scholarly journals Successful conversion surgery for unresectable gastric cancer with giant para-aortic lymph node metastasis after downsizing chemotherapy with S-1 and oxaliplatin: a case report

2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Akiko Serizawa ◽  
Kiyoaki Taniguchi ◽  
Takuji Yamada ◽  
Kunihiko Amano ◽  
Sho Kotake ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Case Report ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Conversion Surgery ◽  
Node Metastasis ◽  
Aortic Lymph Node ◽  
Unresectable Gastric Cancer

scholarly journals A case of stage IV gastric cancer with para-aortic lymph node metastasis showing pathological complete response after neoadjuvant chemotherapy

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Yuki Katsura ◽  
Takehiro Okabayashi ◽  
Manabu Matsumoto ◽  
Kazuhide Ozaki ◽  
Yuichi Shibuya
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Pathological Complete Response ◽  
Stage Iv ◽  
Complete Response ◽  
Conversion Surgery ◽  
Stage Iv Gastric Cancer ◽  
Node Metastasis ◽  
Aortic Lymph Node

Abstract Background Stage IV advanced gastric cancer with para-aortic lymph node metastasis (PALM) is considered unresectable. Systemic chemotherapy is the treatment of choice for such tumors, while conversion surgery may be a treatment option in the case chemotherapy is effective but R0 resection is possible. We report a case of stage IV gastric cancer with PALM that showed pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) using S-1, oxaliplatin, and trastuzumab (SOX+HER). Case presentation A 69-year-old woman who was diagnosed with type 4 stage IV gastric cancer with PALM underwent five courses of NAC with the SOX+HER regimen. The primary tumor and the PALM shrank after treatment, suggesting that the NAC induced a partial response. We performed a total gastrectomy plus distal pancreaticosplenectomy with para-aortic lymph node dissection. Histological analysis revealed no remnant cancer cells in the primary tumor or the lymph nodes, confirming a pCR. The postoperative course was uneventful, and the patient was discharged on day 14 after the operation. S-1 was started as adjuvant chemotherapy, and the patient remains alive without recurrence 2 months after surgery. Conclusion This case shows the possibility of conversion surgery after SOX+HER therapy for stage IV advanced gastric cancer with PALM.

59. Efficacy of surgical treatment for responders to chemotherapy for gastric cancer with para-aortic lymph node metastasis

2016 ◽  
Vol 42 (9) ◽  
pp. S89-S90
Author(s):  
Y. Tanizawa ◽  
E. Bando ◽  
M. Tokunaga ◽  
T. Kawamura ◽  
R. Makuuchi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Surgical Treatment ◽  
Lymph Node Metastasis ◽  
Node Metastasis ◽  
Aortic Lymph Node

scholarly journals THERAPEUTIC RESULTS OF GASTRIC CANCER WITH PARA-AORTIC LYMPH NODE METASTASIS

1994 ◽  
Vol 55 (7) ◽  
pp. 1660-1666
Author(s):  
Kazuhisa YABUSHITA ◽  
Kohji KONISHI ◽  
Yoshitaka KURODA ◽  
Osamu TAKADA ◽  
Takuya NAGATA ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis ◽  
Aortic Lymph Node ◽  
Therapeutic Results
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