scholarly journals Umbilical cord blood acid-base analysis and the development of significant hyperbilirubinemia in near-term and term newborns: a cohort study

2017 ◽  
Vol 43 (1) ◽  
Author(s):  
Vincenzo Zanardo ◽  
Federico de Luca ◽  
Alphonse K. Simbi ◽  
Matteo Parotto ◽  
Pietro Guerrini ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Acid Base ◽  
Base Analysis ◽  
Term Newborns ◽  
Near Term

scholarly journals Effect of Chorionicity on Umbilical Cord Blood Acid-Base Analysis of the Second Twin

2020 ◽  
Vol 23 (3) ◽  
pp. 178-183
Author(s):  
Matthew J. Blitz ◽  
Burton Rochelson ◽  
Nontawan Benja-Athonsirikul ◽  
Weiwei Shan ◽  
Meir Greenberg ◽  
...  
Keyword(s):  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Tertiary Hospital ◽  
Chronic Hypertension ◽  
Acid Base ◽  
Arterial Ph ◽  
Vaginal Deliveries ◽  
Twin Pregnancies ◽  
Second Twin

AbstractOur objective was to determine whether chorionicity affects umbilical cord blood acid-base parameters of the second twin. This was a retrospective cohort of twin pregnancies delivered at ≥23 weeks of gestation at a tertiary hospital from 2010 to 2016. Patients were included if arterial and venous umbilical cord gas results were available for both newborns and chorionicity was confirmed histologically. Exclusion criteria included intrauterine fetal demise of either twin prior to labor, major fetal anomalies, monoamnionicity, uncertain chronicity and twin-to-twin transfusion syndrome. The primary outcome evaluated was the umbilical artery (UA) pH of the second twin. A total of 593 dichorionic (DC) and 86 monochorionic (MC) twin pregnancies were included. No difference in UA pH was observed between MC and DC twins. Among vaginal deliveries (n = 97), the UA pH of the first twin was higher than the second twin (7.26 vs. 7.24; p = .01). Twin-to-twin delivery interval (TTDI) ≥20 min was associated with a higher UA pH in the first twin compared to the second twin (7.25 vs. 7.16, respectively; p = .006). Multivariable logistic regression was used to predict arterial pH < 7.20 for the second twin; the most predictive factors were arterial pH < 7.20 for the first twin, chronic hypertension and prolonged TTDI. Chorionicity was not associated with any acid-base parameter of umbilical cord blood in either the first or second twin. No differences in neonatal outcomes were observed based on chorionicity or birth order. Populations with a lower cesarean delivery rate may yield different findings.

The impact of birth anesthesia on the parameters of oxygenation and acid–base balance in umbilical cord blood

2019 ◽  
Vol 33 (20) ◽  
pp. 3445-3452 ◽  
Author(s):  
Paweł Szymanowski ◽  
Wioletta Katarzyna Szepieniec ◽  
Marcin Zarawski ◽  
Paweł Gruszecki ◽  
Hanna Szweda ◽  
...  
Keyword(s):  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance ◽  
The Impact

Umbilical cord blood acid-base balance and gas composition in relation to the use of epidural analgesia in vaginal delivery

2019 ◽  
Vol 5_2019 ◽  
pp. 70-76
Author(s):  
Tysyachnyy O.V. Tysyachnyy ◽  
Baev O.R. Baev ◽  
Evgrafova A.V. Evgrafova ◽  
Prikhodko A.M. Prikhodko ◽  
Pismensky S.V. Pismensky S ◽  
...  
Keyword(s):  
Epidural Analgesia ◽  
Cord Blood ◽  
Vaginal Delivery ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Gas Composition ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

scholarly journals Effect of the umbilical cord blood acid-base status and gas values on the yield of mononuclear cells and CD34+ cells

2012 ◽  
Vol 38 (7) ◽  
pp. 997-1003 ◽  
Author(s):  
Satoko Ebina ◽  
Atsuko Omori ◽  
Ayako Tarakida ◽  
Tomoka Ogasawara ◽  
Mami Manabe ◽  
...  
Keyword(s):  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Mononuclear Cells ◽  
Acid Base ◽  
Cd34 Cells ◽  
Acid Base Status

scholarly journals Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Bo Y. Park ◽  
Brian K. Lee ◽  
Igor Burstyn ◽  
Loni P. Tabb ◽  
Jeff A. Keelan ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Androgen Levels

scholarly journals Optimization of Hypoxic Brain Injuries Diagnostics in Full-Term Newborns

2021 ◽  
Vol 6 (2) ◽  
pp. 133-141
Author(s):  
M. S. Panova ◽  
A. S. Panchenko ◽  
V. A. Mudrov
Keyword(s):  
Cord Blood ◽  
Brain Damage ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Full Term ◽  
Damage Diagnosis ◽  
Hypoxic Brain Damage ◽  
Hypoxic Brain ◽  
Tnf Α ◽  
Term Newborns

The problem of early diagnosis of the central nervous system damage in newborn before the onset of clinical symptoms remains relevant at the present time.The aim of the study was to optimize the hypoxic brain damage diagnosis in full-term newborns by analyzing the concentration of cytokines in the umbilical cord blood.Materials and methods. During the first stage of the study, a prospective analysis of concentrations of interleukins (IL-1β, IL-4, IL-6, IL-8, IL-10), TNF-α and neuron-specific enolase (NSE) in the umbilical cord blood serum of full-term newborns was performed. The second stage of the study included the retrospective analysis of clinical data and instrumental research methods. The main method for diagnosing in the development of hypoxic brain damage in newborns was neurosonography.Results. The development of hypoxic brain damage is evidenced by the concentration of IL-1β over 30.3 pg/ml, IL-4 – over 1.7 pg/ml, IL-6 – over 79.4 pg/ml, IL-8 – over 107.7 pg/ml, NSE – more than 10.3 ng/ml and TNF-α – more than 1.6 pg/ml in umbilical cord blood.Conclusion. The results of the study confirmed that the comprehensive assessment of the cytokines concentration in the umbilical cord blood improves the hypoxic brain damage diagnosis in newborns. Analysis of the level of these markers immediately after the birth will optimize the management tactics of newborns who have undergone hypoxic exposure in antenatal and intranatal period. 

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