scholarly journals Prevalence of abnormal and borderline electrocardiogram changes in 13, 079 Chinese amateur marathon runners

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Xu Wen ◽  
Yu-min Huang ◽  
Tong-Hui Shen ◽  
Ying-Lan Gong ◽  
Rui-qing Dong ◽  
...  
Keyword(s):  
Sinus Bradycardia ◽  
Premature Ventricular Contraction ◽  
Left Ventricular ◽  
Ecg Changes ◽  
Sinus Arrhythmia ◽  
Marathon Runners ◽  
St Segment ◽  
Prolonged Qt Interval ◽  
Prolonged Qt ◽  
Ecg Abnormalities

Abstract Background The 12-lead electrocardiogram (ECG) has been adopted as an important component of preparticipation cardiovascular screening. However, there are still controversies in the screening and few studies with a large sample size have reported the results of ECGs of marathon runners. Therefore, the purpose of this study was to assess the prevalence of normal, borderline, and abnormal ECG changes in marathon runners. Methods The 12-lead ECG data of 13,079 amateur marathon runners between the ages of 18 and 35 years were included for analysis. The prevalence of ECG abnormalities among different gender groups was compared with chi-square tests. Results In terms of training-related changes, sinus bradycardia, sinus arrhythmia, and left ventricular high voltage were found in approximately 15, 5, and 3.28% of the participants, respectively. The incidence of right axis deviation in the marathon runners was 1.78%, which was slightly higher than the incidence of left axis deviation (0.88%). No more than 0.1% of the amateur marathon runners exhibited ST-segment depression, T wave inversion (TWI), premature ventricular contraction, pathologic Q waves, and prolonged QT interval. Conclusions Training-related ECG changes, including sinus bradycardia, sinus arrhythmia, and left ventricular high voltage, were common in amateur marathon runners. Most abnormal ECG changes, including ST-segment depression, TWI, premature ventricular contraction, pathologic Q waves, and prolonged QT interval, were infrequently found in amateur marathon runners. The data also suggested Chinese amateur marathon runners may have a relatively lower prevalence of ECG abnormalities than black and white runners.

scholarly journals Prevalence of Abnormal and Borderline Electrocardiogram Changes in 13, 079 Chinese Amateur Marathon Runners

2020 ◽  
Author(s):  
Xu Wen ◽  
Yumin Huang ◽  
Tonghui Shen ◽  
Yinglan Gong ◽  
Ruiqing Dong ◽  
...  
Keyword(s):  
Qt Interval ◽  
Sinus Bradycardia ◽  
Premature Ventricular Contraction ◽  
Left Ventricular ◽  
Ecg Changes ◽  
Sinus Arrhythmia ◽  
Marathon Runners ◽  
St Segment ◽  
Prolonged Qt Interval ◽  
Prolonged Qt

Abstract The purpose of this study was to assess the prevalence of normal, borderline and abnormal ECG changes in marathon runners. The 12-lead ECG data of 13,079 amateur marathon runners between the ages of 18 and 35 years were included for analysis. The prevalence of ECG abnormalities among different gender groups was compared with chi-square tests. In terms of training-related changes, sinus bradycardia, sinus arrhythmia and left ventricular high voltage were found in approximately 15%, 5% and 3.28% of the participants, respectively. The incidence of right axis deviation in the marathon runners was 1.78%, which was slightly higher than the incidence of left axis deviation (0.88%). No more than 0.1% of the amateur marathon runners exhibited ST segment depression, T wave inversion (TWI), premature ventricular contraction, pathologic Q waves and prolonged QT interval. In conclusion, training-related ECG changes, including sinus bradycardia, sinus arrhythmia and left ventricular high voltage, were common in the amateur marathon runners. Most of abnormal ECG changes, including ST segment depression, TWI, premature ventricular contraction, pathologic Q waves and prolonged QT interval, were infrequently found in the amateur marathon runners.

scholarly journals Electrocardiography in pre-participation screening and current guidelines for participation in competitive sports

2016 ◽  
Vol 144 (1-2) ◽  
pp. 104-110 ◽  
Author(s):  
Ljubica Georgijevic ◽  
Lana Andric
Keyword(s):  
Ventricular Tachycardia ◽  
Qt Interval ◽  
Sinus Bradycardia ◽  
Left Ventricular ◽  
Polymorphic Ventricular Tachycardia ◽  
Ecg Changes ◽  
Sinus Arrhythmia ◽  
Intraventricular Conduction ◽  
Wave Inversion ◽  
St Segment

Electrocardiography (ECG) is especially significant in pre-participation screening due to its ability to discover or to rise a suspicion for certain cardiovascular diseases and conditions that represent a serious health risk in athletes. Common, conditionally benign and training related ECG changes are sinus bradycardia and sinus arrhythmia, first degree atrioventricular block, incomplete right bundle branch block, benign early repolarization, and isolated QRS voltage criteria for left ventricular enlargement. Uncommon ECG changes, unrelated to training, and some specific syndromes are ST segment depression and/or ? 2mm T wave inversion in two or more adjacent leads, intraventricular conduction disorder, Wolf-Parkinson-White syndrome, long QT interval syndrome, short QT interval syndrome, catecholaminergic polymorphic ventricular tachycardia, monomorphic ventricular extrasystole and benign ventricular tachycardia.

Role of the Cardiologist in Management of Subarachnoid Haemorrhage

2002 ◽  
Vol 15 (5) ◽  
pp. 625-633 ◽  
Author(s):  
F. Gaita ◽  
L. Formato ◽  
F. Bianchi ◽  
L. Vivalda ◽  
C. Giustetto ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Subarachnoid Haemorrhage ◽  
Pulmonary Oedema ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Aneurysmal Subarachnoid Haemorrhage ◽  
Ecg Changes ◽  
St Segment ◽  
Ecg Abnormalities

Patients with aneurysmal subarachnoid haemorrhage (SAH) frequently have cardiovascular complications that include: blood pressure fluctuations, cardiac arrhythmias and ECG changes. ECG abnormalities, haemodynamic instability and pulmonary oedema, frequently associated with this pathologic condition, contribute to the morbidity and mortality of subarachnoid haemorrhage (SAH). Actually ECG changes occur in 50% to 100% of the patients during the acute stage of SAH, with the most common abnormalities involving the ST segment, T wave and QT interval. In most cases, these abnormalities are clinically inconsequential and are attributed to neurally mediated electrophysiological effects. Some SAH patients, however, show evidence of structural cardiac damage. ECG abnormalities which are indistinguishable from those due to acute myocardial infarction (ST segment elevation or depression) have occasionally been reported in SAH. These patients exhibited findings (which are completely reversible) similar to an acute myocardial infarction on ECG examination, as well as elevated cardiac enzymes and findings of left ventricular wall motion abnormalities, mostly anterior wall akynesis, causing the reduction of left ventricular ejection fraction. Occurrence of pulmonary oedema has been described in ten to 25% of SAH patients. Pulmonary oedema may be neurogenic or cardiogenic in origin and both are a consequence of increased adrenergic tone. There is evidence that the most important consequence of cardiovascular effects secondary to subarachnoid haemorrhage is increased susceptibility to sudden death. The increased adrenergic tone, due to high catecholamine levels and sympathetic cranial nerves stimulation can explain the origin of tachyarrhythmias. The mechanism proposed to explain the origin of bradyarrhythmias is an increased vagal tone.

Abnormal ST segment in electrocardiograph predicts poor outcome in patients with acute subarachnoid hemorrhage

2021 ◽  
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Left Ventricular ◽  
World Federation ◽  
High Heart Rate ◽  
Poor Outcome ◽  
St Segment ◽  
Surface Ecg ◽  
Acute Subarachnoid Hemorrhage ◽  
Ecg Abnormalities ◽  
Independent Indicator

Background and purpose: There are high occurrences of abnormal electrocardio-graphic (ECG) in patients with acute subarachnoid hemorrhage (SAH). Thus, we want to determine whether any specific characteristics in ECG are associated with poor clinical outcomes in patients with SAH inhospital. Methods: A total of 145 patient who selected from 270 cases with non-traumatic SAH was included in this study. A standard surface ECG was assessed for all patients within 72 hours of SAH onset. All patients were stratified into Good or Poor outcome groups according to the in-hospital mortality or neurological worsening (World Federation of Neurological Surgeons, WFNS class) when they discharge from our hospital. Results: These patients in Poor outcome (n = 29) had significantly high heart rate (93.52± 22.23 bpm vs 78.42 ± 18 bpm, P < 0.01), prolonged QTc (458.17 ± 44.88 ms vs 436.89 ± 43.46 ms, P = 0.027) and corrected Tpeak–Tend interval (cTp-e, 106.19 ± 22.22 ms vs 93.14 ± 21.04 ms, P = 0.007) and high occurrence of ECG abnormalities including ST segment (90% vs 44%, P < 0.01) and left ventricular high voltage (28%vs 10%, P = 0.03). Multivariable logistic regression identified independent variables indicating poor outcome in-hospital including abnormal ST (OR = 2.507, 95% CI, 1.051-5.941, P = 0.037) and WFNS class (OR = 2.280, 95% CI, 1.605-3.240, P < 0.001). Conclusions: Abnormal ST segment of ECG is an independent indicator for poor inhospital outcomes regardless the severity of patients with SAH and warrant to further study their mechanism in the future.

scholarly journals Carvedilol and Pycnogenol® improve the function of diabetic hearts in rats

2013 ◽  
Vol 60 (2) ◽  
pp. 15-21
Author(s):  
Kráľová E. ◽  
Jankyová S. ◽  
Pekárik A. ◽  
Čuboň J. ◽  
Stankovičová T.
Keyword(s):  
Blood Pressure ◽  
Electrical Activity ◽  
Qt Interval ◽  
Heart Function ◽  
Left Ventricular ◽  
Biometric Parameters ◽  
Haemodynamic Parameters ◽  
Arterial Blood ◽  
Prolonged Qt Interval ◽  
Prolonged Qt

Abstract We observed the changes in electrical activity, biometric and haemodynamic parameters of hearts in animals with experimental diabetes mellitus (DM). As well the effect of carvedilol, PycnogenolR and its combination with carvedilol on DM heart function was tested. DM was induced by streptozotocin over three sequential days at a dose of 25 mg/kg body weight i.p. We started therapy by suspension of carvedilol, PycnogenolR and their combination for six weeks. Blood pressure was measured using tail cuff plethysmography. ECG, haemodynamic and biometric parameters were measured in isolated hearts perfused according to the Langendorff. DM rats had increased systolic arterial blood pressure, thicker free wall of left ventricle but weakened myocardial contractility compared with controls. In contrast to controls, electrophysiological parameters showed prolonged QT interval and increased incidence of dysrhythmias in DM rats. The PycnogenolR administration induced regression of left ventricular hypertrophy, improved left ventriculi contraction and increased coronary flow; however, it did not improve the electrical activity of the myocardium compared with DM ones. Carvedilol also reversed the myocardial remodelling, shortened the duration of QT interval and suppressed the incidence of dysrhythmias. The common combination of drugs improved biometric and haemodynamic parameters compared with DM animals, however, not so significantly as monotherapy. On the other hand, the combination of carvedilol and PycnogenolR significantly reduced the duration of the QT interval and shortened the incidence of dysrhythmias. We can conclude that the administration of PycnogenolR effectively improved haemodynamic parameters, and carvedilol affected biometric parameters and also electrical parameters in DM animals. We observed the marked synergic effect of the combination of both drugs on the electrical activity of myocardium. This combination shortened the most pathologically prolonged QT interval and reduced the number of dysrhythmias.

ECG SIGNAL GENERATION AND HEART RATE VARIABILITY SIGNAL EXTRACTION: SIGNAL PROCESSING, FEATURES DETECTION, AND THEIR CORRELATION WITH CARDIAC DISEASES

2012 ◽  
Vol 12 (04) ◽  
pp. 1240012 ◽  
Author(s):  
GOUTHAM SWAPNA ◽  
DHANJOO N. GHISTA ◽  
ROSHAN JOY MARTIS ◽  
ALVIN P. C. ANG ◽  
SUBBHURAAM VINITHA SREE
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Sinus Bradycardia ◽  
Premature Ventricular Contraction ◽  
P Wave ◽  
Ecg Signal ◽  
Qrs Complex ◽  
T Wave ◽  
St Segment ◽  
Cardiac Disorders

The sum total of millions of cardiac cell depolarization potentials can be represented by an electrocardiogram (ECG). Inspection of the P–QRS–T wave allows for the identification of the cardiac bioelectrical health and disorders of a subject. In order to extract the important features of the ECG signal, the detection of the P wave, QRS complex, and ST segment is essential. Therefore, abnormalities of these ECG parameters are associated with cardiac disorders. In this work, an introduction to the genesis of the ECG is given, followed by a depiction of some abnormal ECG patterns and rhythms (associated with P–QRS–T wave parameters), which have come to be empirically correlated with cardiac disorders (such as sinus bradycardia, premature ventricular contraction, bundle-branch block, atrial flutter, and atrial fibrillation). We employed algorithms for ECG pattern analysis, for the accurate detection of the P wave, QRS complex, and ST segment of the ECG signal. We then catagorited and tabulated these cardiac disorders in terms of heart rate, PR interval, QRS width, and P wave amplitude. Finally, we discussed the characteristics and different methods (and their measures) of analyting the heart rate variability (HRV) signal, derived from the ECG waveform. The HRV signals are characterised in terms of these measures, then fed into classifiers for grouping into categories (for normal subjects and for disorders such as cardiac disorders and diabetes) for carrying out diagnosis.

fMLP provokes coronary vasoconstriction and myocardial ischemia in rabbits

1988 ◽  
Vol 254 (3) ◽  
pp. H481-H486 ◽  
Author(s):  
M. N. Gillespie ◽  
D. C. Booth ◽  
B. J. Friedman ◽  
M. R. Cunningham ◽  
M. Jay ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Inflammatory Cell ◽  
Coronary Spasm ◽  
Inflammatory Cells ◽  
Left Ventricular ◽  
Ecg Changes ◽  
St Segment ◽  
Perfusion Defects ◽  
The Right ◽  
Electrocardiogram Ecg

Recent pathological studies of coronary arteries from humans with suspected coronary spasm have revealed an augmented intramural burden of inflammatory cells. To test the hypothesis that inappropriate activation of inflammatory cells participates in the evolution of coronary vasospasm, the present experiments employed a newly developed coronary arteriographic technique for use in pentobarbital-anesthetized rabbits to evaluate the coronary vasomotor actions of the nonselective inflammatory cell stimulant, N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP). In 10 of 10 animals, selective left intracoronary injection of 200 ng fMLP evoked profound left coronary narrowing accompanied in all cases by ST segment deviation and dysrhythmias. Thallium-201 scintigraphy demonstrated hypoperfusion of the left ventricular free wall and septum supplied by the spastic coronary artery. The fMLP-induced epicardial vaso-constriction, ischemic electrocardiogram (ECG) changes, and thallium perfusion defects were reversed by intravenous nitroglycerin. Neither the right coronary artery nor its distribution were influenced by left coronary injection of fMLP. Additional experiments in isolated, salt solution-perfused rabbit hearts demonstrated that fMLP failed to exert direct coronary vasoconstrictor effects. These observations indicate that the non-selective inflammatory cell stimulant, fMLP, provokes arteriographically demonstrable coronary spasm with attendant myocardial hypoperfusion and ischemic ECG changes in anesthetized rabbits. Such a model may be useful in exploring the dynamic role of inflammatory cells in development of coronary spasm.

Independent Predictors of One-Month Mortality in Patients with Intracranial Hemorrhage; a Cohort study

2021 ◽  
Author(s):  
Hamid Kariman ◽  
Behnam Babadi ◽  
Masomeh Raofi ◽  
Saeed Safari
Keyword(s):  
Cohort Study ◽  
Basal Ganglia ◽  
Blood Sugar ◽  
Intracranial Hemorrhage ◽  
Left Ventricular ◽  
St Segment Elevation ◽  
Wave Inversion ◽  
St Segment ◽  
One Year ◽  
Ecg Abnormalities

Introduction: Predicting the outcome is one of the most frequent and important issues when approaching patients with intracranial hemorrhage (ICH). Objective: This study aimed to evaluate the correlation of SUSPEKT score variables plus electrocardiogram (ECG) abnormalities with one-month mortality of patients with ICH presenting to emergency department (ED). Methods: In this cohort study, adult patients presenting to the EDs of three educational hospitals, during one year, were followed and their one-month mortality rate as well as independent predictors of outcome among the variables of SUSPEKT score plus electrocardiography findings were evaluated. Results: One hundred seventy-seven patients with the mean age of 63.07±14.89 years were studied (59.9%). The most common locations of intra-parenchymal hemorrhage were basal ganglia (53.7%) and cortex (36.2%). Ninety-two (52.0%) of cases had at least one ECG abnormality. The most frequent ECG abnormalities were ST segment depression (20.3%), T wave inversion (16.4%), and left ventricular hypertrophy (14.7%). Thirty (16.9%) cases died during the 30-day follow-up. Survived and non-survived cases were significantly different regarding the location of intra-parenchymal hemorrhage (p < 0.0001), presence of intraventricular hemorrhage (IVH) (p = 0.007), ST segment elevation (p < 0.0001), bradycardia (p < 0.0001), tachycardia (p < 0.0001), arterial fibrillation (p < 0.0001), blood sugar (p = 0.044), and serum level of potassium (p = 0.022). Conclusions: The location of hemorrhage (basal ganglia), higher blood sugar, and presence of ECG abnormalities (ST segment elevation, tachycardia, bradycardia, atrial fibrillation) were among the independent predictors of one-month mortality of ICH patients in this study.

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