The selective α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced inflammation and lung injury

Receptor Agonist ◽

The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation

Molecular Medicine ◽

10.1186/s10020-020-00177-z ◽

2020 ◽

Vol 26 (1) ◽

Cited By ~ 2

Author(s):

Ravikumar A. Sitapara ◽

Alex G. Gauthier ◽

Sergio I. Valdés-Ferrer ◽

Mosi Lin ◽

Vivek Patel ◽

...

Keyword(s):

Lung Injury ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Efficacy and Safety of the α7-Nicotinic Acetylcholine Receptor Agonist ABT-126 in the Treatment of Cognitive Impairment Associated With Schizophrenia

The Journal of Clinical Psychiatry ◽

10.4088/jcp.16m11162 ◽

2018 ◽

Vol 79 (3) ◽

Cited By ~ 3

Author(s):

George M. Haig ◽

Deli Wang ◽

Jun Zhao ◽

Ahmed A. Othman ◽

Earle E. Bain

Keyword(s):

Cognitive Impairment ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Efficacy And Safety ◽

P1-234: Pharmacological and behavioral profile of EVP-5141, a novel α7 nicotinic acetylcholine receptor agonist

Alzheimer s & Dementia ◽

10.1016/j.jalz.2009.04.241 ◽

2009 ◽

Vol 5 (4S_Part_8) ◽

pp. P245-P245

Author(s):

Frank Boess ◽

Jean de Vry ◽

Christina Erb ◽

Timo Flessner ◽

Martin Hendrix ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

Nicotinic Acetylcholine ◽

Behavioral Profile

DOP090 The α7 nicotinic acetylcholine receptor agonist GTS-21 attenuate DSS-induced colitis by improving intestinal mucosal barrier function

Journal of Crohn s and Colitis ◽

10.1093/ecco-jcc/jjx002.127 ◽

2017 ◽

Vol 11 (suppl_1) ◽

pp. S78-S80

Author(s):

H. Zhang ◽

Y. Zhu

Keyword(s):

Acetylcholine Receptor ◽

Barrier Function ◽

Receptor Agonist ◽

Mucosal Barrier ◽

Nicotinic Acetylcholine ◽

Intestinal Mucosal Barrier ◽

Mucosal Barrier Function

α7 Nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced tumour necrosis factor-α production and lung injury

British Journal of Anaesthesia ◽

10.1093/bja/aer202 ◽

2011 ◽

Vol 107 (4) ◽

pp. 559-566 ◽

Cited By ~ 39

Author(s):

M. Kox ◽

J.C. Pompe ◽

E. Peters ◽

M. Vaneker ◽

J.W. van der Laak ◽

...

Keyword(s):

Lung Injury ◽

Tumour Necrosis Factor ◽

Tumour Necrosis ◽

Receptor Agonist ◽

Tumour Necrosis Factor Α ◽

Nicotinic Acetylcholine ◽

Factor Α ◽

Necrosis Factor

GW25-e0163 Selective α7 nicotinic acetylcholine receptor agonist nicotine improves the left ventricular function and the survival of mice infected with coxsackievirus B3

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2014.06.162 ◽

2014 ◽

Vol 64 (16) ◽

pp. C34

Author(s):

Li Yue-Chun ◽

Ge Li-Sha ◽

Zhao Jing-Lin

Keyword(s):

Left Ventricular Function ◽

Ventricular Function ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Coxsackievirus B3 ◽

Left Ventricular ◽

α7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues

British Journal of Pharmacology ◽

10.1038/sj.bjp.0707649 ◽

2008 ◽

Vol 153 (5) ◽

pp. 1054-1061 ◽

Cited By ~ 22

Author(s):

C A Briggs ◽

M R Schrimpf ◽

D J Anderson ◽

E J Gubbins ◽

J H Grønlien ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

The Selective α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide Hydrochloride] Enhances GABAergic Synaptic Activity in Brain Slices and Restores Auditory Gating Deficits in Anesthetized Rats

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.104.076968 ◽

2004 ◽

Vol 312 (3) ◽

pp. 1213-1222 ◽

Cited By ~ 167

Author(s):

M. Hajós ◽

R. S. Hurst ◽

W. E. Hoffmann ◽

M. Krause ◽

T. M. Wall ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

Brain Slices ◽

Synaptic Activity ◽

Nicotinic Acetylcholine ◽

Auditory Gating ◽

Anesthetized Rats

The α7 nicotinic acetylcholine receptor agonist tropisetron counteracts ultraviolet A-mediated oxidative stress in human dermal fibroblasts

Experimental Dermatology ◽

10.1111/exd.13220 ◽

2016 ◽

Vol 25 (12) ◽

pp. 994-996 ◽

Cited By ~ 9

Author(s):

Agatha Stegemann ◽

Markus Böhm

Keyword(s):

Oxidative Stress ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Dermal Fibroblasts ◽

Human Dermal Fibroblasts ◽

Ultraviolet A ◽

Effects of the α7 Nicotinic Acetylcholine Receptor Agonist Gts-21 on the Innate Immune Response in Humans

Shock ◽

10.1097/shk.0b013e3182168d56 ◽

2011 ◽

Vol 36 (1) ◽

pp. 5-11 ◽

Cited By ~ 48

Author(s):

Matthijs Kox ◽

Jan C. Pompe ◽

Marije C. Gordinou de Gouberville ◽

Johannes G. van der Hoeven ◽

Cornelia W. Hoedemaekers ◽

...

Keyword(s):

Immune Response ◽

Acetylcholine Receptor ◽

Innate Immune Response ◽

Receptor Agonist ◽

Innate Immune ◽