scholarly journals Study on the pathogenesis of Holmes tremor by multimodal 3D medical imaging: case reports of three patients

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Min Shi ◽  
Anrong Wang ◽  
Yu Fang ◽  
Jun Guo ◽  
Zhaoying Li ◽  
...  

Abstract Background We examined for the first time the imaging characteristics of Holmes tremor (HT) through multimodal 3D medical imaging. Case presentation Three patients with Holmes tremor who visited the Affiliated Hospital of Chengdu University of TCM from August 2018 to April 2021 were retrospectively investigated to summarize their clinical and imaging data. Results Holmes tremor in two of the three patients was caused by hypertensive cerebral hemorrhage and in the third patient induced by hemorrhage due to ruptured brain arteriovenous malformations. HT occurred 1 to 24 months after the primary disease onset and manifested as a tremor in the contralateral limb, mostly in the upper portion. Cranial MRI showed that the lesions involved the thalamus in all three patients. The damaged thalamic nuclei included the ventral anterior nucleus, ventral lateral nucleus and ventromedial lateral nucleus, and the damaged nerve fibers included left thalamocortical tracts in one patient. In the other two patients, the damaged thalamic nuclei included the centromedian and dorsomedial nucleus, and the damaged nerve fibers included left cerebellothalamic and thalamocortical tracts. One patient showed significant improvement after treatment with pramipexole while the other two patients exhibited a poor response, one of whom had no response to the treatment with pramipexole and was only significantly relieved by clonazepam. Conclusion We used multimodal 3D medical imaging for the first time to analyze the pathogenesis of HT and found that multiple thalamic nuclei were damaged. The damaged nuclei and nerve fiber tracts of two patients were different from those of the third patient, with different clinical manifestations and therapeutic effects. Therefore, it is speculated that there may be multiple pathogeneses for HT.

1963 ◽  
Vol 6 (03) ◽  
pp. 30-31
Author(s):  
Joseph Greenberg

The Third West African Languages Congress took place in Freetown, Sierra Leone, from March 26 to April 1, 1963. This was the third of the annual meetings of those interested in West African languages sponsored by the West African Languages Survey, previous meetings having been held in Accra (1961) and Dakar (1962). The West African Languages Survey is a Ford Foundation project. Additional financial assistance from UNESCO and other sources contributed materially to the scope and success of the meeting. This meeting was larger than previous ones both in attendance and in number of papers presented and, it may be said, in regard to the scientific level of the papers presented. The official participants, seventy-two in number, came from virtually every country in West Africa, from Western European countries and from the United States. The linguistic theme of the meeting was the syntax of West African languages, and a substantial portion of the papers presented were on this topic. In addition, there was for the first time at these meetings a symposium on the teaching of English, French and African languages in Africa. The papers of this symposium will be published in the forthcoming series of monographs planned as a supplement to the new Journal of West African Languages. The other papers are to appear in the Journal of African Languages edited by Jack Berry of the School of Oriental and African Studies.


Zootaxa ◽  
2019 ◽  
Vol 4544 (3) ◽  
pp. 381 ◽  
Author(s):  
CESAR J. BENETTI ◽  
MARIANO C. MICHAT ◽  
YVES ALARIE ◽  
NEUSA HAMADA

The second- and third instar larvae of Platynectes (s. str.) decemnotatus (Aubé, 1838) are described and illustrated in detail for the first time, with special emphasis on morphometry and chaetotaxy. Larvae of P. decemnotatus can be distinguished from most other Agabinae by having secondary setae on the urogomphus and share with the other known species described in detail the presence of a ventroapical spinula on antennomere 3 and the absence of an occipital suture, natatory dorsal setae on tibia and tarsus and natatory setae on urogomphus. Platynectes decemnotatus larvae differ from larvae of Agabus Leach, 1817, Hydrotrupes Sharp, 1882 (currently in Hydrotrupini), Ilybiosoma Crotch, 1873, Ilybius Erichson, 1832 and the previously described Platynectes species in having a one-segmented urogomphus, a character previously observed only in larvae of Agabinus Crotch, 1873. The second- and third instar larvae of P. decemnotatus differ from those of P. (Agametrus) curtulus (Régimbart, 1899) in having the apical lateroventral process of antennomere 3 protruding (not protruding in P. curtulus). The third-instar larva of P. decemnotatus can also be distinguished from that of P. (Gueorguievtes) decempunctatus (Fabricius, 1775) by the absence of secondary dorsal setae on the tibia. 


1926 ◽  
Vol 6 (2) ◽  
pp. 163-165 ◽  
Author(s):  
G. McN. Rushforth

After the late Lord Curzon had bought Tattershall Castle as an empty shell, he had it roofed, the windows were glazed, and floors were inserted, so that the interior has regained something of its original use and appearance, and, in particular, it is now possible to examine in comfort the famous chimney-pieces which were rescued and replaced by Lord Curzon. As is well known, these are decorated with all the heraldry belonging to the builder of the castle, Ralph Lord Cromwell (1394–1456), including the badge of a purse to show that he was Lord Treasurer under Henry VI from 1433 to 1443. When I saw these for the first time in 1924 I noticed that on the chimney-piece of the ground-floor chamber the panels with the badge, alternating with those which contain the coats of arms, show the purse wreathed or framed by two branches or sprays of naturalistic foliage (pl. XXVI); and the same feature appears in the chimney-piece on the first floor; while on the third floor the same plant is associated with the purse in the spandrels of the fireplace arch. It is not represented on the fourth chimney-piece. The contrast between this natural leafage and the conventional carved foliage on the other parts of the chimney-pieces is very marked, and it is obviously intended to represent a real plant having a tall stem with narrow, pointed leaves. I felt sure that it must have a meaning, and this idea was confirmed when afterwards I went into the church, which was also built by Lord Cromwell, and saw, among the remains of the original painted glass, now collected in the east window, the Treasurer's purse again wreathed by similar sprays, treated rather more formally.


1992 ◽  
Vol 24 (2) ◽  
pp. 225-236 ◽  
Author(s):  
Wilfrid Prest

Conrad Russell has recently asked, not for the first time, how far the divided allegiances of members of the Long Parliament were anticipated in the parliaments of the 1620s. Many who sat as M.P.s in the third decade of the seventeenth century had died by the early 1640s, while not all those who still survived were either sufficiently vocal before 1629 or politically active after 1641 to be classifiable for the purposes of this exercise. Nevertheless, Professor Russell manages to assemble a small bloc of members whose earlier politico-religious sympathies and civil war alignments are both more or less known. This group of twenty-six men splits neatly 50:50 between Royalists and Parliamentarians. According to Russell, all that distinguished one from the other in the 1620s, and the sole effective predictor of their later allegiances, was religion. More specifically, the crucial variable turns out to be commitment to further godly reformation, strong in the case of future Parliamentarians, weak in the case of future Royalists. But for Russell's explicit rejection of any “supposed correlation between ‘Puritanism and Revolution,’” the casual reader might conclude that something resembling the Puritan Revolution was sneaking back into historio-graphical favor.


2018 ◽  
Vol 9 (2) ◽  
pp. 119-135
Author(s):  
Lucia Kurilovská ◽  
Marek Kordík

The paper deals with a  national risk assessment. The subject of  the risk assessment is money laundering and terrorism financing. This is the first time it has been conducted in the Slovak republic. The contribution shows what are the decisive criteria in evaluating the national system of anti-money laundering and terrorism financing. The  first variable that needs to be taken in account is measures examining the legal framework. The second variable is the institutional framework. The competency of personnel represents the third variable. The infrastructure creates the fourth variable in order to prevent, avoid and respond to such a threat. The other variables are strongly related to the effectiveness of the sanctions. The infrastructure belongs to the other variables. The contribution deals also with data sources and lists those that should be used as a source for further evaluation. The outcome of the NRA will be a comprehensive report.


1990 ◽  
Vol 122 (1) ◽  
pp. 77-91 ◽  
Author(s):  
Bruce P. Smith

AbstractLarvae of Arrenurus bartonensis Cook, Arrenurus birgei Marshall, Arrenurus neobirgei Cook, and Arrenurus rotundus Marshall are described for the first time. Larvae of A. rotundus can be distinguished reliably from the other three by differences in morphology. Larvae of A. bartonensis, A. birgei, and A. neobirgei are very similar, but can be separated by comparing shape and size of the excretory pore plate, and by measurements of the dorsal plate and the tarsus of the third leg.


Antiquity ◽  
1934 ◽  
Vol 8 (29) ◽  
pp. 73-80
Author(s):  
Iorwerth C. Peate

In his appendix (pages 84–5) to his Changes in the Fauna of Wales within Historic Times, Mr Colin Matheson, refers to ‘ the old Welsh text known as Y Naw Helwriaeth or The Nine Huntings [which] has been generally regarded as setting forth the hunting customs among the early Welsh ’. This text has been published in the Myvyrian Archaiology (2nd edition, pp. 872-3) and in Dr John Davies’s Dictionarium duplex (1632). Both these printed texts however differ in various details from the three known manuscript versions, and while the versions of two of the manuscripts are fairly similar, that of the third differs markedly from the other two. An edition with annotations in Welsh of the three manuscript texts was published (for the first time) by the present writer in 1933. It was thought that since the texts presented problems of interest to students of British history, a collated translation of the two texts together with a translation of the third, and differing, text would prove to be of value to those unacquainted with Welsh.


Author(s):  
Vadim V. Maiko ◽  

First time in the scholarship, this paper has analysed Byzantine imported monograms from mediaeval Sougdaia, which appeared on glazed vessels of the Elaborate Incised Ware produced in Constantinople or its environs. With the mediation of Genoese traders, a small number of this pottery was delivered to the markets of the cities in the Crimean peninsula, Sougdaia in particular. So far, many-year-long archaeological excavations discovered seven monograms of the kind, which belonged to three widely known Byzantine types. It should be mentioned that, as it has already been stated in the scholarship, the monograms with the name Michael predominate, though the other types are very few in number. Two typologically similar signs more, showing a double cross with diamond-shaped rays, are traditionally interpreted not as monograms but as ornamental elements typical of the war in question. Using the analysis of analogies and similar images, an attempt has been made to analyse and interpret this sign. All the finds under study originate from four archaeological contexts of mediaeval Sougdaia. Three of them possess a reliable dating to the third quarter of the fourteenth century, and the fourth specimen existed from the mid-fourteenth century to 1475.


Author(s):  
Simon Park

The 1590s saw what has come to be known as the ‘lyric’ poetry of many of the writers in this book printed for the first time. This chapter investigates the rush of activity in Lisbon’s print houses as the century came to a close, focusing especially on why the many individuals involved in the print trade chose to print poems that had been circulating, sometimes widely, in manuscript for quite some time. It sets out a distaste for love poetry that was frequently articulated in Inquisitorial printing licences and in the paratexts to other books printed in the period, before tracing how the terms of approval for non-devotional poetry began to shift towards the end of the sixteenth century. Three principal justifications for printing collections of poetry were presented in the period. The first involved using print to disseminate a vision of the best of the Portuguese language, simultaneously to those outside the nation, who doubt its capacity as a vehicle for ideas, and to native speakers of the language, who might learn from its most able and elegant practitioners, i.e. poets. The second reason relates more closely to the change in medium in question: editors and printers argued that print was a means of tackling the errors introduced by manuscript dissemination. The third and final justification was the desire to make a name for a poet, which ties in closely with the other justifications for print, because establishing an individual’s renown required settling their oeuvre and often involved claiming them as a national icon.


Zootaxa ◽  
2010 ◽  
Vol 2658 (1) ◽  
pp. 38 ◽  
Author(s):  
MARIANO C. MICHAT ◽  
YVES ALARIE ◽  
CHRIS H. S. WATTS

The first-instar larva of Neobidessodes Hendrich & Balke (through the hypogaeic species N. limestoneensis (Watts & Humphreys)) and the third-instar larva of Hydroglyphus Motschulsky (through H. balkei Hendrich) (Dytiscidae: Bidessini) are described and illustrated in detail for the first time, including detailed morphometric and chaetotaxic analyses of the cephalic capsule, head appendages, legs, last abdominal segment and urogomphi. A cladistic analysis including 51 characters and 32 hydroporine taxa is performed, which supports the inclusion of both genera in the tribe Bidessini based on the absence of the primary pore ABc on the last abdominal segment. The third instar of H. balkei is characterized by the absence of secondary setae on the urogomphi and anterior secondary setae on the coxa, and the presence of 8–9 secondary setae on the mesofemur. On the other hand, the first instar of N. limestoneensis bears 14 lamellae clypeales on the anteroventral margin of the nasale. This species has evolved several morphological characters that are probably associated with its hypogaeic existence, including a lightly sclerotized body, relatively longer cephalic capsule and mandibles, a strongly reduced occipital foramen, absence of stemmata, and short claws. However, primary chaetotaxy apparently has remained as a very conservative expression of the phenotype.


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