scholarly journals Mitral valve velocity time integral and passive leg raise as a measure of volume responsiveness

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Ralphe Bou Chebl ◽  
Gilbert Abou Dagher ◽  
Jeffrey Wuhantu ◽  
Rana Bachir ◽  
Jennifer Carnell
2021 ◽  
Vol 8 ◽  
Author(s):  
Ryohei Suzuki ◽  
Yunosuke Yuchi ◽  
Haruka Kanno ◽  
Takahiro Saito ◽  
Takahiro Teshima ◽  
...  

Post-capillary pulmonary hypertension (PH) is a life-threatening complication in dogs with myxomatous mitral valve disease (MMVD). An increase in pulmonary vascular resistance (PVR) is associated with post-capillary PH progression. In humans, PVR estimated by echocardiography (PVRecho) enables the non-invasive assessment of PVR in patients with PH. This study aimed to evaluate the clinical utility of PVRecho in dogs with MMVD, PH probability, and right-sided congestive heart failure (R-CHF). Dogs with MMVD and detectable tricuspid valve regurgitation were included in the study. Dogs were classified into three PH probability groups (low/intermediate/high) and according to the presence or absence of R-CHF. All dogs underwent echocardiographic measurements for right ventricular (RV) morphology and function. PVRecho was calculated by two methods using tricuspid valve regurgitation velocity and velocity–time integral of the pulmonary artery flow (PVRecho and PVRecho2). RV size indicators were significantly higher with a higher probability of PH. RV strain and velocity–time integral of the pulmonary artery flow in the high probability group were significantly lower than those in the other groups. Tricuspid valve regurgitation velocity, PVRecho, and PVRecho2 were significantly higher with an increase in PH probability. Logistic regression analysis revealed a significant association between the presence of R-CHF and increased PVRecho2 and end-diastolic RV internal dimension normalized by body weight. PVRecho and PVRecho2 showed significant differences among the PH probability groups. These non-invasive variables may be useful for the diagnosis and stratification of PH and the determination of the presence of R-CHF in dogs with MMVD.


2020 ◽  
Vol 48 (5) ◽  
pp. 504-508
Author(s):  
Ya Tan ◽  
Shi Zeng ◽  
YuShan Liu ◽  
HuaYu Tang ◽  
BaiHua Zhao

AbstractObjectiveTo observe Doppler ultrasound changes in the two segments of the posterior cerebral artery (PCA) in fetuses with transposition of the great arteries (TGA).MethodsThe peak systolic velocity (PSV), end-diastolic velocity (EDV), pulsatility index (PI), and velocity-time integral (VTI) of the two segments of PCA (the first segment: PCAS1, the second segment: PCAS2) and of the middle cerebral artery (MCA) were compared in TGA fetuses and normal fetuses. The abnormality rate between the PCAS1-PI and MCA-PI was compared in TGA fetuses.ResultsThe PCAS1-PI and MCA-PI were smaller in the TGA fetuses than in the controls (all P < 0.05), but the PCAS2-PI was unchanged (P > 0.05). The MCA-VTI, PCAS1-VTI, and PCAS2-VTI were larger in the TGA fetuses (all P < 0.05). In the TGA fetuses, the abnormality rate of the PCAS1-PI was significantly higher than that of the MCA-PI (P < 0.05).ConclusionIn fetuses with TGA, there were hemodynamic differences between the two segments of the posterior cerebral arteries. Moreover, PCAS1 exhibited signs of vasodilatation more obviously than did the MCA in fetuses with TGA.


2019 ◽  
Vol 55 (5) ◽  
pp. 823-828
Author(s):  
Shuichi Shiraishi ◽  
Keiko Bamba ◽  
Ai Sugimoto ◽  
Masashi Takahashi ◽  
Masanori Tsuchida

2011 ◽  
Vol 57 (14) ◽  
pp. E802
Author(s):  
Punam A. Pabari ◽  
Andreas Kyriacou ◽  
Michela Moraldo ◽  
Alun D. Hughes ◽  
Jamil Mayet ◽  
...  

Heart ◽  
2017 ◽  
Vol 103 (Suppl 5) ◽  
pp. A93-A93
Author(s):  
Graham Cole ◽  
Stefania Sacchi ◽  
Niti Dhutia ◽  
Matthew Shun-Shin ◽  
Massoud Zolgharni ◽  
...  

2021 ◽  
Vol 2 (Supplement_1) ◽  
pp. A3-A4
Author(s):  
P Vokolos ◽  
D Kennedy ◽  
K Lushington ◽  
J Martin ◽  
D Wabnitz ◽  
...  

Abstract Children with sleep disordered breathing (SDB) have evidence of increased blood flow velocity and sympathetic overactivity. Sympathetic overactivity leads to peripheral vasoconstriction, increased vascular resistance and consequently, increases blood flow velocity. Early vascular ageing involves premature arterial thickening and stiffening that leads to changes in vascular function. Both increased blood flow velocity and sympathetic overactivity are promoters of arterial remodelling and hence, early vascular ageing. No studies have directly histologically investigated arterial wall structure in children with SDB and how it relates to vascular function. Thirty-six children scheduled for tonsillectomy underwent polysomnography to determine SDB severity and resting brachial artery blood flow velocity (velocity time integral and peak systolic velocity) using Doppler ultrasound. The dorsal lingual artery (tonsil) was stained using hematoxylin and eosin techniques to examine arterial wall structures. Increased velocity time integral correlated with increased arterial medial thickness (r = 0.50, P&lt;0.01), arterial smooth muscle cells (r =0.43, P&lt;0.05) and arterial smooth muscle layers (r=0.45, P&lt;0.01). These relationships remained significant after controlling for body-mass index (BMI). Increased BMI was associated with increased velocity time integral (r=0.61, P&lt;0.01), arterial medial thickness (r=0.37, P&lt;0.05) and arterial medial area (r=0.36, P&lt;0.05). SpO2nadir (TST/REM) was inversely associated with arterial medial area (r=-0.35; r=-0.38, P&lt;0.05). These results demonstrate that increased blood flow velocity is associated with changes in arterial wall composition in children with SDB. This suggests that paediatric SDB, a treatable disorder, is potentially a modifiable risk factor for early vascular ageing and resultant cardiovascular disease in adulthood.


Author(s):  
Deepti Bodh ◽  
Mozammel Hoque ◽  
Abhishek Chandra Saxena

Background: Pulsed-wave Doppler measures blood flow at specific point and provides information on velocity, direction and uniformity of blood flow throughout cardiac cycle. Till date, there is no published data on study of cardiac parameters using pulsed-wave Doppler echocardiography in Indian Spitz dogs.Methods: Twenty-four clinically normal Indian Spitz dogs were subjected to pulsed-wave Doppler echocardiography to determine the reference intervals for Doppler parameters of blood flow through mitral, tricuspid and aortic valves. Mitral peak E and A-wave velocities, E/A ratio, deceleration time, isovolumic relaxation time, E and A-wave velocity time integral, E duration and A duration were 0.69±0.09 m/s, 0.43±0.12 m/s, 1.69±0.45, 111.25±35.94 ms, 48.50±24.77 ms, 0.07±0.01 m and 0.04±0.02 m, 196.88±44.38 ms and 181.25±64.89 ms, respectively. Tricuspid peak E and A-wave velocities, E/A ratio and E and A-wave velocity time integral were 0.57±0.11 m/s, 0.38±0.08 m/s, 1.56±0.32 and 0.07±0.02 m and 0.05±0.01 m, respectively. Aortic peak velocity, velocity time integral and ejection time were 0.87±0.07 m/s, 0.11±0.02 m and 0.25±0.04 s, respectively. Conclusion: The reference values of flow parameters across mitral, tricuspid and aortic valves using pulsed-wave Doppler echocardiography were determined. Mitral, tricuspid and aortic valve flow variables were unaffected by gender whereas isovolumic relaxation correlated positively with body weight.


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