scholarly journals Severe infection including disseminated herpes zoster triggered by subclinical Cushing’s disease: a case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yuki Yamauchi ◽  
Hiraku Kameda ◽  
Kazuno Omori ◽  
Michio Tani ◽  
Kyu Yong Cho ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Cushing’S Disease ◽  
Cardiopulmonary Arrest ◽  
Severe Infection ◽  
Japanese Woman ◽  
The Body ◽  
Cushing's Disease ◽  
Old Japanese ◽  
Subclinical Cushing’S Disease ◽  
Physical Features

Abstract Background Subclinical Cushing’s disease (SCD) is defined by corticotroph adenoma-induced mild hypercortisolism without typical physical features of Cushing’s disease. Infection is an important complication associated with mortality in Cushing’s disease, while no reports on infection in SCD are available. To make clinicians aware of the risk of infection in SCD, we report a case of SCD with disseminated herpes zoster (DHZ) with the mortal outcome. Case presentation An 83-year-old Japanese woman was diagnosed with SCD, treated with cabergoline in the outpatient. She was hospitalized for acute pyelonephritis, and her fever gradually resolved with antibiotics. However, herpes zoster appeared on her chest, and the eruptions rapidly spread over the body. She suddenly went into cardiopulmonary arrest and died. Autopsy demonstrated adrenocorticotropic hormone-positive pituitary adenoma, renal abscess, and DHZ. Conclusions As immunosuppression caused by SCD may be one of the triggers of severe infection, the patients with SCD should be assessed not only for the metabolic but also for the immunodeficient status.

scholarly journals Neuroleptic malignant syndrome as part of an akinetic crisis associated with sepsis in a patient with Lewy body disease

2019 ◽  
Vol 12 (2) ◽  
pp. bcr-2018-227216 ◽  
Author(s):  
Saki Manabe ◽  
Hidetaka Yanagi ◽  
Hideki Ozawa ◽  
Atsushi Takagi
Keyword(s):  
Neuroleptic Malignant Syndrome ◽  
Lewy Body ◽  
Cardiopulmonary Arrest ◽  
Lewy Body Disease ◽  
Kidney Injury ◽  
Spontaneous Circulation ◽  
Japanese Woman ◽  
Old Japanese ◽  
History Of ◽  
Tentative Diagnosis

A 65-year-old Japanese woman with Parkinson’s disease, later diagnosed with Lewy body disease, presented with a 2-day history of systemic tremors. She also had fever without rigidity or creatine kinase (CK) elevation. She was diagnosed with sepsis caused by pyelonephritis with acute kidney injury and parkinsonism exacerbation. Although antibiotic and fluid therapy improved her pyuria and renal function, her fever and tremors persisted. On the fourth day, her symptoms worsened and resulted in cardiopulmonary arrest; however, quick resuscitation allowed the return of spontaneous circulation. Simultaneously, hyperthermia, altered consciousness, extrapyramidal symptoms, dysautonomia and CK elevation were noted. Thus, dantrolene administration was initiated with a tentative diagnosis of neuroleptic malignant syndrome (NMS). This caused her fever to subside, and her symptoms gradually improved. It was difficult to distinguish between parkinsonism exacerbation associated with sepsis and NMS. Physicians should consider NMS early on, even if the patient does not fulfil the diagnostic criteria.

Case report of pituitary adenoma with subclinical Cushing's disease

2019 ◽  
Author(s):  
Dimitra Tampouratzi ◽  
Styliani Kalaitzidou ◽  
Georgios Papadakis ◽  
Chrysi Karavasili ◽  
Michalis Kotis ◽  
...  
Keyword(s):  
Case Report ◽  
Pituitary Adenoma ◽  
Cushing’S Disease ◽  
Cushing's Disease ◽  
Subclinical Cushing’S Disease

scholarly journals A Case of Acromegaly Associated with Subclinical Cushing's Disease

2006 ◽  
Vol 53 (5) ◽  
pp. 679-685 ◽  
Author(s):  
Kyoichiro TSUCHIYA ◽  
Kazuki OHTA ◽  
Takanobu YOSHIMOTO ◽  
Masaru DOI ◽  
Hajime IZUMIYAMA ◽  
...  
Keyword(s):  
Cushing’S Disease ◽  
Cushing's Disease ◽  
Subclinical Cushing’S Disease

Acromegaly and subclinical Cushing's disease: a rare case of a pituitary macroadenoma secreting both GH and ACTH

2018 ◽  
Author(s):  
Teodora Teusan ◽  
Mihaela Ciobotar ◽  
Maria-Christina Ungureanu ◽  
Cristina Preda ◽  
Alexandru Florescu ◽  
...  
Keyword(s):  
Cushing’S Disease ◽  
Rare Case ◽  
Cushing's Disease ◽  
Pituitary Macroadenoma ◽  
Subclinical Cushing’S Disease

scholarly journals Adult acetonemic vomiting complicated with low body weight in a subject with Mycobacterium avium complex pulmonary disease: A case report

2021 ◽  
Author(s):  
Hitomi Tanaka ◽  
Takatoshi Anno ◽  
Haruka Takenouchi ◽  
Fumiko Kawasaki ◽  
Katsumi Kurokawa ◽  
...  
Keyword(s):  
Body Weight ◽  
Pulmonary Disease ◽  
Ketone Bodies ◽  
Diet Therapy ◽  
Japanese Woman ◽  
The Body ◽  
Nausea And Vomiting ◽  
Pulmonary Diseases ◽  
Main Complaint ◽  
Old Japanese

Abstract BackgroundPulmonary diseases often bring about a significant health issue and nutritional disorders. Weight loss and malnutrition are related to the severity of obstructive disorders. Therefore, such patients easily fall into lack of nutritional energy. Acetonemic vomiting is caused by acetonemic syndrome and recently it has been considered that acetonemic vomiting can occur at any age from infancy to adulthood. It is considered that acetonemic vomiting is likely brought about in subjects with low body weight, because stored carbohydrates in the body are reduced and fats are mainly utilized. As the results, large amounts of acetone are produced, which causes nausea and vomiting together with hypoglycemia.Case presentationA 79-year-old Japanese woman was brought to an emergency room with symptoms of nausea and vomiting. She was diagnosed as MAC pulmonary disease at the age of 52. Her height, body weight and body mass index (BMI) were 155.4 cm, 33.5 kg and 13.9 kg/m2, respectively. she had slight hypoglycemia and urinary ketone bodies. Surprisingly, she had been hospitalized four times within one year and her main complaint in every hospitalization were nausea and vomiting. Moreover, at every hospitalization, she had repeated slight hypoglycemia and urinary ketone bodies. Based on such findings, we finally diagnosed her as acetonemic vomiting complicated with low body weight. We started the education and diet therapy for her and after then she has not been hospitalized for one year.ConclusionsWe should bear in mind that the subjects with pulmonary diseases are often complicated with low body weight and thereby they could have acetonemic vomiting with slight hypoglycemia and ketosis. It is very important that such pulmonary diseases patients with low body weight and repeated nausea and/or vomiting get appropriate education and diet therapy, because their repeated symptoms can be mitigated by such therapy.

Sign in / Sign up

Export Citation Format

Share Document