scholarly journals A hybrid neural network model for predicting kidney disease in hypertension patients based on electronic health records

Author(s):  
Yafeng Ren ◽  
Hao Fei ◽  
Xiaohui Liang ◽  
Donghong Ji ◽  
Ming Cheng
JMIR Cancer ◽  
10.2196/19812 ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. e19812
Author(s):  
Chia-Wei Liang ◽  
Hsuan-Chia Yang ◽  
Md Mohaimenul Islam ◽  
Phung Anh Alex Nguyen ◽  
Yi-Ting Feng ◽  
...  

Background Hepatocellular carcinoma (HCC), usually known as hepatoma, is the third leading cause of cancer mortality globally. Early detection of HCC helps in its treatment and increases survival rates. Objective The aim of this study is to develop a deep learning model, using the trend and severity of each medical event from the electronic health record to accurately predict the patients who will be diagnosed with HCC in 1 year. Methods Patients with HCC were screened out from the National Health Insurance Research Database of Taiwan between 1999 and 2013. To be included, the patients with HCC had to register as patients with cancer in the catastrophic illness file and had to be diagnosed as a patient with HCC in an inpatient admission. The control cases (non-HCC patients) were randomly sampled from the same database. We used age, gender, diagnosis code, drug code, and time information as the input variables of a convolution neural network model to predict those patients with HCC. We also inspected the highly weighted variables in the model and compared them to their odds ratio at HCC to understand how the predictive model works Results We included 47,945 individuals, 9553 of whom were patients with HCC. The area under the receiver operating curve (AUROC) of the model for predicting HCC risk 1 year in advance was 0.94 (95% CI 0.937-0.943), with a sensitivity of 0.869 and a specificity 0.865. The AUROC for predicting HCC patients 7 days, 6 months, 1 year, 2 years, and 3 years early were 0.96, 0.94, 0.94, 0.91, and 0.91, respectively. Conclusions The findings of this study show that the convolutional neural network model has immense potential to predict the risk of HCC 1 year in advance with minimal features available in the electronic health records.


2020 ◽  
Author(s):  
Chia-Wei Liang ◽  
Hsuan-Chia Yang ◽  
Md Mohaimenul Islam ◽  
Phung Anh Alex Nguyen ◽  
Yi-Ting Feng ◽  
...  

BACKGROUND Hepatocellular carcinoma (HCC), usually known as hepatoma, is the third leading cause of cancer mortality globally. Early detection of HCC helps in its treatment and increases survival rates. OBJECTIVE The aim of this study is to develop a deep learning model, using the trend and severity of each medical event from the electronic health record to accurately predict the patients who will be diagnosed with HCC in 1 year. METHODS Patients with HCC were screened out from the National Health Insurance Research Database of Taiwan between 1999 and 2013. To be included, the patients with HCC had to register as patients with cancer in the catastrophic illness file and had to be diagnosed as a patient with HCC in an inpatient admission. The control cases (non-HCC patients) were randomly sampled from the same database. We used age, gender, diagnosis code, drug code, and time information as the input variables of a convolution neural network model to predict those patients with HCC. We also inspected the highly weighted variables in the model and compared them to their odds ratio at HCC to understand how the predictive model works RESULTS We included 47,945 individuals, 9553 of whom were patients with HCC. The area under the receiver operating curve (AUROC) of the model for predicting HCC risk 1 year in advance was 0.94 (95% CI 0.937-0.943), with a sensitivity of 0.869 and a specificity 0.865. The AUROC for predicting HCC patients 7 days, 6 months, 1 year, 2 years, and 3 years early were 0.96, 0.94, 0.94, 0.91, and 0.91, respectively. CONCLUSIONS The findings of this study show that the convolutional neural network model has immense potential to predict the risk of HCC 1 year in advance with minimal features available in the electronic health records.


Author(s):  
Laxmi Kumari Pathak ◽  
Pooja Jha

Chronic kidney disease (CKD) is a disorder in which the kidneys are weakened and become unable to filter blood. It lowers the human ability to remain healthy. The field of biosciences has progressed and produced vast volumes of knowledge from electronic health records. Heart disorders, anemia, bone diseases, elevated potassium, and calcium are the very prevalent complications that arise from kidney failure. Early identification of CKD can improve the quality of life greatly. To achieve this, various machine learning techniques have been introduced so far that use the data in electronic health record (EHR) to predict CKD. This chapter studies various machine learning algorithms like support vector machine, random forest, probabilistic neural network, Apriori, ZeroR, OneR, naive Bayes, J48, IBk (k-nearest neighbor), ensemble method, etc. and compares their accuracy. The study aims in finding the best-suited technique from different methods of machine learning for the early detection of CKD by which medical professionals can interpret model predictions easily.


Energies ◽  
2020 ◽  
Vol 13 (24) ◽  
pp. 6512
Author(s):  
Mario Tovar ◽  
Miguel Robles ◽  
Felipe Rashid

Due to the intermittent nature of solar energy, accurate photovoltaic power predictions are very important for energy integration into existing energy systems. The evolution of deep learning has also opened the possibility to apply neural network models to predict time series, achieving excellent results. In this paper, a five layer CNN-LSTM model is proposed for photovoltaic power predictions using real data from a location in Temixco, Morelos in Mexico. In the proposed hybrid model, the convolutional layer acts like a filter, extracting local features of the data; then the temporal features are extracted by the long short-term memory network. Finally, the performance of the hybrid model with five layers is compared with a single model (a single LSTM), a CNN-LSTM hybrid model with two layers and two well known popular benchmarks. The results also shows that the hybrid neural network model has better prediction effect than the two layer hybrid model, the single prediction model, the Lasso regression or the Ridge regression.


Water ◽  
2018 ◽  
Vol 10 (5) ◽  
pp. 632 ◽  
Author(s):  
You-Da Jhong ◽  
Chang-Shian Chen ◽  
Hsin-Ping Lin ◽  
Shien-Tsung Chen

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