scholarly journals Digital gangrene as an unusual paraneoplastic manifestation of hodgkins lymphoma—a rare case report

2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Swaroopa Deme ◽  
Bhaskar Kakarla ◽  
Venkateswar Rao P. ◽  
Raju YSN ◽  
Nageswara Rao M.
Keyword(s):  
Case Report ◽  
Hodgkin’S Lymphoma ◽  
Ring Finger ◽  
Middle Finger ◽  
Hodgkin's Lymphoma ◽  
Severe Thrombocytopenia ◽  
Digital Ischemia ◽  
Rare Case Report ◽  
Generalized Lymphadenopathy ◽  
The Right

Abstract Background Hodgkin’s lymphoma presenting with digital ischemia and gangrene is a rare manifestation. Paraneoplastic manifestations are rare in Hodgkin’s lymphoma but can occur in the form of paraneoplastic cerebellar degeneration (PCD) and dermatomyositis/polymyositis. This case report adds an exceptional presentation of Hodgkin's lymphoma as digital ischemia and gangrene. Case presentation We report a case of a 60-year-old male patient who presented with fever, cough, shortness of breath, the pain in the right middle finger. On examination bluish-black discoloration of the right middle finger, left middle finger, ring finger, and generalized lymphadenopathy was noted. On further evaluation, he was found to have anemia, eosinophilia, and severe thrombocytopenia with a normal coagulation profile and negative rheumatological workup. Arterial Doppler of both upper limbs showed the normal study. He was diagnosed to have Hodgkin’s lymphoma on the lymph node and bone marrow biopsy. He was started on chemotherapy with partial improvement in symptoms and was lost to follow-up after 2 cycles. Conclusions Digital ischemia can be a rare paraneoplastic manifestation of Hodgkin’s lymphoma.

scholarly journals Chylous Effusions (Pleural Effusion and Ascites) due to Non-Hodgkin’s Lymphoma A Case Report

2019 ◽  
Vol 47 (2) ◽  
pp. 38-40
Author(s):  
Md Rafiqul Alam ◽  
Md Nazmul Hasan ◽  
Md Abdur Rahim ◽  
Quazi Mamtaz Uddin Ahmed ◽  
Md Syedul Islam ◽  
...  
Keyword(s):  
Case Report ◽  
Pleural Effusion ◽  
Hodgkin’S Lymphoma ◽  
Chylous Ascites ◽  
Lymphatic Drainage ◽  
Hodgkin's Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Direct Infiltration ◽  
Generalized Lymphadenopathy

Lymphoma can present with different type of serous effusion like pleural, pericardial and ascites  and it signifies poor outcome .Pleural effusions are the most common type among these. Ascites and pericardial effusion are rare. Effusion can be can be caused by direct infiltration and impairment of the lymphatic drainage .Several  investigations are available like study of the fluid for cytological, biochemical, immunohistochemistry and cytogenetics  study to assess the qualities of effusion and make a quick diagnosis. This present case report will describe a case of 40 year old female patient with non-Hodgkin’s lymphoma (NHL) presented with generalized lymphadenopathy and chylous ascites and pleural effusion. Bangladesh Med J. 2018 May; 47 (2): 38-40

scholarly journals Primary non-Hodgkin's lymphoma of the infratemporal fossa: a rare case report

2009 ◽  
Vol 1 (1) ◽  
Author(s):  
Jagdeep S Thakur ◽  
Ravinder S Minhas ◽  
Narinder K Mohindroo ◽  
Dev R Sharma ◽  
Shobha Mohindroo ◽  
...  
Keyword(s):  
Case Report ◽  
Hodgkin’S Lymphoma ◽  
Rare Case ◽  
Infratemporal Fossa ◽  
Hodgkin's Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Rare Case Report

scholarly journals Non-Hodgkin's lymphoma of the maxilla: A rare case report and review

2017 ◽  
Vol 4 (1) ◽  
pp. 51 ◽  
Author(s):  
Arpita Kabiraj ◽  
Rajarshi Banerjee ◽  
ArupK Ghosh ◽  
Mayukh Misra
Keyword(s):  
Case Report ◽  
Hodgkin’S Lymphoma ◽  
Rare Case ◽  
Hodgkin's Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Rare Case Report

TUBERCULOUS TENOSYNOVITIS OF FLEXOR TENDON PRESENTING AS MASS ON THE PALMAR ASPECT OF RIGHT RING FINGER: A RARE CASE REPORT

2021 ◽  
pp. 37-39
Author(s):  
Rajesh K Ambulgekar ◽  
Rahul S Agrawal
Keyword(s):  
Risk Factors ◽  
Case Report ◽  
Rare Case ◽  
Flexor Tendon ◽  
Ring Finger ◽  
Rare Case Report ◽  
Associated Risk Factors ◽  
The Right ◽  
Tuberculous Tenosynovitis ◽  
Palmar Aspect

Infectious tuberculous tenosynovitis is an exceptional location of musculoskeletal tuberculosis involving exor tendon of the nger. The patient was a 38 year old female of tuberculous exor tendon presenting as a mass on the palmar aspect of the right hand & ring nger without any other pulmonary or extrapulmonary tubercular manifestation. This report highlights the occurrence of tuberculous tenosynovitis in our environment in patients with associated risk factors for early diagnosis and treatment.

scholarly journals Digital Ischemia as an Unusual Manifestation of Hodgkin’s Lymphoma

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Fiorella Villano ◽  
Adriana Peixoto ◽  
Eloísa Riva ◽  
Carina Di Matteo ◽  
Lilián Díaz
Keyword(s):  
Hodgkin’S Lymphoma ◽  
Connective Tissue Diseases ◽  
Hodgkin's Lymphoma ◽  
Male Smoker ◽  
Digital Ischemia ◽  
Night Sweats ◽  
History Of ◽  
Painless Mass ◽  
The Right ◽  
Vascular Syndromes

Digital ischemia is associated with atherosclerotic, thromboembolic, or connective tissue diseases. Less often, it can be related to malignancy. Paraneoplastic vascular acrosyndromes (Raynaud’s syndrome, acrocianosis, and acronecrosis) are associated with adenocarcinoma and less frequently with hematological malignancies. We report the case of a 45-year-old male, smoker, with a 10-day history of pain, cyanosis, and progressive digital necrosis in both hands. In the previous four months, he noticed painless mass in the right axillary gap, drenching night sweats, and weight loss. Physical examination at admission highlighted necrotic lesions on the distal phalanges of both hands (except the thumbs), enlarged lymph nodes in right axillary, and right supraclavicular gaps. Arteriography of upper limbs demonstrated a distal stop in all bilateral digital arteries. Digital ischemia was interpreted as a paraneoplastic phenomenon after other common etiologies were ruled out. Amputation of three phalanges was required due to necrosis. Biopsy of axillary nodes demonstrated nodular sclerosis classical Hodgkin’s lymphoma (HL). The patient started conventional ABVD protocol (doxorubicin, bleomycin, vinblastine, and dacarbazine). After 6 cycles, he remained asymptomatic and symptoms of digital ischemia were completely resolved. It was concluded that the presence of acral vascular syndromes should alert the physician about the possibility of underlying malignant disease. Prompt investigation and treatment should be rapidly performed to avoid digital sequelae.

scholarly journals Eosinophilia as a first sign of Hodgkin´s lymphoma: A case report

2017 ◽  
Vol 74 (6) ◽  
pp. 581-584
Author(s):  
Rajko Milosevic ◽  
Danijela Lekovic ◽  
Nebojsa Antonijevic ◽  
Andrija Bogdanovic
Keyword(s):  
Case Report ◽  
Lymph Nodes ◽  
Hodgkin’S Lymphoma ◽  
Eosinophilic Granuloma ◽  
Clinical Stage ◽  
Hodgkin's Lymphoma ◽  
Ann Arbor ◽  
Prognostic Importance ◽  
The Right ◽  
Staging Classification

Introduction. It is well known that eosinophilia appears in a malignant disease. Frequency of all Hodgkin`s lymphoma patients is estimated to about 15%. Prognostic importance of this phenomenon is not completely investigated. Therefore we decided to present a female patient with eosinophilia, six months before lymphoma appearance. Case report. We presented a 51- years old female, from Serbia, who had eosinophilia (1,530?2,040 eosinophils per ?L of blood), six months before Hodgkin's lymphoma appearance. Eosinophilic granuloma was confirmed by tumor?s biopsy and histopathologic examination, from the right femoral region. As eosinophilia was increasing, lymph nodes became enlarged (120 ? 65 mm diameter), in the right parailiac region. All infectious and allergic examinations did not reveal eosinophilia's cause. Histopathologic revision was made with added immunohistochemical stains 17 months after tumor's biopsy. The diagnosis was changed from eosinophilic granuloma to mixed cellularity Hodgkin's lymphoma. After conducted Ann Arbor staging classification, II B clinical stage was established. The treatment was done by chemotherapy according to adriamycin, bleomycin, vinblastine, dacarbarine (ABVD) protocol, with 6 courses. Complete remission of the disease was achieved after 4 courses. Eosinophils number dropped to 640 per ?l blood. Conclusion. Eosinophilia without revealed cause can precede Hodgkin's lymphoma. We suggest careful search for enlarged lymph nodes, anywhere in the patients? body who suffer from eosinophilia. Timely and accurate histopathologic diagnostic is a right way to resolve such conditions.

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