scholarly journals Association of TNF-alpha, IL-6 and IL-1beta gene polymorphisms with polycystic ovary syndrome: a meta-analysis

BMC Genetics ◽  
2015 ◽  
Vol 16 (1) ◽  
pp. 5 ◽  
Author(s):  
Renyong Guo ◽  
Ying Zheng ◽  
Jiezuan Yang ◽  
Nengneng Zheng
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Gene Polymorphisms ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Tnf Alpha ◽  
Ovary Syndrome

scholarly journals Association of DENND1A Gene Polymorphisms with Polycystic Ovary Syndrome: A Meta-Analysis

2016 ◽  
Vol 8 (2) ◽  
pp. 135-143 ◽  
Author(s):  
Shan Bao ◽  
Jun-Hong Cai ◽  
Shu-Ying Yang ◽  
Yongchao Ren ◽  
Tian Feng ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Gene Polymorphisms ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Ovary Syndrome

Associations of adiponectin gene polymorphisms with polycystic ovary syndrome: a meta-analysis

Endocrine ◽  
2012 ◽  
Vol 42 (2) ◽  
pp. 299-306 ◽  
Author(s):  
Hongxia Jia ◽  
Lili Yu ◽  
Xuxiao Guo ◽  
Wei Gao ◽  
Zhaoshun Jiang
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Gene Polymorphisms ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Adiponectin Gene ◽  
Ovary Syndrome

scholarly journals Association between VEGF gene polymorphisms (11 sites) and polycystic ovary syndrome risk

2020 ◽  
Vol 40 (3) ◽  
Author(s):  
Li Huang ◽  
Lunwen Wang
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Gene Polymorphisms ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Critical Role ◽  
Reproductive Function ◽  
Vegf Gene ◽  
Case Control Studies ◽  
Ovary Syndrome ◽  
Endothelial Growth Factor

Abstract Vascular endothelial growth factor (VEGF) plays a critical role in ovarian folliculogenesis and normal reproductive function. So far, several studies focusing on association between VEGF gene polymorphisms and polycystic ovary syndrome (PCOS). However, above association between the VEGF gene polymorphisms and PCOS susceptibility is uncertain. Hence, we performed a timely meta-analysis containing all current publications to make clear this relationship. We searched articles from the PubMed, Embase and Chinese language (WanFang and CNKI) databases that were published up until May 10, 2019. Finally, we obtained 9 studies, containing 29 case–control studies and 11 different polymorphisms. The odds ratios (OR) and 95% confidence intervals (CI) were revealed association strengths. There were significantly decreased associations between rs2010963 (-634), +9812, +405 polymorphisms and PCOS risk. Nevertheless, there existed increased associations between rs699947 (-2578), rs833061, rs1570360 (-1154), rs3025020, rs3025039 polymorphisms and PCOS susceptibility. Our current analysis suggested VEGF gene polymorphisms may be associated with PCOS risk, which is possible to be expected to become biomarkers of early detection for women.

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