scholarly journals Global, regional, and national prevalence of diabetes mellitus in patients with pulmonary tuberculosis: a systematic review and meta-analysis

Author(s):  
Minmin Li ◽  
Tao Chen ◽  
Zhongqiu Hua ◽  
Hong Yan ◽  
Duolao Wang ◽  
...  

Abstract Background:Both TB and DM are major global public health problem. We estimated the global, regional, and national prevalence of diabetes mellitus in population with pulmonary tuberculosis.Methods:We assessed observational studies of diabetes mellitus in people with pulmonary tuberculosis, using PubMed and Embase electronic bibliographic databases in English language, to identify articles published until August 31, 2018. We included original research that reported the prevalence of diabetes mellitus in pulmonary tuberculosis or had enough data to compute these estimates. Studies were excluded if they did not provide primary data or were case studies and reviews. 2 authors independent extraction of articles and collected detailed information using predefined questionnaire. The country-specific random-effects meta-analyses for countries with two or more available studies and a fractional response regression model to predict individual studies prevalence of diabetes mellitus in pulmonary tuberculosis for countries with one or no study. The study is registered with PROSPERO, registration number CRD42018101989.Results. We identified 18042 studies, and 127 were retained for data extraction across 46 countries. The global prevalence of diabetes mellitus in patients with pulmonary tuberculosis were estimated to be 12.07% (95%CI: 10.43-14.85). The prevalence was 13.38% (95%CI: 11.16-16.05) in region of Americas, 13.34% (95%CI: 12.82-14.61) in European region, 12.68% (95%CI: 9.15-16.37) in South-East Asia, 12.56% (95%CI: 11.79-22.70) in Western Pacific region, 10.95% (95%CI: 9.04-17.83) in Eastern Mediterranean region and 7.54% (95%CI: 6.51-8.77) in African region. The country with the highest estimated prevalence was Mauritius (39.65%, 95%CI: 4.22-90.74).Conclusion: Pulmonary tuberculosis combined diabetes mellitus is still prevalent.

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Minmin Li ◽  
Tao Chen ◽  
Zhongqiu Hua ◽  
Hong Yan ◽  
Duolao Wang ◽  
...  

Abstract Background Both pulmonary tuberculosis (PTB) and diabetes mellitus (DM) are major global public health problems. We estimated the global, regional, and national prevalence of diabetes mellitus in a population with PTB. Methods We searched for observational studies of DM in people with PTB using the PubMed and Embase electronic bibliographic databases, focusing on articles published in the English language from database inception until March 31, 2021. We included original research that reported the prevalence of DM in PTB or those that had sufficient data to compute these estimates. Studies were excluded if they did not provide primary data or were case studies or reviews. Two authors independently extracted the articles and collected detailed information using a predefined questionnaire. A country-specific random-effects meta-analysis was used for countries with two or more available studies, and a fractional response regression model was employed to predict the prevalence of DM in PTB for countries with one or no study. The study was registered with the International Prospective Register of Systematic Reviews, using the registration number CRD42018101989. Results We identified 22,658 studies, and 153, across 51 countries, were retained for data extraction. The global prevalence of DM among patients with PTB was estimated to be 13.73% (95% confidence interval [CI] 12.51–14.95). The prevalence rates were 19.32% (95% CI 13.18–25.46) in the region of the Americas, 17.31% (95% CI 12.48–22.14) in the European region, 14.62% (95% CI 12.05–17.18) in Southeast Asia, 13.59% (95% CI 7.24–19.95) in the western Pacific region, 9.61% (95% CI 4.55–14.68) in the eastern Mediterranean region, and 9.30% (95% CI 2.83–15.76) in the African region. The country with the highest estimated prevalence was the Marshall Islands (50.12%; 95% CI 4.28–95.76). Conclusion Comorbid PTB and DM remain prevalent worldwide.


2019 ◽  
Author(s):  
Minmin Li ◽  
Tao Chen ◽  
Zhongqiu Hua ◽  
Ni Zhu ◽  
Duolao Wang ◽  
...  

Abstract Background. The concept that people with pulmonary tuberculosis are at risk of developing diabetes mellitus has been raised. However, the prevalence of diabetes mellitus in patients with pulmonary tuberculosis have not been well established. We aim to estimate the global, regional, and national prevalence of diabetes mellitus in population with pulmonary tuberculosis. Methods. In this systematic review and meta-analysis, we assessed observational studies of diabetes mellitus in people with pulmonary tuberculosis, using PubMed and Embase electronic bibliographic databases in English language, to identify articles published until August 31, 2018. We included original research studies published in a peer-reviewed journal and reported the prevalence of diabetes mellitus or had enough data to compute these estimates. Studies were excluded if they did not provide primary data or were case studies and reviews. Independent extraction of articles and collected detailed information by 2 authors using predefined questionnaire, including study quality indicators. The country-specific random-effects meta-analyses for countries with two or more available studies and a fractional response regression model to predict individual studies prevalence of diabetes mellitus in patients with pulmonary tuberculosis for countries with one or no study. The study is registered with PROSPERO, registration number CRD42018101989. Results. We identified 18042 studies, and 127 were retained for data extraction across 46 countries. The global prevalence of diabetes mellitus in patients with pulmonary tuberculosis were estimated to be 12.07% (95%CI: 10.43-14.85). The prevalence of diabetes mellitus in patients with pulmonary tuberculosis was 13.38% (95%CI: 11.16-16.05) in region of Americas, 13.34% (95%CI: 12.82-14.61) in European region, 12.68% (95%CI: 9.15-16.37) in South-East Asia, 12.56% (95%CI: 11.79-22.70) in Western Pacific region, 10.95% (95%CI: 9.04-17.83) in Eastern Mediterranean region and 7.54% (95%CI: 6.51-8.77)in African region. The country with the highest estimated prevalence of pulmonary tuberculosis combined diabetes mellitus were Mauritius (39.65%, 95%CI: 4.22-90.74). Conclusion. Our findings suggest that pulmonary tuberculosis combined diabetes mellitus is still prevalent. As such, diabetes mellitus deserves more attention from PTB health-care providers, researchers, policy makers, and stakeholders for improved detection, overall proper management, and efficient control of diabetes mellitus in people with pulmonary tuberculosis.


2004 ◽  
Vol 10 (6) ◽  
pp. 754-760 ◽  
Author(s):  
K. Bagchi

Anaemia has remained a widespread public health problem in countries of the Eastern Mediterranean Region. Prevalence figures vary from a low of 17% to a high of over 70% among preschool children; from 14% to 42% among adolescents and from 11% to over 40% among women of childbearing age. Although the prevalence of anaemia has often been used as a proxy indicator for iron deficiency anaemia, this approach is not valid in settings where the etiology of anaemia is complex or unknown or where other micronutrient deficiencies of folate, vitamin B12 and vitamin A can co-exist. An integrated, multifactorial and multisectoral approach has to be adopted comprising targeted interventions to provide iron supplements to especially vulnerable segments of the population, in particular pregnant women; food-based approaches to increase iron intake through food fortification and dietary diversification; and other measures combined with iron interventions where other causes of anaemia are prevalent


Endocrine ◽  
2019 ◽  
Vol 65 (3) ◽  
pp. 505-514 ◽  
Author(s):  
Mahin Badakhsh ◽  
Fereshteh Daneshi ◽  
Mahnaz Abavisani ◽  
Hosien Rafiemanesh ◽  
Salehoddin Bouya ◽  
...  

Tubercle ◽  
1990 ◽  
Vol 71 (4) ◽  
pp. 271-276 ◽  
Author(s):  
F. Mugusi ◽  
A.B.M. Swai ◽  
K.G.M.M. Alberti ◽  
D.G. McLarty

2020 ◽  
Vol 13 (Supplement_1) ◽  
pp. S28-S32
Author(s):  
Reda M R Ramzy ◽  
Abdul Samid Al Kubati

Abstract Lymphatic filariasis (LF), a neglected tropical disease, is targeted for global elimination as a public health problem. This article reviews the history of LF control and elimination activities in the countries of the World Health Organization's (WHO) Eastern Mediterranean Region (EMR) over the last 2 decades. In 2000, the estimated at-risk population in EMR countries was 12.6 million people, accounting for approximately 1% of the global disease burden. Of the 22 EMR countries, 3 countries (Egypt, Sudan and Yemen) were LF endemic and the disease was suspected in 4 other countries (Djibouti, Oman, Somalia and Saudi Arabia). After almost 2 decades of implementing sustained control and prevention measures, Egypt and Yemen were successfully validated by the WHO as having achieved the elimination criteria in 2017 and 2019, respectively. In 2018, Sudan completed mapping of LF, reaching 26.2% geographical coverage where mass drug administration (MDA) is required and is scaling-up MDA. Extensive epidemiological assessment indicated the absence of LF transmission in the four suspected countries and no MDA required. Challenges faced during the elimination and post-elimination phases are described and discussed.


2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Shabrina Izzati ◽  
Masrul Basyar ◽  
Julizar Nazar

AbstrakTuberkulosis (TB) paru di wilayah kerja Puskesmas Andalas menduduki peringkat ke-2 kasus TB terbanyak di kota Padang.Belum banyak penelitian sebelumnya mengenai faktor risiko tuberkulosis paru di wilayah kerja Puskesmas Andalas. Penelitian ini bertujuan untuk melihat faktror risiko apa yang berhubungan dengan kejadian TB paru di wilayah kerja Puskesmas Andalas tahun 2013. Adapun faktor risiko yang diteliti yakni berupa status gizi, riwayat penyakit diabetes mellitus (DM), kondisi ventilasi rumah, kepadatan hunian rumah, dan pencahayaan rumah.Penelitian ini menggunakan desain case control.Sampel pada penelitian ini berjumlah 66, yakni terdiri dari 33 kasus (didapat dari rekam medis Puskesmas Andalas) dan 33 kontrol (sesuai kriteria inklusi kontrol).Data primer diperoleh dari wawancara dan pengukuran lansung. Hasil uji statistik dengan menggunakan uji chi square didapatkan faktor risiko yang berhubungan dengan kejadian TB paru adalah status gizi riwayat penyakit DM, kondisi ventilasi rumah, kepadatan hunian, dan pencahayaan rumah. Status gizi dan pencahayaan rumah secara statistic memiliki hubungan yang bermakna dengan kejadian TB paru, sedangkan riwayat penyakit DM, ventilasi dan kepadatan hunian secara statistik tidak memiliki hubungan yang bermakna dengan kejadian TB paru.Kata kunci: tuberkulosis paru, faktor risikoAbstractPulmonary Tuberculosis in Andalas Public Health Center was where the second largest number of TB cases found in 2012. There is not many study before about risk factors of pulmonary tuberculosis in the working area of Andalas Pulic Health Care. This study aims to know what are the risk factors of Pulmonary Tuberculosis in the working area of Andalas public health center in 2013. The risk factors were studied in this study are nutritional status, Diabetes mellitus, home ventilation, home occupancy density, and home lighting. This Study used a case control design. Samples in this study were 66 respondent consisting of 33 cases (obtained from medical record of Andalas public health center) and 33 controls (according to the inclusion criteria of controls). Primary data was got by interviews and direct measurement. The result of statistical test using chi square test can be concluded that risk factors that associated with pulmonary tuberculosis are nutritional status, diabetes mellitus, home ventilation, home occupancy density, and home lighting. Nutritional status and home lightting statistically are associated with pulmonary tuberculosis. In the other hand Diabetes mellitus history, home ventilation, and home occupancy density statistically are not associated with pulmonary tuberculosis.Keywords:pulmonary tuberculosis, risk factors


2002 ◽  
Vol 08 (06) ◽  
pp. 699-705
Author(s):  
L. Gillini ◽  
A. Seita

Tuberculosis [TB] is an important public health problem in the Eastern Mediterranean Region of the World Health Organization. Every year the disease kills 136, 000 people and affects 630, 000 more. HIV is the most significant risk factor for progression from subclinical infection with Mycobacterium tuberculosis to active TB. Although the HIV/AIDS threat in the Region appears to be relatively modest and so far there has been no evidence of an impact of HIV on TB epidemiology in the Region, there is a need to jointly address HIV infection and TB more effectively. In this paper the TB situation in the Region and the measures being taken to combat it are outlined. The impact of HIV infection on TB and the repercussions this could have on theTB situation in the Region are also discussed. Actions that are needed to tackle this double burden are suggested.


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