scholarly journals The impact of dialysis therapy on older patients with advanced chronic kidney disease: a nationwide population-based study

BMC Medicine ◽  
2014 ◽  
Vol 12 (1) ◽  
Author(s):  
Chia-Jen Shih ◽  
◽  
Yung-Tai Chen ◽  
Shuo-Ming Ou ◽  
Wu-Chang Yang ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Older Patients ◽  
Population Based ◽  
Dialysis Therapy ◽  
Population Based Study ◽  
Advanced Chronic Kidney Disease ◽  
The Impact

scholarly journals Ischaemic stroke, haemorrhage, and mortality in older patients with chronic kidney disease newly started on anticoagulation for atrial fibrillation: a population based study from UK primary care

BMJ ◽  
2018 ◽  
pp. k342 ◽  
Author(s):  
Shankar Kumar ◽  
Simon de Lusignan ◽  
Andrew McGovern ◽  
Ana Correa ◽  
Mariya Hriskova ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Primary Care ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Ischaemic Stroke ◽  
Older Patients ◽  
Population Based ◽  
Population Based Study

scholarly journals Meglitinides increase the risk of hypoglycemia in diabetic patients with advanced chronic kidney disease: a nationwide, population-based study

Oncotarget ◽  
2017 ◽  
Vol 8 (44) ◽  
pp. 78086-78095 ◽  
Author(s):  
Pei-Chen Wu ◽  
Vin-Cent Wu ◽  
Cheng-Jui Lin ◽  
Chi-Feng Pan ◽  
Chih-Yang Chen ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Population Based ◽  
Diabetic Patients ◽  
Population Based Study ◽  
Advanced Chronic Kidney Disease

scholarly journals Association of Calcitriol Supplementation with Reduced COVID-19 Mortality in Patients with Chronic Kidney Disease: A Population-based Study

2021 ◽  
Author(s):  
Joaquim Oristrell ◽  
Joan C. Oliva ◽  
Isaac Subirana ◽  
Enrique Casado ◽  
Didier Dominguez ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Renal Function ◽  
Kidney Disease ◽  
Population Based ◽  
Inverse Association ◽  
Population Based Study ◽  
Advanced Chronic Kidney Disease ◽  
Beneficial Effects ◽  
Reduced Risk

Treatment with calcitriol, the hormonal form of vitamin D, has shown beneficial effects in ex-perimental models of acute lung injury. In this study we aimed to analyze the associations be-tween calcitriol supplementation and the risk of SARS-CoV2 infection or COVID-19 mortality. Individuals ≥18 years old living in Catalonia and supplemented with calcitriol from April 2019 to February 2020 were compared with propensity score matched controls. Outcome variables were SARS-CoV2 infection, severe COVID-19 and COVID-19 mortality. Associations between calcitriol supplementation and outcome variables were analyzed using multivariable Cox proportional regression. A total of 8076 patients were identified as being on calcitriol treatment. Advanced chronic kidney disease and hypoparathyroidism were the most frequent reasons for calcitriol supplementation in our population. Calcitriol use was associated with reduced risk of SARS-CoV2 infection (HR 0.78 [CI 95% 0.64-0.94], p=0.010), reduced risk of severe COVID-19 and reduced COVID-19 mortality (HR 0.57 (CI 95% 0.41-0.80), p=0.001) in patients with advanced chronic kidney disease. In addition, an inverse association between mean daily calcitriol dose and COVID-19 severity or mortality was observed in treated patients, independently of renal function. Our findings point out that patients with advanced chronic kidney disease could benefit from calcitriol supplementation during the COVID-19 pandemic.

P0820EMERGENCY DEPARTMENT UTILIZATION BY PATIENTS WITH ADVANCED CHRONIC KIDNEY DISEASE AND DIALYSIS: A POPULATION BASED STUDY

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Ruchi Chhibba ◽  
Silvia Leon-Mantilla ◽  
Thomas Ferguson ◽  
Paul Komenda ◽  
Navdeep Tangri ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Fold Increase ◽  
Population Based ◽  
Population Based Study ◽  
Advanced Chronic Kidney Disease ◽  
Gastrointestinal Complaints ◽  
Ed Visits ◽  
Winnipeg Regional Health Authority ◽  
Respiratory Complaints

Abstract Background and Aims Chronic Kidney Disease (CKD) is a potent risk factor for kidney failure, cardiovascular events and all cause hospitalizations. In addition to higher outpatient resource use, patients with CKD may present more frequently to the emergency department (ED) and may be more likely to be admitted for hospitalization. In Manitoba, we previously demonstrated an 8-fold increase in the frequency of ED presentations by patients on dialysis as compared to a non-dialysis population. Comparable data on ED visits remain sparse for patients with CKD G3-G5, not on dialysis. Here, we aim to describe the frequency of ED visits and highlight differences in reasons for visit in patients with CKD stages G3-G5 and Those on dialysis when compared to a non-renal population. Method We performed a retrospective cohort study using administrative health data from the Winnipeg Regional Health Authority, Canada. We included all adults (≥ 18 years) with CKD stages G3-G5 and patients undergoing dialysis between January 1st, 2010 and December 31, 2014. Secular trends in the in the rates of ED visits were calculated for those with CKD, those on dialysis and in the non-renal population. Results Over the study period, patients undergoing dialysis had the highest incidence of ED visits, followed by patients with CKD and those with normal kidney function (150 vs 106 vs 34 per 100 persons per year respectively). These rates were stable over the period studied. Among the non-renal population, the most common reasons for an ED visit were musculoskeletal complaints (25.6%), followed by gastrointestinal (11.04%) and cardiovascular complaints (10.26%). In the CKD and dialysis cohort, ED visits were more commonly secondary to cardiovascular complaints (21.54% and 18.99% respectively), followed by respiratory and gastrointestinal complaints. Admission to hospital was higher in CKD and dialysis populations than in the non-renal population (29.56%, 26.07% vs 10.61%, respectively). Conclusion Patients with CKD present frequently to the ED, and are often admitted after presentation. Cardiovascular and respiratory complaints are more common in the CKD population.

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