffusivity and transmissivity lead to substantial underestimation or overestimation of solar insolation. In addition, this paper also shows that calibration can be performed at different time scales depending on the purpose and spatial resolution of the input data.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mohammad Hassan Emamian ◽  
Hossein Ebrahimi ◽  
Hassan Hashemi ◽  
Akbar Fotouhi

Abstract Background Previous studies have reported a high prevalence of hypertension in Iranian students, especially in rural areas. The aim of this study was to investigate the daily intake of salt in students and its association with high blood pressure. Methods A random sub-sample was selected from the participants of the second phase of Shahroud schoolchildren eye cohort study and then a random urine sample was tested for sodium, potassium and creatinine. Urine electrolyte esexcretion and daily salt intake were calculated by Tanaka et al.’s formula. Results Among 1455 participants (including 230 participants from rural area and 472 girls), the mean age was 12.9 ± 1.7 year and the mean daily salt intake was 9.7 ± 2.6 g (95% CI 9.5–9.8). The mean salt consumption in rural areas [10.8 (95% CI 10.4–11.2)] was higher than urban areas [9.4 (95% CI 9.3–9.6)], in people with hypertension [10.8 (95% CI 10.3–11.3)] was more than people with normal blood pressure [9.4 (95% CI 9.3–9.6)], and in boys [9.8 (95% CI 9.7–10.0)] was more than girls [9.3 (95% CI 9.1–9.6)]. Higher age, BMI z-score, male sex and rural life, were associated with increased daily salt intake. Increased salt intake was associated with increased systolic and diastolic blood pressure. Conclusion Daily salt intake in Iranian adolescents was about 2 times the recommended amount of the World Health Organization, was higher in rural areas and was associated with blood pressure. Reducing salt intake should be considered as an important intervention, especially in rural areas.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kaili Yang ◽  
Liyan Xu ◽  
Qi Fan ◽  
Yuwei Gu ◽  
Bo Zhang ◽  
...  

AbstractChina is a populous country but lacks epidemiological data on keratoconus (KC). The present study aimed to investigate the clinical data, demographic data, and visual function (VF) data of KC patients in Central China. A total of 524 KC eyes in 307 KC patients (217 bilateral and 90 unilateral) from Henan Eye Hospital were included in the current study. Demographic and VF data were assessed with questionnaires administered by well-trained staff during face-to-face interviews. Visual acuity value was examined by a qualified optometrist, and the clinical data were measured by professional clinicians. The distributions of sex, residence and education level of KC patients were compared by Chi-square tests, and the ratios of people wearing glasses and rigid gas permeable (RGP) lenses were compared by McNemar tests. General linear models/Chi-squared tests were used to compare the clinical and demographic data according to KC severity. Spearman’s correlation analysis was used to test the associations between the data and KC severity. The mean age at diagnosis was 20.98 ± 6.06 years, and males had a higher ratio of KC than females (P < 0.001). Patients in rural areas had a higher rate of KC than those in urban areas (P = 0.039), and the proportion of KC patients with a higher education level (above high school) was high (P < 0.001). A total of 68.40% of the patients reported eye rubbing and 3.52% had a positive family history. The percentage of people wearing glasses was higher than that of patients wearing RGP lenses (P < 0.001). The total VF score of KC patients was 69.35 ± 15.25. The thinnest corneal thickness (TCT) and stiffness parameter at the first applanation (SP-A1) values were inversely correlated with KC severity (P < 0.05). The mean, steep, and max keratometry (Km, Ks and Kmax) values, the RGP lens use and keratoplasty were positively correlated with KC severity (all P < 0.05). The total VF score of the eye with better VA decreased as the severity increased (r = − 0.21, P = 0.002). The present study comprehensively describes various associated features of KC patients from a tertiary hospital in Central China, providing a reference for understanding the characteristics of KC patients in China.


2021 ◽  
Vol 1 (8) ◽  
Author(s):  
Ymke de Bruijn ◽  
Rosanneke A. G. Emmen ◽  
Judi Mesman

AbstractChildren’s books can create opportunities for children to see themselves as well as others in different settings and stories, but cultural details and specificity within these stories can play an important role in the messages that children take away. Therefore, the present study aims to provide insight in the messages concerning ethnic diversity and various cultures in a subset of popular books that Dutch young children are likely to be exposed to. Books aimed at young children that were sold or borrowed most often or were awarded between 2009 and 2018 in the Netherlands are examined through the combined lens of critical race theory and critical multicultural analysis. Specifically, books including a protagonist or secondary character of color were selected. The study provides insight in the degree of cultural specificity and cultural authenticity, as well as prevailing power relations between characters and ideologies that are portrayed within the books. Results indicate that while cultural stereotypes and ideologies including White supremacy and eurocentrism are found only in a few books, cultural details are generally lacking and colorblindness is common in books aimed at young children. The study therefore underlines the particular need for books that are culturally specific and include authentic cultural details, to improve the reflection of various cultures and experiences of characters of color.


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