scholarly journals Analysis of individual and clinical factors in acute poisoning cases in the intensive care unit

2014 ◽  
Vol 2 (3) ◽  
pp. 101
Author(s):  
Cevdet Düger ◽  
İclal Özdemir Kol ◽  
Koray Ak ◽  
Ahmet Cemil İşbir ◽  
Sinan Gürsoy ◽  
...  
2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Javier Pemán ◽  
◽  
Rafael Zaragoza ◽  
Guillermo Quindós ◽  
Miriam Alkorta ◽  
...  

2021 ◽  
Vol 9 ◽  
Author(s):  
Yueniu Zhu ◽  
Xiaodong Zhu ◽  
Lili Xu ◽  
Mengyan Deng

Objective: End-of-life(EOL) care decision-making for infants and children is a painful experience. The study aimed to explore the clinical factors influencing the EOL care to withhold/withdraw life-sustaining treatment (WLST) in Chinese pediatric intensive care unit (PICU).Methods: A 14-year retrospective study (2006–2019) for pediatric patients who died in PICU was conducted. Based on the mode of death, patients were classified into WLST group (death after WLST) and fCPR group (death after full intervention, including cardiopulmonary resuscitation). Intergroup differences in the epidemiological and clinical factors were determined.Results: There were 715 patients enrolled in this study. Of these patients, 442 (61.8%) died after WLST and 273 (38.2%) died after fCPR. Patients with previous hospitalizations or those who had been transferred from other hospitals more frequently chose WLST than fCPR (both P < 0.01), and the mean PICU stay duration was significantly longer in the WLST group (P < 0.05). WLST patients were more frequently complicated with chronic underlying disease, especially tumor (P < 0.01). Sepsis, diarrhea, and cardiac attack (all P < 0.05) were more frequent causes of death in the fCPR group, whereas tumor as a direct cause of death was more frequently seen in the WLST group. Logistic regression analysis demonstrated that previous hospitalization and underlying diseases diagnosed before admission were strongly associated with EOL care with WLST decision (OR: 1.6; P < 0.05 and OR: 1.6; P < 0.01, respectively).Conclusions: Pediatric patients with previous hospitalization and underlying diseases diagnosed before admission were associated with the EOL care to WLST.


2018 ◽  
Vol 26 (1) ◽  
pp. 3-14
Author(s):  
Fu Ng

Background: Hong Kong Poison Information Centre publishes annual reports on all poisoning cases received by the Centre in that year since 2006. However, there is little data about acute poisoning cases requiring intensive care unit admissions in Hong Kong. Objective: To report and analyze the 10-year poisoning data of acute poisoning patients presenting to an Accident and Emergency Department requiring intensive care in a regional hospital of Hong Kong. Methods: This was a retrospective study on patients presented from January 2007 to December 2016. These cases were retrieved from Clinical Data Analysis and Reporting System of the Hospital Authority, Hong Kong. Clinical data of these cases were then retrieved from patients’ electronic records. Results: A total of 270 cases were analyzed during the period. There were 152 (56.3%) male patients and 118 (43.7%) female patients. The middle aged group (age 30–39 and age 40–49) constitutes nearly half (48.6%) of all these admissions. Around 50% of them had history of psychiatric illness. Nearly 40% of them were known substance abusers. Majority of the patients (66.7%) were admitted directly from Accident and Emergency Department. The commonest cause was suspected self-harm (56.3%). When ethanol (13%) was excluded, the five commonest types of poisons were benzodiazepine (26.3%), opioids (20.7%), zopiclone (18.5%), carbon monoxide poisoning (13%), and household products (10.7%). Twenty-seven patients (10%) had decontamination done in Accident and Emergency Department or Emergency Medicine Ward. 112 patients (41.5%) were given one or more antidotes in Accident and Emergency Department and Emergency Medicine Ward. Altered mental status was the most frequently found complications (72.2%) in these patients. 76 patients (28.1%) required endotracheal intubation in Accident and Emergency Department. The length of stay in Intensive Care Unit ranged from 1 to 7 days with an average of 2.1 days. There were 25 deaths (9.3%) and 31 patients with major effects (11.5%). Conclusion: An estimate of 9.4% of acute poisoning patients presenting to Accident and Emergency Department might need Intensive Care Unit care at certain stage of their hospital stay. Benzodiazepine, opioids, zopiclone, carbon monoxide poisoning, and ethanol were the top five poisons in our series from 2007 to 2016. The mortality rate (9.3%) was high in our series given that there were more substance abusers.


2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Omid Mehrpour ◽  
Ayob Akbari ◽  
Firoozeh Jahani ◽  
Alireza Amirabadizadeh ◽  
Elaheh Allahyari ◽  
...  

2010 ◽  
Vol 29 (9) ◽  
pp. 757-765 ◽  
Author(s):  
Sin-Man Lam ◽  
Arthur Chun-Wing Lau ◽  
Wing-Wa Yan

In order to obtain up-to-date information on the pattern of severe acute poisoning and the characteristics and outcomes of these patients, 265 consecutive patients admitted to an intensive care unit in Hong Kong for acute poisoning from January 2000 to May 2008 were studied retrospectively. Benzodiazepine (25.3%), alcohol (23%), tricyclic antidepressant (17.4%), and carbon monoxide (15.1%) were the four commonest poisons encountered. Impaired consciousness was common and intubation was required in 67.9% of admissions, with a median duration of mechanical ventilation of less than 1 day. The overall mortality was 3.0%. Among the 257 survivors, the median lengths of stay in the intensive care unit and acute hospital (excluding days spent in psychiatric ward and convalescent hospital) were less than 1 day and 3 days, respectively. Factors associated with a longer length of stay included age of 65 or older, presence of comorbidity, Acute Physiology and Chronic Health Evaluation II score of 25 or greater, and development of shock, rhabdomyolysis, and aspiration pneumonia, while alcohol intoxication was associated with a shorter stay. This is the largest study of its kind in the Chinese population and provided information on the pattern of severe acute poisoning requiring intensive care admission and the outcomes of the patients concerned.


2020 ◽  
Author(s):  
Min Kyoon Kim ◽  
Yoo Shin Choi ◽  
Suk-Won Suh ◽  
Hyun Kang

Abstract BackgroundAdequate nutritional therapy in critically ill patients is integral to an optimal outcome. This study determined which clinical factors affect the target calorie approach during SICU admission.MethodsConsecutive patients that were provided with nutritional support during their hospitalization in the Chung-Ang university hospital SICU from August 2014 to July 2016 were included in this retrospective study. Data on demographics, supplied calorie amount and method, lengths of stay in the hospital and the intensive care unit, and mortality outcomes when discharged from the SICU were collected and analyzed. ResultsIn 279 patients, 36.9% approached target calorie intake during SICU stay. In multivariate regression analysis, patients’ sex and nasogastric tube insertion were significant factors affecting target calorie approach. (OR 2.00 for female sex, 2.03 for nasogastric tube insertion; p-value 0.012 and 0.024 for each, respectively) When we divide the patients into two groups by SICU stay length, nasogastric tube insertion is more important variable in ≤7days of SICU stay for achieve the target calorie goal. (OR 4.13; p-value 0.006) As higher amounts of calories are supplied to the patients, total lymphocyte count (TLC) and C-reactive protein (CRP) levels improved significantly without changes in mortality.ConclusionExistence of nasogastric tube and patient sex were important clinical factors to reach target calorie supply for SICU patients and their importance is different according to SICU stay length.


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