scholarly journals Incidence and risk factors of retinopathy of prematurity in an Italian cohort of preterm infants

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Carlo Dani ◽  
Caterina Coviello ◽  
Fiorenza Panin ◽  
Saverio Frosini ◽  
Simonetta Costa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Infants ◽  
Retinopathy Of Prematurity ◽  
Neonatal Intensive Care ◽  
Neonatal Intensive Care Units ◽  
Maternal Milk ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Stage 1 ◽  
Mother’S Own Milk

AbstractObjectiveNon-negligible differences in retinopathy of prematurity (ROP) and its risk factors between different neonatal intensive care units (NICUs) are reported. Our aim was to assess the incidence and risk factors for ROP development in a large cohort of very preterm infants who were assisted in two Italian NICUs.MethodsPreterm infants with gestational age between 23+ 0and 29+ 6weeks were stratified into subgroups of infants who developed ROP and those who did not; their clinical characteristics were compared with univariate and multivariable logistic regression analyses.ResultsWe studied a total of 178 infants of whom 67 (38%) developed ROP (stage 1:n = 12; stage 2:n = 41; stage 3:n = 14). Regression analysis demonstrated that maternal milk (OR 0.979, 95% Cl 0.961–0.998) decreased the risk of developing ROP, while intraventricular hemorrhage (IVH) (OR 2.055, 95% Cl 1.120–3.772) increased it. Moreover, maternal milk was found to decrease (OR 0.981, 95% Cl 0.964–0.997) the risk of ROP at discharge, while RBC transfusion increased it (OR 1.522, 95% Cl 1.208–1.916).ConclusionsIn our cohort the occurrence of ROP was similar to that previously reported. Strategies for promoting the use of mother’s own milk, preventing IVH, and standardizing the approach to RBC transfusions could contribute to decreasing the risk of ROP in very preterm infants.

Association of Resident Duty Hour Reform and Neonatal Outcomes of Very Preterm Infants

2017 ◽  
Vol 34 (14) ◽  
pp. 1396-1404
Author(s):  
Bruno Piedboeuf ◽  
Robert Platt ◽  
Keith Barrington ◽  
Victoria Bizgu ◽  
Prakesh Shah ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Neonatal Intensive Care ◽  
Neonatal Outcomes ◽  
Neonatal Intensive Care Units ◽  
Composite Outcome ◽  
Major Morbidity ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Before And After ◽  
Resident Duty

Objective To assess the association of the 2011 Quebec provincial resident duty hour reform, which reduced the maximum consecutive hours worked by all residents from 24 to 16 hours, with neonatal outcomes. Study Design Retrospective observational study of 4,271 infants born between 23 and 32 weeks, admitted at five Quebec neonatal intensive care units (NICUs) participating in the Canadian Neonatal Network (CNN) between 2008 and 2015 was conducted. Adjusted odds ratios (AORs) were calculated to compare mortality and the composite outcome of mortality or major morbidity before and after the implementation of the duty hour reform. Results The mortality rate was 8.4% (218/2,598) before the resident duty hour reform and 8.6% (182/2,123) after the reform (odds ratio [OR] = 1.02, 95% confidence interval [CI] = 0.83–1.26). The composite outcome rate was 32% (830/2,598) before the duty hour reform and 29% (615/2,123) after the reform (OR = 0.87, 95% CI = 0.77–0.98). In the adjusted analyses, the resident call-hour reform was not associated with a significant change in mortality (AOR = 1.17, 95% CI = 0.91–1.50) or composite outcome (AOR = 0.87, 95% CI = 0.74–1.03). Conclusion Reducing residents' duty hours from 24 to 16 hours in Quebec was not associated with a difference in mortality or the composite outcome of very preterm infants.

Prenatal Risk Factors for Severe Retinopathy of Prematurity Among Very Preterm Infants of the Australian and New Zealand Neonatal Network

PEDIATRICS ◽  
2005 ◽  
Vol 115 (4) ◽  
pp. 990-996 ◽  
Author(s):  
B. A. Darlow ◽  
J. L. Hutchinson ◽  
D. J. Henderson-Smart ◽  
D. A. Donoghue ◽  
J. M. Simpson ◽  
...  
Keyword(s):  
Risk Factors ◽  
New Zealand ◽  
Preterm Infants ◽  
Retinopathy Of Prematurity ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Prenatal Risk ◽  
Prenatal Risk Factors

scholarly journals Variations in length of stay among survived very preterm infants admitted to Chinese neonatal intensive care units

2022 ◽  
Author(s):  
Min Zhang ◽  
Yan-Chen Wang ◽  
Jin-Xing Feng ◽  
Ai-Zhen Yu ◽  
Jing-Wei Huang ◽  
...  
Keyword(s):  
Intensive Care ◽  
Length Of Stay ◽  
Intensive Care Units ◽  
Preterm Infants ◽  
Gestational Age ◽  
Neonatal Intensive Care ◽  
Neonatal Intensive Care Units ◽  
Multicenter Cohort Study ◽  
Very Preterm Infants ◽  
Very Preterm

Abstract Background This study aimed to describe length of stay (LOS) to discharge and site variations among very preterm infants (VPIs) admitted to 57 Chinese neonatal intensive care units (NICUs) and to investigate factors associated with LOS for VPIs. Methods This retrospective multicenter cohort study enrolled all infants < 32 weeks’ gestation and admitted to 57 NICUs which had participated in the Chinese Neonatal Network, within 7 days after birth in 2019. Exclusion criteria included major congenital anomalies, NICU deaths, discharge against medical advice, transfer to non-participating hospitals, and missing discharge date. Two multivariable linear models were used to estimate the association of infant characteristics and LOS. Results A total of 6580 infants were included in our study. The overall median LOS was 46 days [interquartile range (IQR): 35–60], and the median corrected gestational age at discharge was 36 weeks (IQR: 35–38). LOS and corrected gestational age at discharge increased with decreasing gestational age. The median corrected gestational age at discharge for infants at 24 weeks, 25 weeks, 26 weeks, 27–28 weeks, and 29–31 weeks were 41 weeks, 39 weeks, 38 weeks, 37 weeks and 36 weeks, respectively. Significant site variation of LOS was identified with observed median LOS from 33 to 71 days in different hospitals. Conclusions The study provided concurrent estimates of LOS for VPIs which survived in Chinese NICUs that could be used as references for medical staff and parents. Large variation of LOS independent of infant characteristics existed, indicating variation of care practices requiring further investigation and quality improvement.

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