scholarly journals Influence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO)

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Christian Apfelbacher ◽  
◽  
Susanne Brandstetter ◽  
Sebastian Blecha ◽  
Frank Dodoo-Schittko ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Acute Respiratory Distress Syndrome ◽  
Cohort Study ◽  
Intensive Care ◽  
Respiratory Distress Syndrome ◽  
Return To Work ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Patient Cohort

scholarly journals Clinical characteristics and post-intensive care outcomes of COVID-19 pneumonia.

2020 ◽  
Author(s):  
Neil MD C ◽  
Samuel M Lakey ◽  
Sean M McMahon ◽  
Megan K Downey ◽  
Megan S Duncan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Acute Respiratory Distress Syndrome ◽  
Intensive Care ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Case Series ◽  
Evidence Based

Abstract Background: COVID-19 can result in a severe viral pneumonia, with high reported mortality rates in patients requiring mechanical ventilation. There is controversy as to whether established therapeutic approaches to acute respiratory distress syndrome are optimal in this condition, and numerous novel therapies have been used, often outside the context of randomised trials. In addition, longer term quality of life outcomes associated with COVID-19 are as yet unknown. The aim of this case series is to describe demographic, physiological and outcome data of patients with COVID-19 admitted to our intensive care units who were treated according to evidence-based guidelines for acute respiratory distress syndrome.Methods: We retrospectively reviewed the records of all patients admitted to intensive care units in our institution with COVID-19 between March and June, 2020. Physiological and laboratory data were recorded at baseline and daily until intensive care discharge or death. Quality of life was assessed at a virtual post-intensive care follow-up clinic around 10 weeks after ICU discharge.Results: 45 patients with COVID-19 were included, 37 (82.2%) of whom were male, with a mean age of 55 years. 42 (93.3%) of this cohort met criteria for acute respiratory distress syndrome at time of admission. Clinical management was consistent with evidence based institutional guidelines introduced for acute respiratory distress syndrome. Median length of intensive care stay was 14 days. The intensive care mortality rate was 8.9%. Functional and psychological morbidity post intensive care was significant: 45.2% of respondents had at least moderate impairment of mobility and 35.5% described at least moderate symptoms of anxiety or depression at the time of follow up.Conclusions : This case series demonstrates low mortality in a cohort of patients treated according to an established evidence-based approach for acute respiratory distress syndrome. However, COVID-19 survivors have a marked functional and psychological morbidity impacting quality of life following ICU admission. The therapeutic goal in the future will be to achieve similar survival outcomes while minimizing the significant morbidity associated with COVID-19 related critical care admission.

scholarly journals Long-Term Pulmonary Function and Quality of Life in Children After Acute Respiratory Distress Syndrome

2017 ◽  
Vol 18 (1) ◽  
pp. e48-e55 ◽  
Author(s):  
Shan L. Ward ◽  
Autumn Turpin ◽  
Aaron C. Spicer ◽  
Marsha J. Treadwell ◽  
Gwynne D. Church ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Acute Respiratory Distress Syndrome ◽  
Pulmonary Function ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome

Long-term pulmonary function and quality of life in adults after extracorporeal membrane oxygenation for respiratory failure

Perfusion ◽  
2019 ◽  
Vol 34 (1_suppl) ◽  
pp. 49-57 ◽  
Author(s):  
Viktor von Bahr ◽  
Håkan Kalzén ◽  
Björn Frenckner ◽  
Jan Hultman ◽  
K Gunilla Frisén ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Acute Respiratory Distress Syndrome ◽  
Extracorporeal Membrane Oxygenation ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Diffusion Capacity ◽  
Membrane Oxygenation

Background: There is a significant long-term burden on survivors after acute respiratory distress syndrome, even 5 years after discharge. This is not well investigated in patients treated with extracorporeal membrane oxygenation. The objective of this study was to describe very-long-term (⩾3 years) disability in lung function and morphology, quality of life, mood disorders, walking capacity, and return to work status in extracorporeal membrane oxygenation survivors. Methods: Single-center retrospective cohort study on long-term survivors treated with extracorporeal membrane oxygenation for respiratory failure between 1995 and 2010 at a tertiary referral center in Sweden. Eligible patients were approached, and those who consented were interviewed and investigated during a day at the hospital. Results: A total of 38 patients were investigated with a median follow-up time of 9.0 years. Quality of life was reduced in several Short form 36 (SF-36) subscales and all domains of the St George’s Respiratory Questionnaire, similar to previous studies in conventionally managed acute respiratory distress syndrome survivors. A reduced diffusion capacity of carbon monoxide was seen in 47% of patients, and some degree of residual lung parenchymal pathology was seen in 82%. Parenchymal pathology correlated with reductions in quality of life and diffusion capacity. Symptoms of anxiety and depression were seen in 22% and 14%, respectively. Conclusion: A significant long-term burden remains even 3–17 years after extracorporeal membrane oxygenation treatment, similar to conventionally managed acute respiratory distress syndrome survivors. Future prospective studies are needed to elucidate risk factors for these sequelae.

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