scholarly journals Impact of asymptomatic Plasmodium falciparum on haematological parameters of pregnant women at first antenatal visit in South-western Nigeria

2018 ◽  
Vol 20 (2) ◽  
Author(s):  
Oluwasola O. Obebe ◽  
Olufarati O. Falohun ◽  
Olaitan O. Olajuyigbe ◽  
Mike A. Lawani ◽  
Olubunmi A. Ajayi

Background: Pregnant women in malaria-endemic areas are at high risk of Plasmodium falciparum infection and its complications. This study investigated the impact of asymptomatic P. falciparum on haematological parameters of pregnant women at first antenatal visit in south-western Nigeria.Methods: Hospital-based cross-sectional evaluation of 130 asymptomatic pregnant women was conducted. Plasmodium infection was diagnosed using Giemsa-stained blood smear microscopy and rapid diagnostic test, while haemoglobin levels (Hb), Packed Cell Volume (PCV), white blood cells (WBC) count, red blood cell (RBC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) were determined using semi-automated haematology analyser.Results: Multigravid pregnant women presented more during their second trimester. Overall malaria prevalence in the sampled population was 14.6%. Prevalence of malaria parasitaemia was highest (68.4%) in the second trimester. P. falciparum infected pregnant women had significantly lower mean values of packed cell volume (PCV), haematocrit (Hb), and total white blood cell (WBC) compared to non-infected  individuals  (t = -4.07, p= 0.001; t = 3.30, p = <0.001; t = -2.77, p <0.001).Conclusion: There is asymptomatic P. falciparum infection in the study area and this may form a reservoir for transmission. Pregnant women infected with malaria parasites exhibited important changes in haematocrit level, haemoglobin concentration, and total white blood cells. Use of anti-malaria therapy and insecticide-treated bed net would result in greater haematological benefits.

Author(s):  
Y. Garba ◽  
E. A. Adeola

An experiment was carried out to test the effect of Sesame residue (SR) inclusion in the diets of growing Yankasa ram lambs on haematological and serum biochemical parameters. Twelve (12) Yankasa ram lambs with initial body weight of 20.08±3.08kg were allotted to three dietary treatments containing 0, 20 and 30% SR (A, B and C). A completely randomized design was used for the study which lasted twelve (12) weeks. The haemetology results revealed that the white blood cells (12.85-16.85 109/L), red blood cells (1.49-2.04 1012/L), haemoglobin, mean corpuscular haemoglobin concentration (MCHC), mean corpuscular haemoglobin (MCH) (39.85-48.00 pg), mean corpuscular volume (MCV) and lymphocytes differed significantly (P<0.05) among the treatments. Lambs fed 30% SR had the highest MCV, MCH, MCHC and lymphocyte values. Serum biochemical analysis results revealed that lambs fed 20% and 30% SR had higher alkaline phosphatase, total protein and globulin values than lambs fed 0%SR. However, SR inclusion in the diets did not affect calcium and phosphorus levels of the lambs. In conclusion, including sesame residue at 30% in the diets of growing Yankasa ram lambs had no observable adverse effect on haematological and serum biochemical parameters.


2021 ◽  
Vol 14 (1) ◽  
pp. e3789
Author(s):  
Musa Idi-Ogede Abubakar ◽  
Adeshina Ibrahim

Introduction: Macrocytic-normochromic anaemia was induced in Clarias gariepinus at intervals of 1, 7 and 14 days. Experimental fish were exposed to test water separately diluted with sub-lethal concentrations of paraquat of 0, 0.03, 0.05, 0.07 and 0.09mg/L. 14 days. No in-depth work has been carried out on Macrocytic-normochromic anaemia in Nigeria. Objective: to evaluate macrocytic-normochromic anaemia in Clarias gariepinus exposed to sublethal concentrations of paraquat. Methods: Blood were collected at intervals of 1, 7 and 14 days .Results: Blood dyscrasias  was observed with a significant (p<0.05) decrease in haemoglobin, haematocrit, red blood cells, white blood cells, lymphocytes and   monocytes. Mean corpuscular volume (MCV), Mean corpuscular haemoglobin (MCH), Neutrophils, Eosinophil and Basophil increased significantly (p<0.05) with increasing concentrations of the toxicant while Mean corpuscular haemoglobin concentration (MCHC) remained normal. Conclusion: Sublethal concentrations of paraquat induced macrocytic-normochromic anaemia in the exposed Clarias gariepinus.


2013 ◽  
Vol 22 (2) ◽  
pp. 127-134
Author(s):  
AFM Nazmus Salehin ◽  
Shankar Chandra Mandal

Haematological profile of air breathing mud eel, Monopterus cuchia (Hamilton) from Mymensinghh and Kishoreganj were determined in the present study. Erythrocytes, lymphocytes, monocytes, neutrophils, eosinophils and platelet were evaluated. Significantly higher (p < 0.05) haemoglobin (Hb) concentration was found in air breathing mud eel of Kishoreganj than that of Mymensinghh area. The haematocrit (HCT), erythrocyte sedimentation rate (ESR), total red blood cells (TRBC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), total white blood cells (TWBC), lymphocytes, neutrophils, monocytes, eosinophils did not show any significant difference. Findings of the present study showed little variation of haematological profile in air breathing mud eel sampled from Mymensinghh and Kishoreganj. Dhaka Univ. J. Biol. Sci. 22(2): 127-134, 2013 (July)


2018 ◽  
Vol 66 (4) ◽  
pp. 530-541 ◽  
Author(s):  
Ana Cristina Silvestre-Ferreira ◽  
Mário Cotovio ◽  
Mário Maia ◽  
Felisbina Queiroga ◽  
M João Pires ◽  
...  

The Lusitano horse is an autochthonous Portuguese breed with a growing worldwide expansion. Our objective was to establish reference intervals for haematological parameters using the haematological cell counter LaserCyte (IDEXX). For this purpose, blood samples from 100 healthy adult horses (13 females and 87 males, ranging from 3 to 25 years of age) were analysed. The reference intervals were estimated following the ASVCP guidelines with the Reference Value Advisor software. The obtained reference intervals were 6.4–10.1 × 1012/L for red blood cells, 30.6–45.1% for haematocrit, 11.6–17.1 g/dL for haemoglobin, 42.8–53.2 fL for mean corpuscular volume (MCV), 15.5–20.8 pg for mean corpuscular haemoglobin (MCH), 33.7–39.4 g/dL for mean corpuscular haemoglobin concentration, 17.8–20.3% for red cell distribution width (RDW), 4.5–10.1 × 109/L for white blood cells, 2.2–6.0 × 109/L for neutrophils, 0.9–4.9 × 109/L for lymphocytes, 0.2–0.5 × 109/L for monocytes, 0.1–0.6 × 109/L for eosinophils, 0.0–0.1 × 109/L for basophils, 78.5–172.2 K/mL for platelets, 4.3–9.4 fL for mean platelet volume, 18.8–24.2% for platelet distribution width, and 0.06–0.12% for plateletcrit. LaserCyte equine reference intervals are transferable to the Lusitano horse for 18 of the 22 analytes studied. Regarding age, significant statistical differences were observed for MCV, RDW, neutrophils and lymphocytes between the mean values of young (3–6 years old), middle-aged (7–14 years old) and old (< 15 years old) age groups. MCH means were statistically significantly different between the three age groups. The haematological reference intervals established in this study might represent a valuable and applicable tool for haematological assessment of adult Lusitano horses, providing useful information that helps clinicians to interpret clinical data.


2021 ◽  
Vol 13 (2) ◽  
pp. 72-78
Author(s):  
H. M. Ibrahim ◽  
I. Bulama ◽  
S. Bashir ◽  
S. I. Abubakar ◽  
W. Ali

Camels are regarded as the ship of the desert, being used for transporting humans and their goods. They are also raised for milk, meat, hides and wool. Normal haematological values are important as disease diagnostic aid as they are vital indicator of the animals’ health status. Haematological parameters of one- humped camels (Camelusdromedarius) were determined in this study. 60 one- humped camels (Camelusdromedarius) were selected in sokoto and their blood samples were analyze using standard procedures for haematological parameters. [Packed cell volume (PCV), red blood cells (RBC), haemoglobin (Hb),white blood cells (WBC), neutrophils, eosinophils, Basophils, monocyte, lymphocyte, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), and mean corpuscular haemoglobin concentration (MCHC)].For all the parameters, only neutrophils and MCV values showed significant variation between sexes with male camels having higher values than females. There is variation in the range values for all the parameters between sexes except Basophils, Monocyte and Lymphocyte. Based on the results of this study, the values were similar in both sex except in neutrophils and mean corpuscular volume indicating insignificant effect of sex on most of the haematological parameters.


2021 ◽  
Vol 2 (1) ◽  
pp. 53-64
Author(s):  
Sunardi Sunardi ◽  
Kabul Fadilah ◽  
Nadia Istiqomah ◽  
Miranti Ariyani ◽  
Desak Made Malini ◽  
...  

Severe river pollution creates a stressful environment for aquatic organisms, causing disturbances to their health and leading to their extinction. Thus, in this study, the stress responses of tolerant (Oreochromis niloticus) and sensitive (Cyprinus carpio) fish to river pollution in the Citarum River, Indonesia were investigated. The two groups of fish were exposed to varying levels and lengths of water pollution, their blood was sampled, and stress responses were identified. The red blood cells (RBC) count, haemoglobin (HGB), haematocrit (HCT), white blood cells (WBC) count, blood glucose levels, and derived haematological indices such as mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC), were measured. Significant changes in these indices, with tendential changes in RBC and HCT, were observed, indicating that stress responses had occurred in both groups of fish. The sensitive fish recorded more pronounced changes in their haematological activities, with greater amounts of blood parameters being altered in response to water pollution exposure. This result suggested that the sensitive fish were more susceptible to environmental stressors and were, therefore, more vulnerable to extinction in a polluted natural environment.


2021 ◽  
Vol 6 (3) ◽  
pp. 56-64
Author(s):  
Stella B. Egbe ◽  
Patience A. Akpan ◽  
Euphoria C. Akwiwu ◽  
Josephine O. Akpotuzor

Pre-eclampsia is a gestational complication with immense outcomes on foetal/ infant and maternal health. This study assessed haematological variables of pre-eclamptic pregnant women receiving antenatal care at University of Calabar Teaching Hospital (UCTH), Calabar. Following due ethical considerations, 90 subjects aged 18-45 years were enrolled. They comprised 30 pre-eclamptic patients admitted into the antenatal ward, UCTH; 30 pregnant women with no medical condition attending antenatal clinic, UCTH and 30 apparently healthy non-pregnant women of same age range as control subjects. Weight, height and blood pressure were measured while a pre-tested structured questionnaire was used to obtain demographic data. Packed cell volume (PCV), haemoglobin (HB), red blood cell count (RBC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), white blood cell count (WBC) with differentials, platelet count and mean platelet volume (MPV) were determined using Sysmex Haematology autoanalyzer (Sysmex, Japan). Significantly lower (p<0.05) PCV, HB, MCV and platelet count were recorded among pre-eclamptic patients compared to the pregnant and non-pregnant controls. Conversely, body mass index, blood pressures, MCHC, WBC and MPV of pre-eclamptic patients were significantly higher (p<0.05) compared to pregnant and non-pregnant controls. There were also significant differences (p<0.05) in RBC and differential white cell count among the three groups. Also, we observed appearance of protein in urine associated with increased blood pressure. It is concluded that haematological changes occur in pre-eclampsia and these changes reflect the bodys response to systemic inflammation induced by pregnancy and amplified by the presence of hypertension.


2017 ◽  
Vol 62 (No. 7) ◽  
pp. 401-405 ◽  
Author(s):  
F. Fazio ◽  
V. Ferrantelli ◽  
C. Saoca ◽  
G. Giangrosso ◽  
G. Piccione

The aim of this study was to investigate the influence of storage time at +4 °C on haematological indicators in rainbow trout Oncorhynchus mykiss (Walbaum, 1792). For this purpose, 60 Italian trout were evaluated and red blood cells, white blood cells, thrombocyte count, haematocrit, haemoglobin concentration, mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration were determined. After blood collection (T<sub>0</sub>), all samples were immediately analysed using an automatic method to assess the haematological parameters and then divided into two different aliquots and stored at +4 °C. The first aliquot was refrigerated for 168 h (T<sub>1</sub>), the second one for 336 h (T<sub>2</sub>). Statistical analysis (one-way repeated-measures ANOVA) showed a significant effect of storage time (P &lt; 0.05) on red blood cells, thrombocyte count, haematocrit, haemoglobin concentration, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration. The obtained data expand our knowledge of haematological evaluation techniques and could contribute to the development of an appropriate method for haematological analysis that is suitable for the evaluation of the health status of wild and farmed fish.


2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Guillermo Martínez-Pérez ◽  
Dawoh Peter Lansana ◽  
Senga Omeonga ◽  
Himanshu Gupta ◽  
Bondey Breeze-Barry ◽  
...  

2017 ◽  
Vol 25 (1) ◽  
pp. 27 ◽  
Author(s):  
V. Šimek ◽  
D. Zapletal ◽  
E. Straková ◽  
A. Pavlík ◽  
P. Suchý

<p>The aim of the present study was to evaluate the effect of breed on haematological and biochemical indicators in 3 dwarf rabbit breeds. In the experiment, 30 sexually intact dwarf rabbit females aged 6 mo were used. With the sole exception of white blood cells and haematocrit value, breed had the most significant effect on the majority of haematological indicators monitored. The red blood cell count was higher in the Dwarf Lop compared to the Netherland Dwarf (+1.91×10<sup>12</sup> cells/L; P&lt;0.05) and also the Teddy Dwarf (+1.32×10<sup>12</sup> cells/L; P&lt;0.05). For haemoglobin concentration, a higher value was found in the Netherland Dwarf than in the Teddy Dwarf (+39.29 g/L; P&lt;0.05) and the Dwarf Lop (+26.36 g/L; P&lt;0.05). For erythrocytic indicators, the highest values of mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration were found in the Netherland Dwarf. The breed had a significant effect on the urea and potassium values. A higher value of urea was recorded in the Dwarf Lop compared to the Teddy Dwarf (+1.56 mmol/L; P&lt;0.05). For potassium, a higher value was found in the Netherland Dwarf compared to the Teddy Dwarf (+0.85 mmol/L; P&lt;0.05). In addition, a significantly positive correlation (P&lt;0.05) was found between the live weight of dwarf females and values of haematocrit (0.49), albumin (0.54), alanine aminotransferase (0.51), and aspartate aminotransferase (0.41), while a significantly negative correlation (P&lt;0.05) was found between their live weight and values of triacylglycerols (–0.44), alkaline phosphatase (–0.38) and inorganic phosphorus (–0.52). </p>


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