scholarly journals A pilot investigation of emotional regulation difficulties and mindfulness-based strategies in manic and remitted bipolar I disorder and major depressive disorder

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Christie W. Musket ◽  
Natasha S. Hansen ◽  
Keith M. Welker ◽  
Kirsten E. Gilbert ◽  
June Gruber
Keyword(s):  
Major Depressive Disorder ◽  
Emotion Regulation ◽  
Depressive Disorder ◽  
Emotional Regulation ◽  
Preliminary Investigation ◽  
Major Depressive ◽  
Bipolar I Disorder ◽  
Difficulties In Emotion Regulation ◽  
Specific Emotion ◽  
Pilot Investigation

Abstract Background Both bipolar disorder and major depressive disorder are characterized by difficulties in emotion regulation. Little is known about which specific emotion regulatory patterns may be transdiagnostic versus disorder specific, and how such patterns change as a function of current mood states. Methods This preliminary investigation examined specific patterns of self-reported trait emotion regulation difficulties and mindfulness-based regulations strategies across four groups: remitted adults with bipolar I disorder (BD-remitted; n = 32), currently manic adults with bipolar I disorder (BD-manic; n = 19), remitted adults with major depressive disorder (MDD-remitted; n = 32), and healthy controls (CTL; n = 30). Results All three clinical groups reported significantly greater difficulties with emotion regulation and decreased overall mindfulness-based strategies. Conclusions These results suggest that increased emotion regulation difficulties, decreased mindfulness, and increased emotion-driven impulsivity may be transdiagnostic across mood disorders and states, and that impulsivity may be particularly impaired during periods of mania.

T141. Emotion Regulation Abnormalities in Young Adults With Major Depressive Disorder and Adolescent Frequent Marijuana Use

2018 ◽  
Vol 83 (9) ◽  
pp. S183
Author(s):  
Jacob Penner ◽  
Kristen Ford ◽  
Justin Arcaro ◽  
Michael Wammes ◽  
Richard Neufeld ◽  
...  
Keyword(s):  
Young Adults ◽  
Major Depressive Disorder ◽  
Emotion Regulation ◽  
Depressive Disorder ◽  
Marijuana Use ◽  
Major Depressive

scholarly journals The effect of bipolar I disorder and major depressive disorder on workforce function

2008 ◽  
Vol 28 (3) ◽  
pp. 84-91 ◽  
Author(s):  
R.S. McIntyre ◽  
K. Wilkins ◽  
H. Gilmour ◽  
J.K. Soczynska ◽  
J.Z. Konarksi ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Canadian Community Health Survey ◽  
Job Security ◽  
Annual Income ◽  
Major Depressive ◽  
Bipolar I Disorder ◽  
Assistance Programs ◽  
The Past ◽  
Community Health Survey

This investigation was undertaken to explore and compare the effect of bipolar I disorder (BD) and major depressive disorder (MDD) on workforce function. The data for this analysis were procured from the Canadian Community Health Survey (CCHS 1.2). The sample consisted of 20 747 individuals (≥ 18 years old and currently working); the proportions screening positive for lifetime BD and MDD were 2.4% and 11.2%, respectively. Individuals with BD or MDD had a signifi cantly lower mean annual income, compared to people without these disorders. Individuals with BD had a signifi cantly lower annual income when compared to MDD (p $lt; 0.05). Results from a multiple logistic regression also indicate that employed individuals with BD had greater odds of reporting one or more mental health disability days in the past two weeks, compared with those with MDD (OR = 1.6; 95% CI = 1.0 to 2.6). Currently employed individuals with BD had lower odds of “good job security” relative to those with MDD (OR = 0.6 95% CI = 0.5 to 0.9). The data herein underscore the pernicious effect of BD on workforce function, and suggest that opportunistic screening for BD in all individuals utilizing employment assistance programs for depression might be warranted.

Role of obesity in systemic low-grade inflammation and cognitive function in patients with bipolar I disorder or major depressive disorder

CNS Spectrums ◽  
2020 ◽  
pp. 1-7
Author(s):  
Mu-Hong Chen ◽  
Ju-Wei Hsu ◽  
Kai-Lin Huang ◽  
Shih-Jen Tsai ◽  
Tung-Ping Su ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Cognitive Function ◽  
Depressive Disorder ◽  
Affective Disorder ◽  
Systemic Inflammation ◽  
Proinflammatory Cytokines ◽  
Major Depressive ◽  
Bipolar I Disorder ◽  
Tnf Α ◽  
Α Level

Abstract Background. Studies have suggested the detrimental effects of obesity and systemic inflammation on the cognitive function of patients with bipolar or major depressive disorder. However, the complex associations between affective disorder, obesity, systemic inflammation, and cognitive dysfunction remain unclear. Methods. Overall, 110 patients with affective disorder (59 with bipolar I disorder and 51 with major depressive disorder) who scored ≥61 on the Global Assessment of Functioning and 51 age- and sex-matched controls were enrolled. Body mass index ≥25 kg/m2 was defined as obesity or overweight. Levels of proinflammatory cytokines—including interleukin-6, tumor necrosis factor (TNF)-α, and C-reactive protein (CRP)—were measured, and cognitive function was assessed using various methods, including the Wisconsin Card Sorting Test (WCST) and go/no-go task. Results. Patients with bipolar I disorder or major depressive disorder were more likely to be obese or overweight, had higher CRP and TNF-α levels, and had greater executive dysfunction in the WCST than the controls. TNF-α level (P < .05) but not affective disorder diagnosis or obesity/overweight was significantly associated with cognitive function deficits, although obesity/overweight and diagnosis were significantly associated with increased TNF-α level. Conclusions. Our findings may indicate that proinflammatory cytokines, but not obesity or overweight, have crucial effects on cognitive function in patients with bipolar I disorder or major depressive disorder, although proinflammatory cytokines and obesity or overweight were found to be strongly associated. The complex relationships between affective disorder diagnosis, proinflammatory cytokine levels, obesity or overweight, and cognitive function require further investigation.

Antidepressant-Associated Mood Elevations in Bipolar II Disorder Compared With Bipolar I Disorder and Major Depressive Disorder

2008 ◽  
Vol 69 (10) ◽  
pp. 1589-1601 ◽  
Author(s):  
David J. Bond ◽  
Melissa M. Noronha ◽  
Marcia Kauer-Sant'Anna ◽  
Raymond W. Lam ◽  
Lakshmi N. Yatham
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Major Depressive ◽  
Bipolar Ii Disorder ◽  
Bipolar I Disorder ◽  
Bipolar Ii

Cognitive reappraisal modulates performance following negative feedback in patients with major depressive disorder

2010 ◽  
Vol 40 (10) ◽  
pp. 1703-1710 ◽  
Author(s):  
A.-K. Fladung ◽  
U. Baron ◽  
I. Gunst ◽  
M. Kiefer
Keyword(s):  
Major Depressive Disorder ◽  
Emotion Regulation ◽  
Depressive Disorder ◽  
Negative Feedback ◽  
Task Difficulty ◽  
Cognitive Reappraisal ◽  
Absolute Number ◽  
Major Depressive ◽  
Impaired Performance ◽  
Depressed Patients

BackgroundDepressed patients show impaired performance following negative feedback; the probability of committing an error is increased immediately after an error. This deficit is assumed to be highly specific and to represent a trait marker of major depressive disorder (MDD). Inconsistencies in currently available data could reflect inter-individually different strategies to regulate negative affect. The present study examined modulation of performance following negative feedback by cognitive reappraisal to regulate aversive affect in depressed patients.MethodThirty-three depressed patients and 33 control subjects performed tasks of varying difficulty over a prolonged time. Emotional feedback was given immediately after each trial. Performance was further analysed within subgroups using cognitive reappraisal of aversive events with high and low frequency.ResultsA significant group by task difficulty interaction for absolute number of subsequent errors revealed that depressed patients were especially impaired when receiving negative feedback more frequently. An increased probability of subsequent errors was shown in patients irrespective of task difficulty. Analysis of subgroups revealed higher absolute number and probability of subsequent errors only in depressed patients habitually not using cognitive reappraisal to regulate aversive emotions. Depressed patients using this strategy did not differ from controls.ConclusionsThe present results replicate the observation of impaired performance in depressed patients following failure feedback. Most importantly, a subgroup of patients who habitually rely on cognitive reappraisal of aversion-eliciting events, such as negative performance feedback, was not impaired. This modulatory influence of emotion regulation strategies on performance subsequent to negative feedback suggests that training emotion regulation in achievement situations should be incorporated in current concepts to prevent relapse.

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