scholarly journals Serum inflammatory and oxidative stress biomarkers levels are associated with pain intensity, pressure pain threshold and quality of life in myofascial pain syndrome

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Seyed Kazem Shakouri ◽  
Neda Dolatkhah ◽  
Sepideh Omidbakhsh ◽  
Alireza Pishgahi ◽  
Maryam Hashemian
Keyword(s):  
Quality Of Life ◽  
Pain Intensity ◽  
Myofascial Pain ◽  
Pressure Pain Threshold ◽  
Pain Syndrome ◽  
Myofascial Pain Syndrome ◽  
Oxidative Stress Biomarkers ◽  
Hs Crp ◽  
And Oxidative Stress

Abstract Objectives We aimed to determine the serum concentrations of some inflammatory and oxidative stress biomarkers in relation with pain intensity and quality of life in patients with myofascial pain syndrome (MPS) compared to healthy controls. This study is a case–control study. The participants were selected from MPS patients who referred to rehabilitation outpatient clinics of the Tabriz University of Medical Sciences, Iran. Results Serum hs-CRP (4.68 ± 4.36 vs. 2.92 ± 4.55 g/mlµ respectively, p = 0.011), phospholipase A2 (PLA2) (6.81 ± 2.22 vs. 4.73 ± 2.97 pg/ml respectively, p < 0.001) and malondialdehyde (MDA) (2.63 ± 0.71 vs. 1.98 ± 0.90 nmol/ml respectively, p < 0.001) levels were significantly higher and serum total antioxidant capacity (TAC) (2.46 ± 0.49 vs. 2.83 ± 0.82 mmol/L respectively, p = 0.011) and superoxide dismutase (SOD) (78.89 ± 37.93 vs. 154.25 ± 115.93 U/ml respectively, p < 0.001) levels were significantly lower in the MPS patients compared to healthy controls. Serum high-sensitivity C-reactive protein (hs-CRP) level was significantly and positively associated with resting (r = 0.349, p = 0.019), activity (r = 0.295, p = 0.049) and night pain (r = 0.304, p = 0.043) intensities, pressure pain threshold (PPT) (r = 0.210, p = 0.047) and pain duration (r = 0.283, p = 0.007). Serum TAC level was significantly and negatively associated with resting pain intensity (r = −0.312, p = 0.037). Some scales and subscales of quality of life were positively correlated with serum TAC level and negatively associated with serum hs-CRP and PLA2 levels.

The Therapeutic Effects of Acupuncture on Patients with Chronic Neck Myofascial Pain Syndrome: A Single-Blind Randomized Controlled Trial

2010 ◽  
Vol 38 (05) ◽  
pp. 849-859 ◽  
Author(s):  
Mei-Yuan Sun ◽  
Ching-Liang Hsieh ◽  
Yung-Yen Cheng ◽  
Hung-Chang Hung ◽  
Tsai-Chung Li ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Randomized Controlled Trial ◽  
Myofascial Pain ◽  
Short Form ◽  
Controlled Trial ◽  
Pain Syndrome ◽  
Myofascial Pain Syndrome ◽  
Randomized Controlled ◽  
Single Blind

Chronic neck myofascial pain syndrome (MPS) is a common disorder seen in clinics. There is no gold standard method to treat myofascial pain. We investigated the effects of acupuncture on patients with chronic neck MPS by a single-blind randomized controlled trial. A total of 35 patients were randomly allocated to an acupuncture group (AG) or a sham acupuncture group (SG). Each subject received acupuncture treatment twice per week for three consecutive weeks. The primary outcome measure was quality of life as assessed with Short Form-36, and secondary outcome measures were neck range of motion (ROM), motion-related pain, and Short-Form McGill Pain Questionnaire (SF-MPQ), as determined by a blinded investigator. The clinical assessments were made before treatment (BT) and after six acupuncture treatments (AT), as well as four weeks (F1) and 12 weeks (F2) after the end of the treatment. A total of 34 patients completed the trial. The results indicated that there is no significant difference in the ROM, motion-related pain, and SF-MPQ scores between AG and SG at AT, F1 and F2 (all p > 0.05). However, AG has greater improvement in physical functioning and role emotional of Short Form-36 quality of life at F2. The results indicate that acupuncture may be used to improve the quality of life in patients with chronic neck MPS.

scholarly journals Safety and Efficacy of PrabotulinumtoxinA (Nabota®) Injection for Cervical and Shoulder Girdle Myofascial Pain Syndrome: A Pilot Study

Toxins ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 355 ◽  
Author(s):  
Da-ye Kim ◽  
Jae Kim
Keyword(s):  
Quality Of Life ◽  
Pilot Study ◽  
Myofascial Pain ◽  
Neck Disability Index ◽  
Pain Syndrome ◽  
Myofascial Pain Syndrome ◽  
Shoulder Girdle ◽  
Painful Condition ◽  
Pain Scores

Myofascial pain syndrome is a common painful condition encountered in the general population. Previous studies evaluating the efficacy of botulinum toxin for the treatment of myofascial pain syndrome are limited, with variable results. This prospective study investigated the efficacy and safety of direct injection of Prabotulinumtoxin A (Nabota®) into painful muscle groups for cervical and shoulder girdle myofascial pain. Twelve patients with chronic myofascial pain syndrome of the neck and shoulder underwent an injection of Prabotulinumtoxin A. Painful muscles containing trigger points were injected in the mid-belly. Pain scores and quality of life measurements were assessed at baseline, as well as 6 weeks and 12 weeks post-injection. Safety and tolerability were also assessed. This trial is registered under clinical research information service (CRIS) number KCT0001634. Patients injected with Prabotulinumtoxin A showed a significant improvement in pain at 12 weeks (p < 0.001). At 6 weeks, the pain had not significantly improved compared with baseline (p = 0.063). However, at that time, 41.7% of patients were characterized as Prabotulinumtoxin A responders, with a 30% reduction in pain rating score compared to baseline. In the Neck Disability Index scores, the patients demonstrated significant improvement at both 6 weeks and 12 weeks. No serious adverse effects occurred during the study. Prabotulinumtoxin A injection into chronically painful muscles associated with cervical and shoulder girdle myofascial pain syndrome resulted in an improvement in pain scores and quality of life lasting at least 12 weeks. Additionally, the injections were well tolerated. As these are preliminary findings in a pilot study, future studies should carefully consider using randomized, controlled, prospective trials.

Myofascial pain syndrome after head and neck cancer treatment: Prevalence, risk factors, and influence on quality of life

Head & Neck ◽  
2014 ◽  
Vol 37 (12) ◽  
pp. 1733-1737 ◽  
Author(s):  
Leticia Rodrigues Cardoso ◽  
Cláudia Carvalho Rizzo ◽  
Cleyton Zanardo de Oliveira ◽  
Carlos Roberto dos Santos ◽  
André Lopes Carvalho
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Head And Neck Cancer ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Myofascial Pain ◽  
Pain Syndrome ◽  
Myofascial Pain Syndrome ◽  
Treatment Prevalence

scholarly journals Investigation of Effectiveness of Two Different Kinesiotaping Techniques in Myofascial Pain Syndrome: An Open-Label Randomized Clinical Trial

2021 ◽  
Vol 24 (6) ◽  
pp. E721-E731
Keyword(s):  
Quality Of Life ◽  
Functional Status ◽  
Myofascial Pain ◽  
Exercise Program ◽  
Pain Syndrome ◽  
Myofascial Pain Syndrome ◽  
Home Exercise ◽  
Upper Trapezius ◽  
Muscle Inhibition

BACKGROUND: Myofascial pain syndrome is a regional musculoskeletal pain syndrome characterized by trigger points. Although there are widely accepted treatment modalities, there is no gold standard treatment. Kinesiotaping represents an interesting modality in the treatment of musculoskeletal disorders and attracts attention with studies emerging in the recent years, but in spite of the proposed benefits of kinesiotaping, its efficacy is still unclear, thus further studies evaluating the effectiveness of kinesiotaping are needed. OBJECTIVES: We aimed to investigate, not only the effectiveness of kinesiotaping applied with the space correction and muscle inhibition techniques (compared to the home exercise program in reducing pain and improving functional status and quality of life in female patients with myofascial pain syndrome related to active trigger points in the upper trapezius), but also to evaluate the superiority of the 2 techniques over each other. STUDY DESIGN: An open-label randomized clinical trial with a parallel assignment intervention model. SETTING: The physical medicine and rehabilitation clinics in Istanbul University, Istanbul Faculty of Medicine. METHODS: Seventy-one female patients with the complaint of pain in the upper trapezius region, diagnosed with myofascial pain syndrome, and having at least one active trigger point in the upper trapezius fibers, were randomly assigned by a computer program to 1 of the 3 groups: kinesiotaping with the space correction technique (KSCT, n = 20), kinesiotaping with the muscle inhibition technique (KMIT, n = 24), and the home exercise program alone (control group [CG], n = 27). The patients were evaluated by the numerical rating scale for pain intensity, the neck disability index for functional status, and the 36-Item Short-Form Health Survey for quality of life in the beginning of the study and at the first, second, and sixth weeks (1-month follow-up). RESULTS: Kinesiotaping was associated with lower pain intensity levels (P = 0.019 at the first week and P = 0.026 at the second week) and better functional status (P = 0.011 at the second week) and it was effective in increasing quality of life by improving physical functions and general health (P = 0.033 and P = 0.003 at the second week, respectively) earlier than in the CG. Role limitations due to physical factors improved in the KMIT group earlier than in the other groups (P = 0.022 at the second week). LIMITATIONS: Being performed in a limited number of female patients only, absence of a placebo group, and lack of blinded assessments. CONCLUSION: Both kinesiotaping methods were associated with lower pain intensity levels and better functional status and were effective in increasing quality of life by improving physical functions and general health earlier than the home exercise program. There was no significant difference between the kinesiotaping methods, except for role limitations due to the physical factors domain of SF-36 which was improved in the KMIT group earlier than in the KSCT group and CGs. KEY WORDS: Myofascial pain syndrome, myofascial trigger point pain, trapezius, kinesiotape, muscle inhibition technique, space correction technique

scholarly journals Impact of dry needling and ischemic pressure in the myofascial syndrome: controlled clinical trial

2014 ◽  
Vol 27 (4) ◽  
pp. 515-522 ◽  
Author(s):  
Rebeka Borba da Costa Santos ◽  
Maíra Izzadora Souza Carneiro ◽  
Déborah Marques de Oliveira ◽  
Adriana Baltar do Rêgo Maciel ◽  
Kátia Karina do Monte-Silva ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Myofascial Pain ◽  
Demographic Data ◽  
Pain Syndrome ◽  
Myofascial Pain Syndrome ◽  
Controlled Clinical Trial ◽  
Dry Needling ◽  
Significant Difference ◽  
Before And After

Introduction Musculoskeletal pain is a common clinical condition and about 10% of the population have musculoskeletal disorder. Objective The aim of this study was to evaluate whether ischemic pressure and dry needling techniques are able to reduce the pain of patients with myofascial pain syndrome. Method 22 patients aged 20-75 years were randomized into 3 groups: ischemic pressure (IPG = 8), dry needling (DNG = 7) and control (CG = 7). Patients in the IPG and DNG were assessed before and after 10 intervention sessions, which occurred 3 times per week. The CG was assessed initially and reassessed three weeks later. The assessment of pain was done through Visual Analogic Scale (VAS) and quality of life through WHOQOL-BREF (5 domains: global, physical, psychological, social and environmental). Results There was no significant difference for clinical and demographic data of all groups at baseline, except for age (p = 0.042). The results of the VAS expressed that IPG had pain relief in most sessions, the same was not observed for DNG. Comparing the 2 groups was obtained difference in the 4th and 8th sessions. The results of the WHOQOL-BREF showed that the three groups had a significant increase in the psychological domain. The same was not true for global domains, physical, environmental and social. Conclusion Ischemic pressure and dry needling were able to reduce the pain of patients and also change their quality of life, specifically the psychological aspect.

scholarly journals Effectiveness of Bupivacaine Trigger Points Injections in the Treatment of Myofascial Pain Syndrome

2020 ◽  
Vol 1 (1) ◽  
pp. 23-28
Author(s):  
Rabiu Mohammed Bashir ◽  
Afeez Abdulrahman ◽  
Zakari Suleiman
Keyword(s):  
Quality Of Life ◽  
Rating Scale ◽  
Myofascial Pain ◽  
Pain Syndrome ◽  
Myofascial Pain Syndrome ◽  
Trigger Points ◽  
Hypodermic Needle ◽  
Myofascial Trigger Points ◽  
Pain Disability

Background: Myofascial pain syndrome is a regional or widespread muscular pain associated with tenderness localized to linear or nodular hardening, trigger points in one or group of muscles. It is a major cause of time loss from work and low quality of life. Injections of myofascial trigger points either with local anaesthetics, steroid, normal saline or without any agent have been proven to provide pain relief. This study aims to determine the effectiveness of trigger point injection with bupivacaine in treatment of myofascial pain syndrome and improvement in quality of life. Methods: After Institutional Ethical Committee approval, forty one patients aged 16 years and above with myofacial pain syndrome had 0.5mls of 0.25% plain bupivacaine trigger points injections with size 26G 11 /2 inch hypodermic needle. Pain was assessed using Numerical Rating Scale and Pain disability questionnaire was administered to all the patients before the procedures and 1 month post-intervention (follow-up visits) to assessed functional and psychological component of pain disability scale and their response to treatment. Results:

scholarly journals Effect of a Bioenergy Economy Program on the Severity of Symptoms and Quality of Life of Patients With Myofascial Pain Syndrome

2020 ◽  
Author(s):  
Farzad Goli ◽  
Reihaneh Yekta ◽  
Carl Eduard Scheidt ◽  
Amirreza Boroumand ◽  
Reza Johari Fard ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Myofascial Pain ◽  
Pain Syndrome ◽  
Myofascial Pain Syndrome ◽  
Depression And Anxiety ◽  
Women Patients ◽  
Significant Difference ◽  
Post Test ◽  
The Mean

The aim of this study was to investigate the effect of a bioenergy economy-based program on the intensity of symptoms and quality of life among patients with myofascial pain syndrome. To collect the data, a simple random sampling was used among the women patients with MPS referred from a neurological clinic in Mashhad. Fifteen patients were collected as an experimental group. The method consisted of a quasiexperimental method with a pre-test, post-test, and follow-ups in two and six months after the program. Data collection main materials included the McGill Pain Questionnaire (MPQ) and WHO Quality of Life -BREF Questionnaire (WHOQOL-BREF). Moreover, Beck Depression Inventory-II (BDI-II) and the Beck Anxiety Inventory were used to increase the quality of the research. The group underwent six sessions of bioenergy economy-based program. Data collected were analyzed using repeated-measures analysis of variance (ANOVA) to reach the aim of the study. The mean score of pain intensity and depression had a significant difference in the post-test and the two follow-ups with the pre-test. The mean score of the anxiety had a significant difference in the pre-test and post-test but not in the follow-ups. The mean score of quality of life did not have a significant difference in the pre-test, post-test, and follow-ups even in the sub-scales, but the mean score of the post-test and the follow-ups were higher than the pre-test. Bioenergy economy-based program caused a significant decrease in the pain intensity, depression, and anxiety in women patients with MPS and remained consistent in the two and six month’s follow-ups. Even in the quality of life, there was an improvement after the program, and although the fluctuation in the score, the mean score after six months was lower than before the program. To conclude, a bioenergy economy-based program can be an effective program in lowering the pain, depression, and anxiety and improving the quality of life in women patients with myofascial pain syndrome, and this remains consistent in the following six months. © 2019 Tehran University of Medical Sciences. All rights reserved.

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