Application of Machine Learning in Chronic Kidney Disease Risk Prediction Using Electronic Health Records (EHR)

2021 ◽  
pp. 213-233
Author(s):  
Laxmi Kumari Pathak ◽  
Pooja Jha
Keyword(s):  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Electronic Health Records ◽  
Bone Diseases ◽  
Machine Learning Algorithms ◽  
Health Records ◽  
Chronic Kidney Disease Risk ◽  
Electronic Health ◽  
Heart Disorders

Chronic kidney disease (CKD) is a disorder in which the kidneys are weakened and become unable to filter blood. It lowers the human ability to remain healthy. The field of biosciences has progressed and produced vast volumes of knowledge from electronic health records. Heart disorders, anemia, bone diseases, elevated potassium, and calcium are the very prevalent complications that arise from kidney failure. Early identification of CKD can improve the quality of life greatly. To achieve this, various machine learning techniques have been introduced so far that use the data in electronic health record (EHR) to predict CKD. This chapter studies various machine learning algorithms like support vector machine, random forest, probabilistic neural network, Apriori, ZeroR, OneR, naive Bayes, J48, IBk (k-nearest neighbor), ensemble method, etc. and compares their accuracy. The study aims in finding the best-suited technique from different methods of machine learning for the early detection of CKD by which medical professionals can interpret model predictions easily.

scholarly journals Chronic Kidney Disease Prediction using Machine Learning Models

2019 ◽  
Vol 9 (1) ◽  
pp. 6364-6367
Keyword(s):  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Kidney Failure ◽  
Bone Diseases ◽  
Machine Learning Algorithms ◽  
Knowledge Generation ◽  
Good Prediction ◽  
Worst Case ◽  
Wide Range

The field of biosciences have advanced to a larger extent and have generated large amounts of information from Electronic Health Records. This have given rise to the acute need of knowledge generation from this enormous amount of data. Data mining methods and machine learning play a major role in this aspect of biosciences. Chronic Kidney Disease(CKD) is a condition in which the kidneys are damaged and cannot filter blood as they always do. A family history of kidney diseases or failure, high blood pressure, type 2 diabetes may lead to CKD. This is a lasting damage to the kidney and chances of getting worser by time is high. The very common complications that results due to a kidney failure are heart diseases, anemia, bone diseases, high potasium and calcium. The worst case situation leads to complete kidney failure and necessitates kidney transplant to live. An early detection of CKD can improve the quality of life to a greater extent. This calls for good prediction algorithm to predict CKD at an earlier stage . Literature shows a wide range of machine learning algorithms employed for the prediction of CKD. This paper uses data preprocessing,data transformation and various classifiers to predict CKD and also proposes best Prediction framework for CKD. The results of the framework show promising results of better prediction at an early stage of CKD

scholarly journals Extracting Deep Phenotypes for Chronic Kidney Disease using Electronic Health Records

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Duc Thanh Anh Luong ◽  
Dinh Tran ◽  
Wilson D Pace ◽  
Miriam Dickinson ◽  
Joseph Vassalotti ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Electronic Health Records ◽  
Health Records ◽  
Electronic Health

scholarly journals Extracting Deep Phenotypes for Chronic Kidney Disease Using Electronic Health Records

2017 ◽  
Vol 5 (1) ◽  
pp. 9 ◽  
Author(s):  
Duc Thanh Anh Luong ◽  
Dinh Tran ◽  
Wilson D. Pace ◽  
Miriam Dickinson ◽  
Joseph Vassalotti ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Electronic Health Records ◽  
Health Records ◽  
Electronic Health

scholarly journals Dense phenotyping from electronic health records enables machine-learning-based prediction of preterm birth

2020 ◽  
Author(s):  
Abin Abraham ◽  
Brian L Le ◽  
Idit Kosti ◽  
Peter Straub ◽  
Digna R Velez Edwards ◽  
...  
Keyword(s):  
Machine Learning ◽  
Risk Factors ◽  
Preterm Birth ◽  
Electronic Health Records ◽  
Prediction Models ◽  
Mode Of Delivery ◽  
Machine Learning Algorithms ◽  
Health Records ◽  
Electronic Health ◽  
Independent Cohort

Abstract: Identifying pregnancies at risk for preterm birth, one of the leading causes of worldwide infant mortality, has the potential to improve prenatal care. However, we lack broadly applicable methods to accurately predict preterm birth risk. The dense longitudinal information present in electronic health records (EHRs) is enabling scalable and cost-efficient risk modeling of many diseases, but EHR resources have been largely untapped in the study of pregnancy. Here, we apply machine learning to diverse data from EHRs to predict singleton preterm birth. Leveraging a large cohort of 35,282 deliveries, we find that a prediction model based on billing codes alone can predict preterm birth at 28 weeks of gestation (ROC-AUC=0.75, PR-AUC=0.40) and outperforms a comparable model trained using known risk factors (ROC-AUC=0.59, PR-AUC=0.21). Our machine learning approach is also able to accurately predict preterm birth sub-types (spontaneous vs. indicated), mode of delivery, and recurrent preterm birth. We demonstrate the portability of our approach by showing that the prediction models maintain their accuracy on a large, independent cohort (5,978 deliveries) with only a modest decrease in performance. Interpreting the features identified by the model as most informative for risk stratification demonstrates that they capture non-linear combinations of known risk factors and patterns of care. The strong performance of our approach across multiple clinical contexts and an independent cohort highlights the potential of machine learning algorithms to improve medical care during pregnancy.

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