scholarly journals Water-soluble polyphenol-rich clove extract lowers pre- and post-prandial blood glucose levels in healthy and prediabetic volunteers: an open label pilot study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ratheesh Mohan ◽  
Svenia Jose ◽  
Johannah Mulakkal ◽  
Darla Karpinsky-Semper ◽  
Andrew G. Swick ◽  
...  
2004 ◽  
Vol 28 (8) ◽  
pp. 292-294 ◽  
Author(s):  
Helen Smith ◽  
Tom White

Aims and MethodThis study aimed to investigate the potential benefits of a low glycaemic index diet in patients with schizophrenia taking clozapine. Seven patients consented to participate in a 5-week pilot study. Measurements were taken of body weight, random blood glucose and cholesterol levels.ResultsThe mean weight loss per patient was 2.9 kg in 4 weeks. Random blood glucose levels reduced from a mean of 5.3 mmol/l at the beginning of the study to 4.7 mmol/l at the end.Clinical ImplicationsA low glycaemic index diet may possibly reduce the substantial cardiovascular risk in patients receiving antipsychotic medication.


2017 ◽  
Vol 27 (4) ◽  
pp. 27604
Author(s):  
Maria das Graças Bastos Licurci ◽  
Alessandra De Almeida Fagundes ◽  
Emilia Angela Lo Schiavo Arisawa

***Whole body vibration and blood glucose levels in elderly people: a pilot study***AIMS: To evaluate the effect of whole-body vibration therapy on blood glucose levels of elderly people using a vibratory platform.METHODS: The study included volunteers of both genders, aged between 60 and 75 years, without gait disorders or motor disabilities. Individuals with systemic disease, obesity, conflicting treatments, tobacco users, and those who could not understand the maneuvers were excluded. The study consisted of a single session of whole-body vibration. Heart rate, respiratory rate, arterial blood pressure, and blood glucose were obtained for each participant at baseline, immediately before the procedure. Volunteers were then placed in the standing position on the ground of an oscillating platform and treated for 10 min with a frequency of vibration set at 20 Hz (displacement  ±6 mm; orbital vibration). Immediately after the whole-body vibration session, all data were collected again. Comparisons were made between baseline and post-treatment data. Normality was tested by Kolmogorov-Smirnov test. Data were analyzed using paired Student’s t-test or Wilcoxon test as appropriate. The level of significance was set at p<0.05.RESULTS: Eleven participants (seven men, four women) participated of the study. The mean age was 64.18±4.37 years. The results showed a significant decrease in the glycemic indexes (p=0.016) and an increase in the respiratory rate (p=0.047) after the whole-body vibration session.CONCLUSIONS: Healthy elderly subjected for 10 minutes to whole-body vibration set at 20 Hz presented reduction of blood glucose levels and increasing of respiratory rate.


2017 ◽  
Vol 27 (4) ◽  
pp. 27604 ◽  
Author(s):  
Maria das Graças Bastos Licurci ◽  
Alessandra De Almeida Fagundes ◽  
Emilia Angela Lo Schiavo Arisawa

***Whole body vibration and blood glucose levels in elderly people: a pilot study***AIMS: To evaluate the effect of whole-body vibration therapy on blood glucose levels of elderly people using a vibratory platform.METHODS: The study included volunteers of both genders, aged between 60 and 75 years, without gait disorders or motor disabilities. Individuals with systemic disease, obesity, conflicting treatments, tobacco users, and those who could not understand the maneuvers were excluded. The study consisted of a single session of whole-body vibration. Heart rate, respiratory rate, arterial blood pressure, and blood glucose were obtained for each participant at baseline, immediately before the procedure. Volunteers were then placed in the standing position on the ground of an oscillating platform and treated for 10 min with a frequency of vibration set at 20 Hz (displacement  ±6 mm; orbital vibration). Immediately after the whole-body vibration session, all data were collected again. Comparisons were made between baseline and post-treatment data. Normality was tested by Kolmogorov-Smirnov test. Data were analyzed using paired Student’s t-test or Wilcoxon test as appropriate. The level of significance was set at p<0.05.RESULTS: Eleven participants (seven men, four women) participated of the study. The mean age was 64.18±4.37 years. The results showed a significant decrease in the glycemic indexes (p=0.016) and an increase in the respiratory rate (p=0.047) after the whole-body vibration session.CONCLUSIONS: Healthy elderly subjected for 10 minutes to whole-body vibration set at 20 Hz presented reduction of blood glucose levels and increasing of respiratory rate.


2018 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Sentot Joko Raharjo

White bentul tuber is one of tuber plant species which have bioactive compound of Water Soluble Polysaccharide (WSP) and potentially healthy nutrition in the therapy of metabolic syndrome disease. The purpose of this research is to prove the ability of WSP isolate to reduce blood glucose level in white mice.  Research method include the yield of WSP isolates white bentul tuber using enzymatic method, WSP identification using HPLC with Aminex HPX-87C BIORAD5 columns, and antidiabetic activity test using white mices. Test activity was performed in six treatment groups (Normal, Induction STZ 20 mg/ kgBW, Induction STZ 20 mg / kgBW + metformin 195mg / KgBW, three treatment with STZ induction 20 mg/ kgBW and WSP isolate with concentration 200, 400, and 600mg / kgBW). Determination of blood glucose levels using glucometer and supported by observation of histologic improvement of beta pancreatic cells in white mice that have necrosis. The result research are WSP yield of 4.81% and WSP level of 94.45%. Results of blood glucose levels of mice induced STZ 20mg/kgBW decreased optimal blood glucose with a dose of WSP 400mg/kgBW in the first week and histologic improvement of beta pancreatic cells that experienced the most optimal necrosis at WSP dose of 200 mg/kgBW. The conclusion of this research is the provision WSP isolate of white bentul tubers at doses of 200, 400, 600 mg/kgBW can decrease the blood glucose level induced STZ 20mg/kg BW and histological improvement in pancreatic beta cells at the most optimal dose of 200 mg / kgKeywords: White bentul tuber, water soluble polysaccharides, diabetes mellitus, beta pancratic cells   


2021 ◽  
Vol 6 (4) ◽  
Author(s):  
Amanda R. Bonikowske ◽  
Katie C. Carpenter ◽  
Steven D. Stovitz ◽  
Dipankar Bandyopadhyay ◽  
Mark A. Pereira ◽  
...  

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