Epidemiological and clinical profiles of acute poisoning in patients admitted to the intensive care unit in eastern Iran (2010 to 2017)

Background: Hong Kong Poison Information Centre publishes annual reports on all poisoning cases received by the Centre in that year since 2006. However, there is little data about acute poisoning cases requiring intensive care unit admissions in Hong Kong. Objective: To report and analyze the 10-year poisoning data of acute poisoning patients presenting to an Accident and Emergency Department requiring intensive care in a regional hospital of Hong Kong. Methods: This was a retrospective study on patients presented from January 2007 to December 2016. These cases were retrieved from Clinical Data Analysis and Reporting System of the Hospital Authority, Hong Kong. Clinical data of these cases were then retrieved from patients’ electronic records. Results: A total of 270 cases were analyzed during the period. There were 152 (56.3%) male patients and 118 (43.7%) female patients. The middle aged group (age 30–39 and age 40–49) constitutes nearly half (48.6%) of all these admissions. Around 50% of them had history of psychiatric illness. Nearly 40% of them were known substance abusers. Majority of the patients (66.7%) were admitted directly from Accident and Emergency Department. The commonest cause was suspected self-harm (56.3%). When ethanol (13%) was excluded, the five commonest types of poisons were benzodiazepine (26.3%), opioids (20.7%), zopiclone (18.5%), carbon monoxide poisoning (13%), and household products (10.7%). Twenty-seven patients (10%) had decontamination done in Accident and Emergency Department or Emergency Medicine Ward. 112 patients (41.5%) were given one or more antidotes in Accident and Emergency Department and Emergency Medicine Ward. Altered mental status was the most frequently found complications (72.2%) in these patients. 76 patients (28.1%) required endotracheal intubation in Accident and Emergency Department. The length of stay in Intensive Care Unit ranged from 1 to 7 days with an average of 2.1 days. There were 25 deaths (9.3%) and 31 patients with major effects (11.5%). Conclusion: An estimate of 9.4% of acute poisoning patients presenting to Accident and Emergency Department might need Intensive Care Unit care at certain stage of their hospital stay. Benzodiazepine, opioids, zopiclone, carbon monoxide poisoning, and ethanol were the top five poisons in our series from 2007 to 2016. The mortality rate (9.3%) was high in our series given that there were more substance abusers.

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Acinetobacter infections in a tertiary level intensive care unit in northern India: Epidemiology, clinical profiles and outcomes

Journal of Infection and Public Health ◽

10.1016/j.jiph.2011.12.002 ◽

2012 ◽

Vol 5 (2) ◽

pp. 145-152 ◽

Cited By ~ 4

Author(s):

Ashu Sara Mathai ◽

Aroma Oberoi ◽

Sheeba Madhavan ◽

Parmdeep Kaur

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Tertiary Level ◽

Northern India ◽

Clinical Profiles

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Clinical profile and outcome of patients with acute poisoning admitted in intensive care unit of tertiary care center in Eastern Nepal

Indian Journal of Critical Care Medicine ◽

10.4103/ijccm.ijccm_207_18 ◽

2018 ◽

Vol 22 (10) ◽

pp. 691-696

Author(s):

Lalit Rajbanshi ◽

Batsalya Arjyal ◽

Rakesh Mandal

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Care Center ◽

Tertiary Care ◽

Acute Poisoning ◽

Clinical Profile ◽

Tertiary Care Center

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Over 8 years experience on severe acute poisoning requiring intensive care in Hong Kong, China

Human & Experimental Toxicology ◽

10.1177/0960327110361753 ◽

2010 ◽

Vol 29 (9) ◽

pp. 757-765 ◽

Cited By ~ 25

Author(s):

Sin-Man Lam ◽

Arthur Chun-Wing Lau ◽

Wing-Wa Yan

Keyword(s):

Intensive Care Unit ◽

Hong Kong ◽

Intensive Care ◽

Alcohol Intoxication ◽

Acute Poisoning ◽

Tricyclic Antidepressant ◽

Psychiatric Ward ◽

Intensive Care Admission ◽

Lengths Of Stay ◽

Overall Mortality

In order to obtain up-to-date information on the pattern of severe acute poisoning and the characteristics and outcomes of these patients, 265 consecutive patients admitted to an intensive care unit in Hong Kong for acute poisoning from January 2000 to May 2008 were studied retrospectively. Benzodiazepine (25.3%), alcohol (23%), tricyclic antidepressant (17.4%), and carbon monoxide (15.1%) were the four commonest poisons encountered. Impaired consciousness was common and intubation was required in 67.9% of admissions, with a median duration of mechanical ventilation of less than 1 day. The overall mortality was 3.0%. Among the 257 survivors, the median lengths of stay in the intensive care unit and acute hospital (excluding days spent in psychiatric ward and convalescent hospital) were less than 1 day and 3 days, respectively. Factors associated with a longer length of stay included age of 65 or older, presence of comorbidity, Acute Physiology and Chronic Health Evaluation II score of 25 or greater, and development of shock, rhabdomyolysis, and aspiration pneumonia, while alcohol intoxication was associated with a shorter stay. This is the largest study of its kind in the Chinese population and provided information on the pattern of severe acute poisoning requiring intensive care admission and the outcomes of the patients concerned.

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Clinical Profile and Prognostication in Patients Admitted at Medical Intensive Care Unit at B. P. Koirala Institute of Health Sciences

Birat Journal of Health Sciences ◽

10.3126/bjhs.v4i3.27040 ◽

2020 ◽

Vol 4 (3) ◽

pp. 855-858

Author(s):

Puru Koirala ◽

Narendra Bhatta ◽

Ram Hari Ghimire ◽

Deebya Raj Mishra ◽

Bidesh Bidesh Bista

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Sequential Organ Failure Assessment ◽

Organ Failure ◽

Medical Intensive Care Unit ◽

Health Sciences ◽

Assessment Score ◽

Failure Assessment ◽

Clinical Profiles ◽

Medical Intensive Care

Introduction: Critical Care management is an important issue in developing countries where Medical Intensive Care Units (MICU) patients have comorbidity or complications of multisystem involvement. Objectives: The objective of study was to analyze clinical profiles of patients in Medical Intensive Care Unit and identify applicable factors that prognosticate outcomes. Methodology: Study conducted at Medical Intensive Care Unit of B. P. Koirala Institute of Health Sciences, Dharan, Nepal. Records from July 31, 2013 to August 1, 2014 were retrospectively studied. Clinical profiles were analyzed, outcomes defined as improved, referred, Leave Against Medical Advice (LAMA) or death. An online calculator (MD+Calc) was used to calculate Sequential Organ Failure Assessment Score (SOFA). Descriptive statistics were used, values <0.05 were statistically significant. Results: Of 70 patients 36 (51.4%) were female, 30 (42.9%) had sepsis of which 12 (40%) had Community-Acquired Pneumonia. 8 (11.43%) had Acute Respiratory Distress Syndrome, 7 (10%) had congestive cardiac failure. 43 (61.43%) improved, 17 (24.3%) expired, 9 (12.86%) LAMA, one patient was referred. Sequential Organ Failure Assessment Score was >9 in 23 (41.07%) cases. Of 17 expired cases, 14 (82.35%) had SOFA score >9. Conclusion: Sepsis with pulmonary involvement is primary diagnosis in patients requiring Medical Intensive Unit Care. Sequential Organ Failure Assessment Score was useful for prognostication and can be used for better clinical decision-making.

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