scholarly journals Prevalence of Plasmodium falciparum infection among pregnant women at first antenatal visit in post-Ebola Monrovia, Liberia

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Guillermo Martínez-Pérez ◽  
Dawoh Peter Lansana ◽  
Senga Omeonga ◽  
Himanshu Gupta ◽  
Bondey Breeze-Barry ◽  
...  
2019 ◽  
Vol 10 (2) ◽  
pp. 147
Author(s):  
Agholor Kin ◽  
Lucy F. Olusola ◽  
Idris Abubakar ◽  
Yakubu Mahmud

Plasmodium falciparum is the leading cause of malaria in pregnant women, a disease of public health importance especially in Nigeria where the infection is endemic. Hence, this study was conducted to ascertain the prevalent rate of Plasmodium falciparum infection among pregnant women attending antenatal in primary health care center, Wushishi Local Government, Niger state, Nigeria. 150 pregnant women were randomly selected and tested for P. falciparum using Plasmodium falciparum (05FK50) Rapid Diagnostic Test kit. The result obtained, revealed that 36 (24%) out of the 150 samples of the pregnant women were positive without any clinical manifestation of the infection. The result revealed that the prevalence rate was higher among women within 11-20 age group (43.8%) than those within 21-30 (17.4%) and 31 and above (9.0%). It was also observed from the study that prevalence rate was lower among women who use Insecticide Treated Net (6.5%) compared to those who does not (52.6%). Therefore the problem of Plasmodium falciparum infection in pregnant women should be prevented by the use of insecticide treated nets and effective case management with appropriate antimalarial drug during antenatal clinical visits.


Acta Tropica ◽  
2016 ◽  
Vol 153 ◽  
pp. 111-115 ◽  
Author(s):  
Ntoumi Francine ◽  
Bakoua Damien ◽  
Fesser Anna ◽  
Kombo Michael ◽  
Vouvoungui J. Christevy ◽  
...  

2003 ◽  
Vol 8 (2) ◽  
pp. 118-124 ◽  
Author(s):  
Frank P. Mockenhaupt ◽  
Jantina Mandelkow ◽  
Holger Till ◽  
Stephan Ehrhardt ◽  
Teunis A. Eggelte ◽  
...  

2018 ◽  
Vol 20 (2) ◽  
Author(s):  
Oluwasola O. Obebe ◽  
Olufarati O. Falohun ◽  
Olaitan O. Olajuyigbe ◽  
Mike A. Lawani ◽  
Olubunmi A. Ajayi

Background: Pregnant women in malaria-endemic areas are at high risk of Plasmodium falciparum infection and its complications. This study investigated the impact of asymptomatic P. falciparum on haematological parameters of pregnant women at first antenatal visit in south-western Nigeria.Methods: Hospital-based cross-sectional evaluation of 130 asymptomatic pregnant women was conducted. Plasmodium infection was diagnosed using Giemsa-stained blood smear microscopy and rapid diagnostic test, while haemoglobin levels (Hb), Packed Cell Volume (PCV), white blood cells (WBC) count, red blood cell (RBC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) were determined using semi-automated haematology analyser.Results: Multigravid pregnant women presented more during their second trimester. Overall malaria prevalence in the sampled population was 14.6%. Prevalence of malaria parasitaemia was highest (68.4%) in the second trimester. P. falciparum infected pregnant women had significantly lower mean values of packed cell volume (PCV), haematocrit (Hb), and total white blood cell (WBC) compared to non-infected  individuals  (t = -4.07, p= 0.001; t = 3.30, p = <0.001; t = -2.77, p <0.001).Conclusion: There is asymptomatic P. falciparum infection in the study area and this may form a reservoir for transmission. Pregnant women infected with malaria parasites exhibited important changes in haematocrit level, haemoglobin concentration, and total white blood cells. Use of anti-malaria therapy and insecticide-treated bed net would result in greater haematological benefits.


Author(s):  
Michael P.H. Vleugels ◽  
Bernard Brabin ◽  
Wijnand M.C. Eling ◽  
Ruurd De Graaf

2012 ◽  
Vol 45 (3) ◽  
pp. 369-374 ◽  
Author(s):  
Paulo Adão Campos ◽  
Bianor Valente ◽  
Rosa Bessa Campos ◽  
Luzia Gonçalves ◽  
Virgílio Estóliodo Rosário ◽  
...  

INTRODUCTION: Malaria during pregnancy remains a serious public health problem. The aim of this study was to establish the prevalence and possible risk factors for malaria in pregnant women attending antenatal care at Augusto Ngangula Specialized General Hospital in Luanda, Angola. METHODS: Pregnant women (679 total) who attended antenatal care from April to September 2008 were included in the study after signing informed consent. For each participant, the social-demographic profile and malaria and obstetric histories were investigated via a questionnaire. Diagnosis was made by optic microscopy, and hemoglobin concentration measured. The associations between age, parity, gestational age, residence, schooling, malaria during gravity, anemia and treatment with incidence of Plasmodium falciparum infection were analyzed through logistic regression. RESULTS: During the period of study, 74 (10.9%) out of 679 women were infected by P. falciparum. The average concentration of hemoglobin was 11.1 ± 0.07g/dL, and there were significant associations between the history of malaria during pregnancy, P. falciparum infection (p<0.01) and anemia at the time of observation (p<0.001). CONCLUSIONS: Previous history of malaria during pregnancy represents a risk factor for current infection and anemia was an important complication associated with malaria, even in women who were treated with sulfadoxine-pyrimethamine during pregnancy.


Author(s):  
Susi W Saragih ◽  
St. Maisuri T. Chalid ◽  
Umar Malinta ◽  
Isra Wahid

Objective: To determine the effect of artesunate on peripheral parasitaemia in pregnant women with Plasmodium falciparum infection. Methods: Pregnant women in second and third trimester with Plasmodium falciparum infection and their newborns were included in cohort prospective study in Sorong West Papua from September 2015 to February 2016. All pregnant women received 200 mg orally artesunate monotherapy for 7 days. Their newborns examined for weight at delivery and parasitaemia in placenta and cord blood. Parasitaemia diagnosis by Rapid Diagnostic Test and blood smear microscopy. Results: After artesunatemonotherapy, 82.5% (33/40) malariainfected pregnant women had negative parasitaemia (p=0.000) although 17.5% (7/40) of the pregnant women had positive parasitaemia. Parasitaemia also found in 10% (4/40) of placenta and 7.5% (3/40) of umbilical cord from newborns of malaria-infected pregnant women treated with artesunate. 70% (28/40) of the newborns in this study had normal weight. Conclusion: Artesunate reduces peripheral parasitaemia in the second and third trimester of pregnancy, and is associated with normal birth weight. [Indones J Obstet Gynecol 2017; 5-3: 135-138] Keywords: artesunate, low birth weight, peripheral parasitaemia


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