Inhibition of the mechanistic target of rapamycin induces cell survival via MAPK in tuberous sclerosis complex

Target Of Rapamycin ◽

Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy

Autophagy ◽

10.4161/auto.22791 ◽

2013 ◽

Vol 9 (2) ◽

pp. 175-195 ◽

Cited By ~ 73

Author(s):

He Huang ◽

Rongyan Kang ◽

Ji Wang ◽

Guangxiang Luo ◽

Wei Yang ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Endoplasmic Reticulum Stress ◽

Tuberous Sclerosis ◽

Mtor Pathway ◽

Target Of Rapamycin ◽

Tuberous Sclerosis Complex 1–Mechanistic Target of Rapamycin Complex 1 Signaling Determines Brown-to-White Adipocyte Phenotypic Switch

Diabetes ◽

10.2337/db14-0427 ◽

2014 ◽

Vol 64 (2) ◽

pp. 519-528 ◽

Cited By ~ 29

Author(s):

Xinxin Xiang ◽

He Lan ◽

Hong Tang ◽

Fang Yuan ◽

Yanhui Xu ◽

...

Keyword(s):

Tuberous Sclerosis ◽

Target Of Rapamycin ◽

Phenotypic Switch ◽

White Adipocyte ◽

Hypothalamic orexin and mechanistic target of rapamycin activation mediate sleep dysfunction in a mouse model of tuberous sclerosis complex

Neurobiology of Disease ◽

10.1016/j.nbd.2019.104615 ◽

2020 ◽

Vol 134 ◽

pp. 104615 ◽

Cited By ~ 2

Author(s):

Bo Zhang ◽

Dongjun Guo ◽

Lirong Han ◽

Nicholas Rensing ◽

Akiko Satoh ◽

...

Keyword(s):

Mouse Model ◽

Tuberous Sclerosis ◽

Target Of Rapamycin ◽

Sleep Dysfunction ◽

Eccentric contractions increase the phosphorylation of tuberous sclerosis complex-2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome

The Journal of Physiology ◽

10.1113/jphysiol.2013.256339 ◽

2013 ◽

Vol 591 (18) ◽

pp. 4611-4620 ◽

Cited By ~ 53

Author(s):

Brittany L. Jacobs ◽

Jae-Sung You ◽

John W. Frey ◽

Craig A. Goodman ◽

David M. Gundermann ◽

...

Keyword(s):

Tuberous Sclerosis ◽

Target Of Rapamycin ◽

Eccentric Contractions ◽

Dermatological adverse events associated with use of oral mechanistic target of rapamycin inhibitors in a cohort of individuals with tuberous sclerosis complex

British Journal of Dermatology ◽

10.1111/bjd.19124 ◽

2020 ◽

Vol 183 (3) ◽

pp. 588-589 ◽

Cited By ~ 1

Author(s):

D.J. Pithadia ◽

A.M. Treichel ◽

A.M. Jones ◽

P. Julien‐Williams ◽

T. Machado ◽

...

Keyword(s):

Adverse Events ◽

Tuberous Sclerosis ◽

Target Of Rapamycin ◽

GADD34 inhibits mammalian target of rapamycin signaling via tuberous sclerosis complex and controls cell survival under bioenergetic stress

International Journal of Molecular Medicine ◽

10.3892/ijmm.19.3.475 ◽

2007 ◽

Cited By ~ 1

Author(s):

Ryosuke Watanabe ◽

Yukihiro Tambe ◽

Hirokazu Inoue ◽

Takahiro Isono ◽

Masataka Haneda ◽

...

Keyword(s):

Cell Survival ◽

Tuberous Sclerosis ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin

Cannabidiol Elevates Mechanistic Target of Rapamycin Inhibitor Levels in Patients With Tuberous Sclerosis Complex

Pediatric Neurology ◽

10.1016/j.pediatrneurol.2019.11.017 ◽

2020 ◽

Vol 105 ◽

pp. 59-61 ◽

Cited By ~ 4

Author(s):

Daniel Ebrahimi-Fakhari ◽

Karen D. Agricola ◽

Cynthia Tudor ◽

Darcy Krueger ◽

David Neal Franz

Keyword(s):

Tuberous Sclerosis ◽

Target Of Rapamycin ◽

Mechanistic Target of Rapamycin (mTOR) in Tuberous Sclerosis Complex-Associated Epilepsy

Pediatric Neurology ◽

10.1016/j.pediatrneurol.2014.10.028 ◽

2015 ◽

Vol 52 (3) ◽

pp. 281-289 ◽

Cited By ~ 74

Author(s):

Paolo Curatolo

Keyword(s):

Tuberous Sclerosis ◽

Target Of Rapamycin ◽

Tuberous sclerosis complex tumor suppressor 1 (TSC1); TSC2; mammalian target of rapamycin (mTOR; FRAP; RAFT1)

Science-Business eXchange ◽

10.1038/scibx.2012.919 ◽

2012 ◽

Vol 5 (35) ◽

pp. 919-919

Keyword(s):

Tumor Suppressor ◽

Tuberous Sclerosis ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin

Tuberous Sclerosis Complex Suppression in Cerebellar Development and Medulloblastoma: Separate Regulation of Mammalian Target of Rapamycin Activity and p27Kip1 Localization

Cancer Research ◽

10.1158/0008-5472.can-09-1299 ◽

2009 ◽

Vol 69 (18) ◽

pp. 7224-7234 ◽

Cited By ~ 28

Author(s):

Bobby Bhatia ◽

Paul A. Northcott ◽

Dolores Hambardzumyan ◽

Baskaran Govindarajan ◽

Daniel J. Brat ◽

...

Keyword(s):

Tuberous Sclerosis ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin ◽

Cerebellar Development