Hole diameter ratio for prediction of anatomical outcomes in stage III or IV idiopathic macular holes

Abstract Summary: In this study, we reviewed 101 eyes with stage III or IV IMHs treated by PPV combined with ILM peeling and room air tamponade, took the ratio of minimum diameter to maximum diameter (hole diameter ratio, HDR) as the predictive factor and found HDR<0.6(“A” type IMH) can be a predictive factor for a good anatomical outcome.Purpose: To identify hole diameter ratio (HDR) as the predictive factor for unclosed stage III and IV idiopathic macular holes (IMHs) by the use of preoperative optical coherence tomography (OCT).Methods: 101 eyes with stage III or IV IMH were included in this retrospective case series study. All cases were treated with vitrectomy combined with ILM peeling and room air tamponade. The MH minimum and maximum diameter, the ratio of the minimum to the maximum diameter (which defined as HDR) were performed. Results: 81 eyes (80.2%) got a Type I closure after surgery (group A). Postoperative unclosed MHs were found in 20 eyes (19.8%) (group B). The minimal diameter of IMHs (703.6±116.1um VS 597.6±120.1um, P<0.01) and HDR (0.6±0.1 VS 0.5±0.1, P=0.01) were both significantly different between two groups. The cutoff value of the receiver operating characteristic curve was 0.6. The IMH with the HDR that less than 0.6 were defined as “A” type IMH and the others were defined as “H” type IMH. The closure rate of two type IMHs were 90.2% and 65.0% respectively. It had significant differences. (P=0.002) Conclusions: HDR<0.6(“A” type IMH) can be a predictive factor for a good anatomical outcome in stage III and IV IMHs after vitrectomy combined with LM peeling and room air tamponade.

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Hole Diameter Ratio for Prediction of Anatomical Outcomes in Stage III or IV Idiopathic Macular Holes

10.21203/rs.3.rs-29158/v2 ◽

2020 ◽

Author(s):

Yue Qi ◽

Yanping Yu ◽

Qisheng You ◽

Zengyi Wang ◽

Jing Wang ◽

...

Keyword(s):

Case Series ◽

Diameter Ratio ◽

Hole Diameter ◽

Stage Iii ◽

Maximum Diameter ◽

Type I ◽

Closure Rate ◽

Macular Holes ◽

Case Series Study ◽

Idiopathic Macular Holes

Abstract Purpose: To determine whether preoperative hole diameter ratio (HDR) is a predictive factor for postoperative anatomical outome for stage III or IV idiopathic macular holes (IMHs).Methods: One-hundred and one eyes with stage III or IV IMH were included in this retrospective case series study. All cases were treated with vitrectomy combined with internal limiting membrane (ILM) peeling and room air tamponade. The macular hole (MH) minimum and maximum diameter was measured on preoperative optical coherence tomography (OCT) images. The HDR was defined as the minimum to maximum diameter ratio. Results: Eighty-one eyes (80.2%) got a Type I closure after surgery (group A). Postoperative unclosed MHs were found in 20 eyes (19.8%) (group B). The preoperative minimal diameter (703.6±116.1mm vs. 597.6±120.1mm, P<0.01) and HDR (0.6±0.1 vs. 0.5±0.1, P=0.01) were both significantly smaller in postoperative closed eyes. The closure rate of IMHs with HDR<0.6 was significantly higher than those with HDR³0.6 (90.2% vs. 65.0%P=0.002) .Conclusions: Preoperative HDR<0.6 is predictive for a good postoperative anatomical outcome in stage III or IV IMHs.

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Morphofunctional analysis of the retina in the surgical treatment of idiopathic macular holes

Modern technologies in ophtalmology ◽

10.25276/2312-4911-2021-3-48-52 ◽

2021 ◽

pp. 48-52

Author(s):

A.S. Zotov ◽

◽

A.S. Balalin ◽

S.V. Balalin ◽

S.M. Purshak ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Surgical Treatment ◽

Macular Hole ◽

Practical Importance ◽

Functional Results ◽

Hole Diameter ◽

Optical Coherence ◽

Macular Holes ◽

Idiopathic Macular Holes ◽

Morphofunctional Analysis

Purpose. To evaluate the role of microperimetry and optical coherence tomography (OCT) in the morphofunctional analysis of the retina after surgical treatment of idiopathic macular holes (IMH). Materials and methods. A retrospective study of 33 patient's treatment results (33 eyes) with IMH was carried out. All patients underwent minimally invasive with 25G or 27G vitrectomy. Best corrected visual acuity (BCVA), macular photosensitivity, fixation stability, macular neuroepithelial (NE) volume and minimal macular hole diameter were analyzed. Follow-up period: 6 months. Results. A complete closure of the macular hole was achieved in all cases post-op. The patients had reliable improvement of BCVA, retinal photosensitivity and decrease of macular NE volume. Based on a multifactor correlation analysis with the purpose to predict the results of surgical treatment, the dependence of post-op BCVA on the pre-op photosensitivity of the retina and the minimal diameter of the macular hole was revealed. Conclusions. Microperimetry and OCT are modern non-invasive research methods allowing to estimate anatomical and functional results of surgical IMH treatment. The study of retinal photosensitivity in the macula and minimal macular hole diameter pre-op allows to predict post-op BCVA, which has a practical importance. Keywords: idiopathic macular hole, vitrectomy, microperimetry, optical coherence tomography.

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Differentiated Approach to Strategies of Surgical Treatment of Idiopathic Macular Holes

The Eye ◽

10.33791/2222-4408-2021-4-12-16 ◽

2021 ◽

Vol 23 (4) ◽

pp. 12-16

Author(s):

R. Z. Shamratov ◽

L. Sh. Ramazanova ◽

O. A. Napylova

Keyword(s):

Surgical Treatment ◽

Vitreoretinal Surgery ◽

Internal Limiting Membrane ◽

Pathological Process ◽

Hole Diameter ◽

Corrected Visual Acuity ◽

Macular Holes ◽

Idiopathic Macular Holes ◽

Anatomical Outcome ◽

Clinical Cases

Background. 25G or 27G three-port vitrectomy, followed by staining and removal of the internal limiting membrane with vitreous cavity air or gas tamponade, is one of the main modern vitreoretinal surgery principles for primary macular holes. However, not all patients manage to obtain a functional outcome when the anatomical outcome is achieved. Purpose. To present clinical cases of surgical treatment of idiopathic macular holes (IMH) exhibiting a differentiated approach.Matherials and methods. This article analyzes clinical cases of four patients with primary idiopathic macular holes, differing in terms of development, hole diameter and the presence of comorbidities. Results. The results of surgical treatment were evaluated 14 days and 1 month after surgery. In all clinical cases, surgical treatment resulted in a positive anatomical outcome by blocking a retinal defect. Best corrected visual acuity increased, on average, from 0.08 ± 0.05 to 0.4 ± 0.05.Conclusion. The analysis of the presented clinical cases clearly demonstrates the need for a timely and differentiated approach to the treatment of patients with IMH, that considers etiology of the pathological process, period of its existence as well as concomitant and general somatic pathologies.

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The use of internal limiting membrane maculorrhexis in treatment of idiopathic macular holes

Korean Journal of Ophthalmology ◽

10.3341/kjo.1998.12.2.92 ◽

1998 ◽

Vol 12 (2) ◽

pp. 92 ◽

Cited By ~ 20

Author(s):

D W Park ◽

J H Lee ◽

W K Min

Keyword(s):

Internal Limiting Membrane ◽

Macular Holes ◽

Idiopathic Macular Holes

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Effects of Hole Pitch to Diameter Ratio P/D of Impingement and Film Hole on Laminated Cooling Effectiveness

Volume 5A: Heat Transfer ◽

10.1115/gt2017-64566 ◽

2017 ◽

Cited By ~ 2

Author(s):

Weilun Zhou ◽

Qinghua Deng ◽

Wei He ◽

Zhenping Feng

Keyword(s):

Mass Flux ◽

Pressure Loss ◽

Pressure Ratio ◽

Diameter Ratio ◽

Hole Diameter ◽

Heat Transfer Analysis ◽

Internal Cooling ◽

Cooling Effectiveness ◽

System Pressure ◽

The Difference

The laminated cooling, also known as impingement-effusion cooling, is believed to be a promising gas turbine blade cooling technique. In this paper, conjugate heat transfer analysis was employed to investigate the overall cooling effectiveness and total pressure loss of the laminated cooling configuration. The pitch to film hole diameter ratio P/Df of 3, 4, 5, 6, combined with pitch to impingement hole diameter ratio P/Di of 4, 6, 8, 10, are studied at the coolant mass flux G of 0.5, 1.0, 1.5, 2.0 kg/(sm2bar) respectively. The results show that overall cooling effectiveness of laminated cooling configuration increases with the decreasing of P/Df and the increasing of the coolant mass flux in general. However P/Df smaller than 3 may leads to a serious blocking in first few film holes at low coolant mass flux. The large P/Di that makes the Mach number of impingement flow greater than 0.16 may cause unacceptable pressure loss. The increment of overall cooling effectiveness depends on the difference between the deterioration of external cooling and the enhancement of internal cooling. Pressure loss increases exponentially with P/Di and G, and it increases more slowly with P/Df that compared to P/Di and G. The mixing loss takes up the most pressure loss at low coolant mass flux. With the increasing of the whole pressure loss, the proportion of throttling loss and laminated loss becomes larger and finally takes up the most of the whole pressure loss. When the sum of throttling loss and laminated loss is greater than mixing loss, the increment of system pressure ratio is unreasonable that compared to the increment of overall cooling effectiveness.

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Optical Coherence Tomography Findings in Idiopathic Macular Holes

Journal of Ophthalmology ◽

10.1155/2011/928205 ◽

2011 ◽

Vol 2011 ◽

pp. 1-4 ◽

Cited By ~ 5

Author(s):

Lynn L. Huang ◽

David H. Levinson ◽

Jonathan P. Levine ◽

Umar Mian ◽

Irena Tsui

Keyword(s):

Optical Coherence Tomography ◽

Macular Hole ◽

Clinical Assessment ◽

Chart Review ◽

Subretinal Fluid ◽

Optical Coherence ◽

Cross Sectional ◽

Macular Holes ◽

Idiopathic Macular Holes ◽

Intraretinal Cysts

Purpose. To describe the characteristics of idiopathic macular holes (MH) on optical coherence tomography (OCT) and correlate OCT with clinical assessment.Design. Cross-sectional chart review and OCT assessment.Participants. Sixty-seven eyes with a clinically diagnosed idiopathic MH with available OCT data.Methods. A retrospective chart review and OCT assessment.Results. Based on OCT grading, 40 eyes had a full-thickness macular hole (FTMH) and 21 eyes had a lamellar macular hole (LMH). Clinical exam and OCT assessment agreed in 53 (87%) eyes when assessing the extent of MH. Six eyes (14.6%) in the FTMH group, and 3 eyes in the LMH group (14.3%) had persistent vitreomacular traction. Thirty-seven eyes (92.5%) in the FTMH group and 11 eyes (52.4%) in the LMH group had associated intraretinal cysts. Two eyes (5.0%) in the FTMH group and zero eyes in the LMH group had subretinal fluid. Intraretinal cysts were found to be more frequently associated with FTMH than with LMH (P<0.001).Conclusion. This paper described OCT findings in a group of patients with clinically diagnosed MH. A high level of correlation between clinical assessment and OCT findings of LMH and FTMH was observed, and intraretinal cysts were often present in FTMH.

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