scholarly journals Global, regional, and national prevalence of diabetes mellitus in patients with pulmonary tuberculosis: a systematic review and meta-analysis

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Minmin Li ◽  
Tao Chen ◽  
Zhongqiu Hua ◽  
Hong Yan ◽  
Duolao Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Pulmonary Tuberculosis ◽  
Meta Analysis ◽  
Eastern Mediterranean Region ◽  
Marshall Islands ◽  
Primary Data ◽  
Bibliographic Databases ◽  
Original Research ◽  
National Prevalence ◽  
Prevalence Of Diabetes Mellitus

Abstract Background Both pulmonary tuberculosis (PTB) and diabetes mellitus (DM) are major global public health problems. We estimated the global, regional, and national prevalence of diabetes mellitus in a population with PTB. Methods We searched for observational studies of DM in people with PTB using the PubMed and Embase electronic bibliographic databases, focusing on articles published in the English language from database inception until March 31, 2021. We included original research that reported the prevalence of DM in PTB or those that had sufficient data to compute these estimates. Studies were excluded if they did not provide primary data or were case studies or reviews. Two authors independently extracted the articles and collected detailed information using a predefined questionnaire. A country-specific random-effects meta-analysis was used for countries with two or more available studies, and a fractional response regression model was employed to predict the prevalence of DM in PTB for countries with one or no study. The study was registered with the International Prospective Register of Systematic Reviews, using the registration number CRD42018101989. Results We identified 22,658 studies, and 153, across 51 countries, were retained for data extraction. The global prevalence of DM among patients with PTB was estimated to be 13.73% (95% confidence interval [CI] 12.51–14.95). The prevalence rates were 19.32% (95% CI 13.18–25.46) in the region of the Americas, 17.31% (95% CI 12.48–22.14) in the European region, 14.62% (95% CI 12.05–17.18) in Southeast Asia, 13.59% (95% CI 7.24–19.95) in the western Pacific region, 9.61% (95% CI 4.55–14.68) in the eastern Mediterranean region, and 9.30% (95% CI 2.83–15.76) in the African region. The country with the highest estimated prevalence was the Marshall Islands (50.12%; 95% CI 4.28–95.76). Conclusion Comorbid PTB and DM remain prevalent worldwide.

scholarly journals Global, regional, and national prevalence of diabetes mellitus in patients with pulmonary tuberculosis: a systematic review and meta-analysis

2020 ◽  
Author(s):  
Minmin Li ◽  
Tao Chen ◽  
Zhongqiu Hua ◽  
Hong Yan ◽  
Duolao Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Pulmonary Tuberculosis ◽  
Eastern Mediterranean ◽  
Eastern Mediterranean Region ◽  
Public Health Problem ◽  
Primary Data ◽  
Bibliographic Databases ◽  
Original Research ◽  
National Prevalence ◽  
Prevalence Of Diabetes Mellitus

Abstract Background：Both TB and DM are major global public health problem. We estimated the global, regional, and national prevalence of diabetes mellitus in population with pulmonary tuberculosis.Methods：We assessed observational studies of diabetes mellitus in people with pulmonary tuberculosis, using PubMed and Embase electronic bibliographic databases in English language, to identify articles published until August 31, 2018. We included original research that reported the prevalence of diabetes mellitus in pulmonary tuberculosis or had enough data to compute these estimates. Studies were excluded if they did not provide primary data or were case studies and reviews. 2 authors independent extraction of articles and collected detailed information using predefined questionnaire. The country-specific random-effects meta-analyses for countries with two or more available studies and a fractional response regression model to predict individual studies prevalence of diabetes mellitus in pulmonary tuberculosis for countries with one or no study. The study is registered with PROSPERO, registration number CRD42018101989.Results. We identified 18042 studies, and 127 were retained for data extraction across 46 countries. The global prevalence of diabetes mellitus in patients with pulmonary tuberculosis were estimated to be 12.07% (95%CI: 10.43-14.85). The prevalence was 13.38% (95%CI: 11.16-16.05) in region of Americas, 13.34% (95%CI: 12.82-14.61) in European region, 12.68% (95%CI: 9.15-16.37) in South-East Asia, 12.56% (95%CI: 11.79-22.70) in Western Pacific region, 10.95% (95%CI: 9.04-17.83) in Eastern Mediterranean region and 7.54% (95%CI: 6.51-8.77) in African region. The country with the highest estimated prevalence was Mauritius (39.65%, 95%CI: 4.22-90.74).Conclusion: Pulmonary tuberculosis combined diabetes mellitus is still prevalent.

scholarly journals Global, regional, and national prevalence of diabetes mellitus in patients with pulmonary tuberculosis: a systematic review and meta-analysis

2019 ◽  
Author(s):  
Minmin Li ◽  
Tao Chen ◽  
Zhongqiu Hua ◽  
Ni Zhu ◽  
Duolao Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Pulmonary Tuberculosis ◽  
Health Care Providers ◽  
Meta Analysis ◽  
Eastern Mediterranean Region ◽  
Original Research ◽  
Care Providers ◽  
National Prevalence ◽  
Prevalence Of Diabetes Mellitus

Abstract Background. The concept that people with pulmonary tuberculosis are at risk of developing diabetes mellitus has been raised. However, the prevalence of diabetes mellitus in patients with pulmonary tuberculosis have not been well established. We aim to estimate the global, regional, and national prevalence of diabetes mellitus in population with pulmonary tuberculosis. Methods. In this systematic review and meta-analysis, we assessed observational studies of diabetes mellitus in people with pulmonary tuberculosis, using PubMed and Embase electronic bibliographic databases in English language, to identify articles published until August 31, 2018. We included original research studies published in a peer-reviewed journal and reported the prevalence of diabetes mellitus or had enough data to compute these estimates. Studies were excluded if they did not provide primary data or were case studies and reviews. Independent extraction of articles and collected detailed information by 2 authors using predefined questionnaire, including study quality indicators. The country-specific random-effects meta-analyses for countries with two or more available studies and a fractional response regression model to predict individual studies prevalence of diabetes mellitus in patients with pulmonary tuberculosis for countries with one or no study. The study is registered with PROSPERO, registration number CRD42018101989. Results. We identified 18042 studies, and 127 were retained for data extraction across 46 countries. The global prevalence of diabetes mellitus in patients with pulmonary tuberculosis were estimated to be 12.07% (95%CI: 10.43-14.85). The prevalence of diabetes mellitus in patients with pulmonary tuberculosis was 13.38% (95%CI: 11.16-16.05) in region of Americas, 13.34% (95%CI: 12.82-14.61) in European region, 12.68% (95%CI: 9.15-16.37) in South-East Asia, 12.56% (95%CI: 11.79-22.70) in Western Pacific region, 10.95% (95%CI: 9.04-17.83) in Eastern Mediterranean region and 7.54% (95%CI: 6.51-8.77)in African region. The country with the highest estimated prevalence of pulmonary tuberculosis combined diabetes mellitus were Mauritius (39.65%, 95%CI: 4.22-90.74). Conclusion. Our findings suggest that pulmonary tuberculosis combined diabetes mellitus is still prevalent. As such, diabetes mellitus deserves more attention from PTB health-care providers, researchers, policy makers, and stakeholders for improved detection, overall proper management, and efficient control of diabetes mellitus in people with pulmonary tuberculosis.

scholarly journals Prevalence of Diabetes Mellitus and Its Associated Unfavorable Outcomes in Patients With Acute Respiratory Syndromes Due to Coronaviruses Infection: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 13 ◽  
pp. 117955142096249
Author(s):  
Isabel Pinedo-Torres ◽  
Magaly Flores-Fernández ◽  
Marlon Yovera-Aldana ◽  
Claudia Gutierrez-Ortiz ◽  
Paolo Zegarra-Lizana ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Health Outcomes ◽  
Meta Analysis ◽  
Population Based ◽  
Pooled Analysis ◽  
Sensitivity Analyses ◽  
Cross Sectional ◽  
Treatment Regimens ◽  
Prevalence Of Diabetes Mellitus

Introduction: Only 3 types of coronavirus cause aggressive respiratory disease in humans (MERS-Cov, SARS-Cov-1, and SARS-Cov-2). It has been reported higher infection rates and severe manifestations (ICU admission, need for mechanical ventilation, and death) in patients with comorbidities such as diabetes mellitus (DM). For this reason, this study aimed to determine the prevalence of diabetes comorbidity and its associated unfavorable health outcomes in patients with acute respiratory syndromes for coronavirus disease according to virus types. Methods: Systematic review of literature in Pubmed/Medline, Scopus, Web of Science, Cochrane, and Scielo until April of 2020. We included cohort and cross-sectional studies with no restriction by language or geographical zone. The selection and extraction were undertaken by 2 reviewers, independently. The study quality was evaluated with Loney’s instrument and data were synthesized by random effects model meta-analysis. The heterogeneity was quantified using an I2 statistic. Funnel plot, Egger, and Begg tests were used to evaluate publication biases, and subgroups and sensitivity analyses were performed. Finally, we used the GRADE approach to assess the evidence certainty (PROSPERO: CRD42020178049). Results: We conducted the pooled analysis of 28 studies (n = 5960). The prevalence analysis according to virus type were 451.9 diabetes cases per 1000 infected patients (95% CI: 356.74-548.78; I2 = 89.71%) in MERS-Cov; 90.38 per 1000 (95% CI: 67.17-118.38) in SARS-Cov-1; and 100.42 per 1000 (95% CI: 77.85, 125.26 I2 = 67.94%) in SARS-Cov-2. The mortality rate were 36%, 6%, 10% and for MERS-Cov, SARS-Cov-1, and SARS-Cov-2, respectively. Due to the high risk of bias (75% of studies had very low quality), high heterogeneity ( I2 higher than 60%), and publication bias (for MERS-Cov studies), we down rate the certainty to very low. Conclusion: The prevalence of DM in patients with acute respiratory syndrome due to coronaviruses is high, predominantly with MERS-Cov infection. The unfavorable health outcomes are frequent in this subset of patients. Well-powered and population-based studies are needed, including detailed DM clinical profile (such as glycemic control, DM complications, and treatment regimens), comorbidities, and SARS-Cov-2 evolution to reevaluate the worldwide prevalence of this comorbidity and to typify clinical phenotypes with differential risk within the subpopulation of DM patients.

scholarly journals Prevalence of gestational diabetes mellitus in Eastern Mediterranean region: a systematic review and meta-analysis

Endocrine ◽  
2019 ◽  
Vol 65 (3) ◽  
pp. 505-514 ◽  
Author(s):  
Mahin Badakhsh ◽  
Fereshteh Daneshi ◽  
Mahnaz Abavisani ◽  
Hosien Rafiemanesh ◽  
Salehoddin Bouya ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Mediterranean Region ◽  
Eastern Mediterranean ◽  
Meta Analysis ◽  
Eastern Mediterranean Region

scholarly journals Global prevalence of diabetes mellitus in patients with tuberculosis: a systematic review and meta-analysis protocol

BMJ Open ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. e015170 ◽  
Author(s):  
Aurel T Tankeu ◽  
Jean Joël Bigna ◽  
Jobert Richie Nansseu ◽  
Francky Teddy A Endomba ◽  
Guy Sadeu Wafeu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Meta Analysis ◽  
Global Prevalence ◽  
Prevalence Of Diabetes Mellitus ◽  
Analysis Protocol

Sex Differences in Osteomyelitis of the Foot in Persons With Diabetes Mellitus: A Meta-Analysis

2021 ◽  
Vol 67 (5) ◽  
pp. 19-25
Author(s):  
Le-Xuan Zhang ◽  
Yu-Ting Wang ◽  
Jun Zhao ◽  
Yang Li ◽  
Hong-lin Chen
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Meta Analysis ◽  
Included Study ◽  
Original Research ◽  
China National Knowledge Infrastructure ◽  
Foot Complications ◽  
Newcastle Ottawa Scale ◽  
Diabetic Foot Disease ◽  
Foot Disease

BACKGROUND: Osteomyelitis of the foot is a risk factor for amputation in persons with diabetes mellitus. There is some evidence to suggest that patient sex affects the risk of diabetes-related foot complications. PURPOSE: To examine the effect of sex on osteomyelitis risk in patients with diabetic foot disease. METHODS: Systematic searches of PubMed and the China National Knowledge Infrastructure were performed from inception through May 2020 using the terms “diabetic foot” and “osteomyelitis.” Original research studies including persons with diabetes mellitus, diabetic foot disease, or ulcers as well as reports of osteomyelitis were included. Study quality was assessed according to the Newcastle–Ottawa Scale. The pooled odds ratio (OR) and 95% confidence interval (CI) for osteomyelitis were calculated by sex. RESULTS: Nine (9) studies from 6 countries involving 2583 patients met the inclusion criteria for analysis. No significant publication bias was observed. The average age of patients was 65.2 years, and 32.03% of men and 30.0% of women were diagnosed with osteomyelitis. The pooled OR was 1.14 (95% CI, 0.94-1.38; P = .76). Regression analysis (t = -0.61; P > .561) showed no association between the incidence of osteomyelitis and ORs. CONCLUSION: This meta-analysis suggests that patient sex does not affect the odds of having osteomyelitis among persons with diabetes and diabetic foot disease or ulcers.

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