scholarly journals Lactoferrin amyloid presenting as a mural nodule in a pancreatic cystic lesion prompting pancreatoduodenectomy: a case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Katherine A. Baugh ◽  
Svetang Desai ◽  
George Van Buren 2nd ◽  
William E. Fisher ◽  
Carlos A. Farinas ◽  
...  
Keyword(s):  
Case Report ◽  
Cystic Lesion ◽  
Amyloid Deposition ◽  
Mural Nodule ◽  
Histological Evaluation ◽  
Cystic Lesions ◽  
First Case ◽  
Rare Occasion ◽  
Mucinous Cyst ◽  
Mural Nodules

Abstract Background Amyloid deposition in pancreas is rare. Lactoferrin amyloid deposition has not been reported in pancreas, till date. Presence of enhancing mural nodule in a cyst on imaging is a worrisome feature for malignancy, and warrants surgical resection in a surgically fit candidate, as per Fukuoka guidelines for management of cystic lesions in pancreas. Case report We report a case of localized amyloidosis presenting as a mural nodule in a 1.6 cm cyst located in the head of pancreas, which led to pancreatoduodenectomy in a 69 year old woman. Histological evaluation revealed a simple mucinous cyst with localized lactoferrin amyloid deposition corresponding to the mural nodule identified on imaging. Conclusions We report the first case of localized lactoferrin amyloid deposition in pancreas that presented as a mural nodule in a cystic lesion and prompted pancreatoduodenectomy. This unique case illustrates that on rare occasion mural nodule in a cyst can be benign. It adds amyloid deposition to the differential diagnosis of mural nodules in pancreatic cystic lesions seen on imaging.

scholarly journals Adrenal Ganglioneuroma with Multifocal Retroperitoneal Extension: A Challenging Diagnosis

2011 ◽  
Vol 11 ◽  
pp. 1548-1553 ◽  
Author(s):  
Marco Oderda ◽  
Elena Cattaneo ◽  
Francesco Soria ◽  
Antonella Barreca ◽  
Luigi Chiusa ◽  
...  
Keyword(s):  
Case Report ◽  
Nervous Tissue ◽  
Rare Case ◽  
Histological Evaluation ◽  
Adrenal Incidentalomas ◽  
Complete Excision ◽  
First Case ◽  
Neuroblastic Tumors ◽  
Sympathetic Nervous ◽  
Adrenal Ganglioneuroma

A ganglioneuroma (GN) is the rarest and most benign of the neuroblastic tumors and originates from neural crest cells wherever sympathetic nervous tissue exists, such as in the retroperitoneum and adrenal gland. The diagnosis can be very challenging, given the rarity and asymptomatic presentation of this neoplasia, and can be achieved only by means of histological evaluation. Although benign, a few cases of metastatic GNs have been reported in the literature. The prognosis, however, seems to be excellent after surgical resection. We describe a rare case of multifocal retroperitoneal GN, diagnosed incidentally in a 46-year-old woman, with para-aortic and adrenal localizations. After intraoperative pathological diagnosis was made, complete excision of all the visible masses was performed. The postoperative period was uneventful and she was recurrence free 3 months after surgery. To our knowledge, this is the first case report of a multifocal retroperitoneal GN. Among the broad differential diagnoses of adrenal incidentalomas, an adrenal location of neuroblastic tumors should not be forgotten.

Lymphoepithelial cyst of the pancreas. A case report

2007 ◽  
Vol 52 (3) ◽  
pp. 53-53
Author(s):  
L Fraser ◽  
OO Komolafe ◽  
JR Anderson
Keyword(s):  
Case Report ◽  
Cystic Lesion ◽  
Cystic Lesions ◽  
Lymphoepithelial Cyst ◽  
Invasive Procedures ◽  
Diagnostic Challenge ◽  
Distal Pancreas ◽  
Ct And Mri ◽  
Diagnostic Investigations ◽  
The Ideal

We present the case of a 63 year-old male who presented with a cystic lesion of the distal pancreas. Excision and histology showed this to be a lymphoepithelial cyst. Cystic lesions of the pancreas represent a diagnostic challenge, especially when pseudocyst secondary to pancreatitis is excluded. These lesions can be broadly classified into benign, pre-malignant and malignant. Widely used imaging modalities such as CT and MRI are not able to categorically differentiate between these. More invasive procedures such as endoscopic US and FNA again do not give a cast-iron diagnosis. Our patient had a symptomatic cystic lesion in his pancreas which was excised after cross-specialty discussion. We advocate that this is the ideal way to treat patients with cystic lesions of the pancreas, with each case considered on its own merits as all current diagnostic investigations have their limitations.

scholarly journals Cystic lesions of pancreas: challenges in diagnosis and management

2016 ◽  
Vol 18 (3) ◽  
pp. 53
Author(s):  
S Bohara ◽  
TY Tamang ◽  
DK Maharjan ◽  
SK Shrestha ◽  
PB Thapa
Keyword(s):  
Cystic Lesion ◽  
Mucinous Cystadenoma ◽  
Pancreatic Head ◽  
College Teaching ◽  
Serous Cystadenoma ◽  
Pancreatic Tumors ◽  
Pancreatic Cysts ◽  
Cystic Lesions ◽  
Pancreatic Cystic Lesion ◽  
First Case

Introduction: Pancreatic cysts are common (2.5%). Cystic neoplasms represent 10% of cystic lesions and 1% of pancreatic tumors. However, it is difficult to differentiate benign cyst from malignant cystic lesions preoperatively.Objective: To study the cases of pancreatic cystic lesion who underwent various forms of pancreatic resection.Materials and Methods: Nine cases of pancreatic cystic lesion who presented to Kathmandu Medical College Teaching Hospital, Surgical Unit 3 within December 2014- November 2015 were evaluated. Four pancreatic cysts who underwent resection are discussed whereas not managed with resection are excluded.Results: There were 4 cases of pancreatic cyst who underwent pancreatic resection. First case underwent pancreaticoduodenectomy for pancreatic mucinous cystadenoma. However histopathological examination revealed a serous cystadenoma. In second case, pancreatic neck lesion suspected to be mucinous cystadenoma or pseudocyst in MRCP, with negative malignant cells in EUS guided FNAC underwent Central pancreatectomy and was found to be serous cystadenoma. The third case with suspected pseudocyst underwent Pancreaticoduodenectomy after a 3X2 cm2 cystic mass was felt at the posteroinferior side of pancreatic head and malignancy was suspected intraoperatively . HPE report was mucinous cystadenoma. The fourth case with pancreatic pseudocyst at tail with duct calculi and chronic pancreatitis underwent distal pancreatectomy with splenectomy with Frey’s procedure.Conclusion: Management of pancreatic cystic lesion is challenging. Though radiological imaging has limited role in accurate diagnosis, endoscopic ultrasound may be of some benefit.

scholarly journals A Case Report of An Iris Epithelial Cyst Masquerading As Iris Cysticercosis

2020 ◽  
Vol 12 (1) ◽  
pp. 114-118
Author(s):  
Abhishek Hoshing ◽  
Rita Dhamankar ◽  
Shabnam Tanwar ◽  
Deepak Bhat
Keyword(s):  
Case Report ◽  
Cystic Lesion ◽  
Histopathological Examination ◽  
Ultrasound Biomicroscopy ◽  
Cystic Lesions ◽  
Epithelial Cyst ◽  
Pigment Epithelial ◽  
The Right

Introduction: Iris cysts can be primary or secondary. It is common to mistake a parasitic cyst for a benign pigment epithelial cyst. However, we report a case where a benign cyst was mistaken for a parasitic cyst. Case: A 50-year-old gentleman was seen in our OPD with gradual, progressive, painless diminution of vision in the right eye over past 5 Months. He was found to have a cystic lesion in the iris encroaching upon the pupil. Observations: Ultrasound biomicroscopy showed features characteristic of cysticercosis. In-toto excision of the cyst was done and was sent for histopathological examination. Histopathology failed to reveal features consistent with cysticercosis and instead showed characteristics of epithelial cyst of the iris. Conclusion: Histopathological examination should be done for all cystic lesions of the iris to confirm diagnosis.

scholarly journals Idiopathic seasonal alopecia in horse: case report

2020 ◽  
Vol 72 (2) ◽  
pp. 431-436
Author(s):  
A.F. Souza ◽  
J. Schade ◽  
M.S. Casa ◽  
S.D. Traverso ◽  
J.H. Fonteque
Keyword(s):  
Case Report ◽  
Hair Growth ◽  
Inflammatory Infiltrate ◽  
Clinical Signs ◽  
Hair Shaft ◽  
Hair Follicles ◽  
Histological Evaluation ◽  
Unknown Etiology ◽  
First Case

ABSTRACT This report describes the first case of idiopathic seasonal alopecia in a horse in Brazil. The disease is of unknown etiology, characterized by alopecic processes in the thoracic and lateral abdominal regions, in a bilaterally symmetrical way. An eight-year-old male grade horse was treated presenting hair loss in a bilaterally symmetrical manner in the arm and abdomen areas, without any other associated clinical signs. The areas with alopecia showed no pruritus, inflammation or scaling. On the epidermis, the histological evaluation presented irregular hyperplasia, hyperpigmentation, compact orthokeratosis, edema and an inflammatory infiltrate. The hair follicles were active and containing hair shaft. The case was monitored with photographic records for two consecutive years (2012 to 2014), in which the hair fall occurred at the end of autumn with spontaneous hair growth in the middle of the summer. The diagnosis was based on the history, histopathology and photographic follow-up performed. Although mentioned in the literature, this is the first clinical and pathological description of such disorder affecting an equine in Brazil.

scholarly journals Benign Mucinous Tumor of Ovary with a Sarcoma-Like Mural Nodule: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-2
Author(s):  
Sailabala Garikaparthi ◽  
Renuka Inuganti Venkata ◽  
Krishna Bharathi Yarlagadda ◽  
Annapurna Parvatala
Keyword(s):  
Case Report ◽  
Ovarian Tumor ◽  
Anaplastic Carcinoma ◽  
Mural Nodule ◽  
Mucinous Tumor ◽  
Middle Aged ◽  
Worse Prognosis ◽  
Mural Nodules

Sarcoma-like mural nodules occur predominantly in middle-aged women. Distinction of these lesions from true sarcomatous nodules and foci of anaplastic carcinoma is important because of the worse prognosis of these tumors in comparison with the favorable behavior of sarcoma-like mural nodules. In this report we describe the case of a 35-year-old woman with a mucinous ovarian tumor having a mural nodule in the wall.

scholarly journals Abdominal Wall Hydatid Cyst: Case Report and Review of Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
V. Abhishek ◽  
Vijayraj S. Patil ◽  
Ullikashi Mohan ◽  
B. S. Shivswamy
Keyword(s):  
Case Report ◽  
Hydatid Cyst ◽  
Abdominal Wall ◽  
Cystic Lesion ◽  
Cystic Lesions ◽  
Review Of Literature ◽  
Surgical Exploration ◽  
One Year

A 60-year-old woman presented with a swelling in right paraumbilical region of one-year duration. Examination revealed a painless cystic swelling 15 × 10 cm with cough impulse. Ultrasound and CECT abdomen showed a subcutaneous cystic swelling with intramuscular extension. No other intraabdominal cystic lesions were found. Surgical exploration showed a cystic lesion adherent to peritoneum without any intraperitoneal extension. Cyst was carefully excised without any spillage. Gross specimen on opening showed multiple daughter cysts consistent with hydatid cyst, confirming the diagnosis of solitary abdominal wall hydatid cyst.

scholarly journals NON-SURGICAL MANAGEMENT OF A LARGE CYSTIC LESION WITH SURGICAL DECOMPRESSION: A CASE REPORT WITH 14 MONTHS FOLLOW UP

2021 ◽  
Vol 9 (02) ◽  
pp. 265-272
Author(s):  
Shwetank Shrivastava ◽  
◽  
Ashish K. Jain ◽  
Rahul D. Rao ◽  
Meenakshi Verma ◽  
...  
Keyword(s):  
Case Report ◽  
Root Canal ◽  
Cystic Lesion ◽  
Case Reports ◽  
Root Canal Treatment ◽  
Cystic Lesions ◽  
Saline Irrigation ◽  
Periapical Lesions ◽  
Apical Surgery

The main aim of this case report was to report the clinical efficacy of decompression for treating large periapical lesions. Tooth with large periapical cystic lesions were treated with decompression after root canal treatment. A conventional decompression technique such as aspiration/irrigation technique was used in this case. An 18-G needle with a syringe was used to aspirate the cystic lesion. Two needles were then inserted into the lesion copious saline irrigation was delivered from 1 needle and until clear saline was expressed from the other. Complete enucleation and root-end surgery was not done in the case. Healed lesions or lesions in healing were observed after 14 months. On the basis of the presented case and published case reports regarding large periapical cystic lesions, conservative decompression may be used for certain cases before or in lieu of apical surgery. Decompression enables healing of large, persistent periapical lesions after root canal treatment.

scholarly journals Clival simple bone cyst: Rare pathological entity (case report)

2020 ◽  
Vol 11 ◽  
pp. 427
Author(s):  
Jumana Abdulmohsen Fatani ◽  
Alaa Arab ◽  
Hisham Alkhalidi ◽  
Abdulrazag Ajlan
Keyword(s):  
Case Report ◽  
Arachnoid Cyst ◽  
Cystic Lesion ◽  
Bone Cyst ◽  
Cystic Lesions ◽  
Bone Cysts ◽  
Case Description ◽  
Simple Bone Cyst ◽  
Large Size ◽  
Neoplastic Process

Background: Clival cystic lesions are not frequently seen in neurosurgery. Cystic lesion in the clivus can be part of a neoplastic process such as chordoma, chondrosarcoma, plasmacytoma, or metastasis. Rare types of pure cystic clival lesions include simple bone cysts and arachnoid cysts, which are asymptomatic most of the time and do not cause symptoms until they reach a large size. Case Description: This is a case report of a healthy 53-year-old male patient with a clival cystic lesion. The patient underwent surgical drainage and wall resection of the clival lesion with no postoperative complications. Intraoperative finding raised the possibility of the diagnosis of an arachnoid cyst. However, the pathology findings indicated a simple bone cyst. Conclusion: Simple bone cyst and arachnoid cyst in the clivus are rare, they should be considered in the diagnosis of clival cystic lesions.

The first case report of Pembrolizumab inducing thyroiditis and hypophysitis

2020 ◽  
Author(s):  
Rahman Maraqa Sima Abdel ◽  
Robert McMahon ◽  
Anusha Pinjala ◽  
Gastelum Alheli Arce ◽  
Mohsen Zena
Keyword(s):  
Case Report ◽  
First Case
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