scholarly journals The reliability and validity of the Patient Health Questionnaire-9 (PHQ-9) and PHQ-2 in patients with infertility

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Saman Maroufizadeh ◽  
Reza Omani-Samani ◽  
Amir Almasi-Hashiani ◽  
Payam Amini ◽  
Mahdi Sepidarkish
Keyword(s):  
Depressive Symptoms ◽  
Internal Consistency ◽  
Convergent Validity ◽  
Univariate Analysis ◽  
Reliability And Validity ◽  
Well Being ◽  
Patient Health Questionnaire ◽  
Depression Symptoms ◽  
Health Questionnaire ◽  
Patient Health

Abstract Background Depression in patients with infertility often goes undiagnosed and untreated. The Patient Health Questionnaire-9 (PHQ-9) and its ultra-brief version (i.e. PHQ-2) are widely used measures of depressive symptoms. These scales have not been validated in patients with infertility. The aim of the present study was to examine the reliability and validity of the PHQ-9 and PHQ-2 in patients with infertility. Methods In this cross-sectional study, a total of 539 patients with infertility from a referral infertility clinic in Tehran, Iran completed the PHQ-9, along with other relevant scales: the WHO-five Well-being Index (WHO-5), the Hospital Anxiety and Depression Scale (HADS), and the Generalized Anxiety Disorder-7 (GAD-7). Factor structure and internal consistency of PHQ-9 were examined via confirmatory factor analysis (CFA) and Cronbach’s alpha, respectively. Convergent validity was evaluated by relationship with WHO-5, HADS and GAD-7. Results The mean total PHQ-9 and PHQ-2 scores were 8.47 ± 6.17 and 2.42 ± 1.86, respectively, and using a cut-off value of 10 (for PHQ-9) and 3 (for PHQ-2), the prevalence of depressive symptoms was 38.6 and 43.6%, respectively. The Cronbach’s alphas for PHQ-9 and PHQ-2 were, respectively, 0.851 and 0.767, indicating good internal consistency. The CFA results confirmed the one-factor model of the PHQ-9 (χ2/df = 4.29; CFI = 0.98; RMSEA = 0.078 and SRMR = 0.044). Both PHQ-9 and PHQ-2 showed moderate to strong correlation with the measures of WHO-5, HADS-depression, HADS-anxiety, and the GAD-7, confirming convergent validity. In univariate analysis, female sex, long infertility duration, and unsuccessful treatment were significantly associated with depression symptoms. Conclusion Both PHQ-9 and PHQ-2 are brief and easy to use measures of depressive symptoms with good psychometric properties that appear suitable for routine use in patients with infertility.

scholarly journals Validation and calibration of the patient health questionnaire (PHQ-9) in Argentina

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
María Urtasun ◽  
Federico Manuel Daray ◽  
Germán Leandro Teti ◽  
Fernando Coppolillo ◽  
Gabriela Herlax ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Convergent Validity ◽  
Patient Health Questionnaire ◽  
Receiver Operating Curve ◽  
Local Version ◽  
Health Questionnaire ◽  
Good Ability ◽  
Patient Health ◽  
Severity Of Depression ◽  
Degrees Of Severity

Abstract Background The Patient Health Questionnaire-9 (PHQ-9) is a brief tool to assess the presence and severity of depressive symptoms. This study aimed to validate and calibrate the PHQ-9 to determine appropriate cut-off points for different degrees of severity of depression in Argentina. Methods We conducted a cross-sectional study on an intentional sample of adult ambulatory care patients with different degrees of severity of depression. All patients who completed the PHQ-9 were further interviewed by a trained clinician with the Mini International Neuropsychiatric Interview (MINI) and the Beck Depression Inventory-II (BDI-II). Reliability and validity tests, including receiver operating curve analysis, were performed. Results One hundred sixty-nine patients were recruited with a mean age of 47.4 years (SD = 14.8), of whom 102 were females (60.4%). The local PHQ-9 had high internal consistency (Cronbach’s alpha = 0.87) and satisfactory convergent validity with the BDI-II scale [Pearson’s correlation = 0.88 (p < 0.01)]. For the diagnosis of Major Depressive Episode (MDE) according to the MINI, a PHQ-9 ≥ 8 was the optimal cut-off point found (sensitivity 88.2%, specificity 86.6%, PPV 90.91%). The local version of PHQ-9 showed good ability to discriminate among depression severity categories according to the BDI-II scale. The best cut off points were 6–8 for mild cases, 9–14 for moderate and 15 or more for severe depressive symptoms respectively. Conclusions The Argentine version of the PHQ-9 questionnaire has shown acceptable validity and reliability for both screening and severity assessment of depressive symptoms.

The WHO-5 Well-Being Index: A Validation Study in People with Infertility

2020 ◽  
Author(s):  
Reza OMANI-SAMANI ◽  
Saman MAROUFIZADEH ◽  
Amir ALMASI-HASHIANI ◽  
Mahdi SEPIDARKISH ◽  
Payam AMINI
Keyword(s):  
Internal Consistency ◽  
Convergent Validity ◽  
Depression Scale ◽  
Reliability And Validity ◽  
Public Health Problem ◽  
Well Being ◽  
Cronbach’S Alpha ◽  
Cronbach's Alpha ◽  
Prevalence Of Depression ◽  
Patient Health

Background: Infertility is a public health problem and can lead to depressive symptoms. In recent years, the WHO-five Well-being Index (WHO-5) has been used as a screening measure for depression, but study on psychometric properties in people with infertility is scarce. The objective of this study was to examine the reliability and validity of the Persian version of the WHO-5 in people with infertility. Methods: Overall, 539 infertile patients from a referral infertility center in Tehran, Iran in the period between May and Aug 2017, completed the WHO-5, along with other psychological measures: the Patient Health Questionnaire-9 (PHQ-9) and the Hospital Anxiety and Depression Scale (HADS). Construct validity and internal consistency of WHO-5 were evaluated using confirmatory factor analysis (CFA) and Cronbach’s alpha, respectively. Convergent validity was examined by relationship with PHQ-9 and HADS. Results: The prevalence of poor well-being was 44.3% and that of depression was 18.6%. CFA confirmed the unidimensional factor structure of the WHO-5. Internal consistency of the WHO-5 was good (Cronbach’s alpha=0.858). The WHO-5 significantly correlated with the PHQ-9 (r=-0.522), HADS-anxiety (r=-0.524) and HADS-depression (r=-0.630), confirming convergent validity. Conclusion: The WHO-5 is a short and easy to use questionnaire with satisfactory reliability and validity that appears suitable for use as a screening test for depressive symptom in infertile people. In addition, the prevalence of depression and poor well-being was very high in this population.

scholarly journals Reliability and construct validity of the modified Finnish version of the 9-item Patient Health Questionnaire, and its’ content validity within biopsychosocial frame among female healthcare workers with sub-acute or recurrent LBP

2019 ◽  
Author(s):  
Jaana Helena Suni ◽  
Tarja Virkkunen ◽  
Pauliina Husu ◽  
Kari Tokola ◽  
Jari Parkkari ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Construct Validity ◽  
Internal Consistency ◽  
Content Validity ◽  
Healthcare Workers ◽  
Bodily Pain ◽  
Patient Health Questionnaire ◽  
Health Questionnaire ◽  
Increased Risk ◽  
Patient Health

Abstract Background: Healthcare workers have increased risk for chronic low back pain (LBP) leading to reduced workability. Depression, a highly prevalent, costly and disabling condition, is commonly seen in patients with sub-acute LBP. This study investigated the psychometric properties and content-validity of a modified 9-item Patient Health Questionnaire (PHQ-9-mFIN) in female healthcare workers with sub-acute LBP. Methods: Reliability (internal consistency, test-retest repeatability) was assessed with standard methods. Construct validity of the PHQ-9-mFIN was assessed as level of depression (PHQ-9-mFIN: 0-4 none, 5-9 mild, ≥10 at least moderate) against RAND-36 Health Survey, a valid measure of health-related quality of life (HRQoL). Content validity was determined as the strength of the association between the levels of PHQ-9-mFIN and the selected biopsychosocial factors. Results: The internal consistency of the PHQ-9-mFIN was high (Cronbach’s α=0.82) and the test-retest repeatability scores (n=65) fair: Pearson’s correlation 0.76, Kappa-value 0.42 for the diagnostic criterion (i.e. scores 0-9 vs. 10-27). Construct validity (Spearman correlation) against the Physical and Mental component items and their summary scales of the RAND 36 were much higher for the Mental (range -0.43 to -0.70 and -0.68) than for the Physical (range -0.06 to -0.41 and -0.24), respectively. There was a clear stepwise association (p<0.001) between the levels of depressive symptoms and General health (physical component, range 59.1 to 78.8). The associations with all items of the Mental components were strong and graded (p<0.001). All participants had low scores for Bodily pain regardless of the level of depressive symptoms. There was a strong association (p≤0.003) between levels of PHQ-9-mFIN and multisite pain, lumbar exertion and recovery after work days, neuromuscular fitness in Modified push-ups, workability, and fear of pain related to work. Conclusions: The PHQ-9-mFIN showed adequate reliability, and excellent construct and content validity among female healthcare workers with recurrent LBP and physically strenuous work. Trial registration: NCT01465698

scholarly journals Direct Participation in and Indirect Exposure to the Occupy Central Movement and Depressive Symptoms: A Longitudinal Study of Hong Kong Adults

2016 ◽  
Vol 184 (9) ◽  
pp. 636-643 ◽  
Author(s):  
Michael Y. Ni ◽  
Tom K. Li ◽  
Herbert Pang ◽  
Brandford H. Y. Chan ◽  
Betty Y. Yuan ◽  
...  
Keyword(s):  
Hong Kong ◽  
Depressive Symptoms ◽  
Major Depression ◽  
Patient Health Questionnaire ◽  
Health Questionnaire ◽  
Personal Involvement ◽  
Patient Health ◽  
Population Mental Health ◽  
History Of ◽  
Occupy Central

Abstract Despite the extensive history of social movements around the world, the evolution of population mental health before, during, and after a social movement remains sparsely documented. We sought to assess over time the prevalence of depressive symptoms during and after the Occupy Central movement in Hong Kong and to examine the associations of direct and indirect exposures to Occupy Central with depressive symptoms. We longitudinally administered interviews to 909 adults who were randomly sampled from the population-representative FAMILY Cohort at 6 time points from March 2009 to March 2015: twice each before, during, and after the Occupy Central protests. The Patient Health Questionnaire-9 was used to assess depressive symptoms and probable major depression (defined as Patient Health Questionnaire-9 score ≥10). The absolute prevalence of probable major depression increased by 7% after Occupy Central, regardless of personal involvement in the protests. Higher levels of depressive symptoms were associated with online and social media exposure to protest-related news (incidence rate ratio (IRR) = 1.28, 95% confidence interval (CI): 1.06, 1.55) and more frequent Facebook use (IRR = 1.38, 95% CI: 1.12, 1.71). Higher levels of intrafamilial sociopolitical conflict was associated with more depressive symptoms (IRR = 1.05, 95% CI: 1.01, 1.09). The Occupy Central protests resulted in substantial and sustained psychological distress in the community.

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