scholarly journals Serum protein gamma-glutamyl hydrolase, Ig gamma-3 chain C region, and haptoglobin are associated with the syndromes of pulmonary tuberculosis in traditional Chinese medicine

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Ting-Ting Jiang ◽  
Chong Wang ◽  
Li-Liang Wei ◽  
Xiao-Mei Yu ◽  
Li-Ying Shi ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Pulmonary Tuberculosis ◽  
Serum Protein ◽  
Gamma Glutamyl

scholarly journals Traditional Chinese medicine combined with western medicine for the treatment of secondary pulmonary tuberculosis

Medicine ◽  
2020 ◽  
Vol 99 (16) ◽  
pp. e19567
Author(s):  
Xiangwen Li ◽  
Xinghui Li ◽  
Qiling Liu ◽  
Na Sun ◽  
Bei Zhang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Pulmonary Tuberculosis ◽  
Western Medicine

scholarly journals Antidiabetic Properties and Possible Mechanism of the Traditional Chinese Medicine Yi Qi Yang Yin Recipe in Db/db Mice

2021 ◽  
Author(s):  
Hongmei Lin ◽  
Ziying Xu ◽  
Baosheng Zhao ◽  
Jingxuan Zhang ◽  
Zilan Zhang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Serum Protein ◽  
Water Consumption ◽  
Liver Tissue ◽  
Fasting Blood Glucose ◽  
Tissue Morphology

Abstract Background Yi Qi Yang Yin Recipe (YQYY) is a well-known clinical prescription used in Traditional Chinese Medicine (TCM) that ameliorates type 2 diabetes. The aim of the present study was to comprehensively evaluate the efficacy of YQYY granules and explore their mechanism of action. Methods db/db mice were studied as an animal model of type 2 diabetes. After administered with YQYY for eight weeks, food and water consumption, levels of fasting blood glucose, glycosylated serum protein, and liver and pancreas tissue morphology were investigated. In addition, RT-PCR and Westernblot analysis were used to determine the expression of genes and proteins related to glycogen synthesis and gluconeogenesis pathways in the liver. Results YQYY resulted in significantly reduced food and water consumption, and lower fasting blood glucose and glycated serum protein levels. Furthermore, the proliferation of α-cells in db/db mouse pancreatic tissue decreased and liver tissue morphology was significantly ameliorated. YQYY upregulated the expression of phosphorylated GSK-3β and GS proteins in db/db mouse liver tissue, and promoted the synthesis of liver glycogen. Additionally, AMPK was activated, PEPCK and G6Pase gene expression levels decreased, and consequently, gluconeogenesis in the liver was inhibited. Therefore, YQYY improves diabetic phenotyp, suggesting that YQYY could be a prospective agent for preventing and treatment diabetes .

scholarly journals Screening of Serum Protein Markers for Avascular Osteonecrosis of Femoral Head Differentially Expressed after Treatment with Yuanshi Shengmai Chenggu Tablets

2018 ◽  
Vol 2018 ◽  
pp. 1-21 ◽  
Author(s):  
Peng Deng ◽  
Jianchun Zeng ◽  
Jie Li ◽  
Wenjun Feng ◽  
Jinlun Chen ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Femoral Head ◽  
Traditional Chinese Medicine ◽  
Avascular Necrosis ◽  
Serum Protein ◽  
Multiple Reaction Monitoring ◽  
Femoral Head Necrosis ◽  
High Morbidity ◽  
Avascular Osteonecrosis ◽  
Protein Marker

Avascular necrosis of the femoral head (ANFH) is an a frequently occurring orthopaedic disease with high morbidity. Traditional Chinese Medicine (TCM) Yuanshi Shengmai Chenggu Tablet is a valid prescription for treating steroid-induced femoral head necrosis. However, there are rare investigations about the serum protein marker expression after the acting of drugs on hormone and TCM. In the present study, we aimed to systematically discover and validate the serum biomarkers expression difference in patients with steroid-induced avascular necrosis of femoral head (SANFH) after taking Yuanshi Shengmai Chenggu Tablets (SANFH-TCM), so as to reveal the action mechanism of TCM from the molecular level by using isobaric tags for relative and absolute quantification (iTRAQ) with multiple reaction monitoring quantification. Significant differences in fibrinogen alpha, fibrinogen beta, fibrinogen gamma, fibronectin, C-reactive protein, apolipoprotein A, apolipoprotein D, and apolipoprotein E were found among SANFH, SANFH-TCM, and healthy controls. Therefore, our study proposes potential biomarkers for SANFH diagnosis and for the prognosis of femoral head necrosis after Traditional Chinese Medicine treatment.

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