scholarly journals The role of point-of-care ultrasound in the diagnosis and management of necrotizing soft tissue infections

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Luís Magalhães ◽  
Sara Raquel Pereira Martins ◽  
Ramon Nogué
POCUS Journal ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 13-14
Author(s):  
Hadiel Kaiyasah, MD, MRCS (Glasgow), ABHS-GS ◽  
Maryam Al Ali, MBBS

Soft tissue ultrasound (ST-USS) has been shown to be of utmost importance in assessing patients with soft tissue infections in the emergency department or critical care unit. It aids in guiding the management of soft tissue infection based on the sonographic findings.


2020 ◽  
Vol 113 (12) ◽  
pp. 645-650
Author(s):  
Nipam Shah ◽  
Jonathan Buice ◽  
Ashlyn Shields ◽  
Christopher Pruitt

Toxins ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 332 ◽  
Author(s):  
Patience Shumba ◽  
Srikanth Mairpady Shambat ◽  
Nikolai Siemens

Necrotizing soft tissue infections (NSTIs) are critical clinical conditions characterized by extensive necrosis of any layer of the soft tissue and systemic toxicity. Group A streptococci (GAS) and Staphylococcus aureus are two major pathogens associated with monomicrobial NSTIs. In the tissue environment, both Gram-positive bacteria secrete a variety of molecules, including pore-forming exotoxins, superantigens, and proteases with cytolytic and immunomodulatory functions. The present review summarizes the current knowledge about streptococcal and staphylococcal toxins in NSTIs with a special focus on their contribution to disease progression, tissue pathology, and immune evasion strategies.


2017 ◽  
Vol 42 (1) ◽  
pp. 82-87 ◽  
Author(s):  
Myriam Martinez ◽  
Thomas Peponis ◽  
Aglaia Hage ◽  
Daniel D. Yeh ◽  
Haytham M. A. Kaafarani ◽  
...  

2016 ◽  
Vol 23 (11) ◽  
pp. 1298-1306 ◽  
Author(s):  
Sathyaseelan Subramaniam ◽  
Jacqueline Bober ◽  
Jennifer Chao ◽  
Shahriar Zehtabchi

2021 ◽  
Author(s):  
Jiangfeng Wu ◽  
Lijing Ge ◽  
Xiaoyun Wang ◽  
Yun Jin

Aims: To evaluate the effect of point-of-care ultrasound (POCUS) for the diagnosis of an abscess and to compare the diagnostic accuracy of POCUS and physical examination (PE) in paediatric patients with skin and soft tissue infections (SSTI) in the emergency department.Material and methods: A comprehensive literature search was carried out to identify Englishlanguage studies on POCUS for differentiating an abscess from cellulitis in paediatric patients with SSTI. The quality of the study was assessed by the Quality Assessment of Diagnostic Accuracy Studies 2 tool, and pooled sensitivity and specificity of various POCUS findings were determined.Results: Seven studies with a total of 870 patients were included. There was significant heterogeneity across the included studies. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio for the diagnosis of abscess by POCUS were 0.90 (95% confidence interval [CI], 0.82-0.95), 0.80 (95% CI, 0.72-0.86), 4.5 (95% CI, 3.1-6.4), 0.13 (95% CI, 0.07-0.23), and 36 (95% CI, 17-75), respectively, with an area under the curve (AUC) was 0.89 (95% CI, 0.86-0.91). Four studies provided data regarding the PE method. The pooled sensitivity, specificity, and AUC of PE for the abscess were 0.84 (95% CI, 0.80-0.88), 0.69 (95% CI, 0.62-0.76), and 0.85 (95% CI, 0.81-0.88).Conclusions: POCUS is useful in identifying abscesses in paediatric patients with SSTI in emergency department, especially when PE is equivocal and outperforms PE alone.


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