Cannabis and the Peripheral Nervous System

1977 ◽  
Vol 131 (4) ◽  
pp. 361-365 ◽  
Author(s):  
M. Dibenedetto ◽  
H. B. McNamee ◽  
J. C. Kuehnle ◽  
J. H. Mendelson
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Nerve Conduction ◽  
Sensory Nerve ◽  
Baseline Period ◽  
Nerve Conduction Studies ◽  
Nerve Function ◽  
Heavy Users ◽  
Peripheral Nerve Function ◽  
Male Subjects

The possible ill-effects of cannabis on the peripheral nervous system were examined in 27 male subjects with respect to their motor and sensory nerve conduction. They were classified by their previous cannabis use into casual and heavy users. The nerve conduction studies were done after a baseline period of five days and then repeated after a three-week period during which the subjects could acquire and smoke standardized cannabis cigarettes. The casual users smoked a mean of 54·3 and the heavy users a mean of 109·5, cigarettes during the smoking period. No deterioration of peripheral nerve function could be demonstrated.

scholarly journals PERIPHERAL NEUROPATHY ELECTROPHYSIOLOGICAL SCREENING IN CHILDREN WITH CELIAC DISEASE

2015 ◽  
Vol 52 (2) ◽  
pp. 134-138 ◽  
Author(s):  
Şedat IŞIKAY ◽  
Nurgül IŞIKAY ◽  
Halil KOCAMAZ ◽  
Şamil HIZLI
Keyword(s):  
Nervous System ◽  
Celiac Disease ◽  
Peripheral Neuropathy ◽  
Peripheral Nervous System ◽  
Nerve Conduction ◽  
Sensory Nerve ◽  
Nerve Conduction Studies ◽  
Neurological Symptoms ◽  
Subclinical Neuropathy ◽  
Electrophysiological Studies

Background The involvement of the peripheral nervous system in children with celiac disease is particularly rare. Objective The aim of this study was to assess the need for neurophysiological testing in celiac disease patients without neurological symptoms in order to detect early subclinical neuropathy and its possible correlations with clinical and demographic characteristics. Methods Two hundred and twenty consecutive children with celiac disease were screened for neurological symptoms and signs, and those without symptoms or signs were included. Also, patients with comorbidities associated with peripheral neuropathy or a history of neurological disease were excluded. The remaining 167 asymptomatic patients as well as 100 control cases were tested electro-physiologically for peripheral nervous system diseases. Motor nerve conduction studies, including F-waves, were performed for the median, ulnar, peroneal, and tibial nerves, and sensory nerve conduction studies were performed for the median, ulnar, and sural nerves with H reflex of the soleus muscle unilaterally. All studies were carried out using surface recording electrodes. Normative values established in our laboratory were used. Results Evidence for subclinical neuropathy was not determined with electrophysiological studies in any of the participants. Conclusion In this highly selective celiac disease group without any signs, symptoms as well as the predisposing factors for polyneuropathy, we did not determine any cases with neuropathy. With these results we can conclude that in asymptomatic cases with celiac disease electrophysiological studies are not necessary. However, larger studies with the electrophysiological studies performed at different stages of disease at follow-ups are warranted.

Peripheral nervous system maturation in preterm infants: longitudinal motor and sensory nerve conduction studies

2018 ◽  
Vol 34 (6) ◽  
pp. 1145-1152 ◽  
Author(s):  
S. Lori ◽  
Giovanna Bertini ◽  
M. Bastianelli ◽  
S. Gabbanini ◽  
D. Gualandi ◽  
...  
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Preterm Infants ◽  
Nerve Conduction ◽  
Sensory Nerve ◽  
Nerve Conduction Studies

Electrophysiological Studies of Nerve Function in Patients on CAPD over Long Periods

1985 ◽  
Vol 5 (1) ◽  
pp. 45-48 ◽  
Author(s):  
Donald Kim ◽  
Gordon Blair ◽  
George Wu ◽  
Anthony Ayiomamitis ◽  
Dimitrios G. Oreopoulos
Keyword(s):  
Nerve Conduction ◽  
Motor Nerve ◽  
Linear Regression Analysis ◽  
Sensory Nerve ◽  
Diabetic Patients ◽  
Nerve Function ◽  
Mean Values ◽  
Conduction Velocities ◽  
Electrophysiological Studies ◽  
Peripheral Nerve Function

The authors studied electrophyhsiological parameters in 29 patients (23 non-diabetics, six diabetics, mean age 47.9, range 16–74 yr.), who had been on CAPD for three to five years. The parameters studied were: motor nerve conduction velocities of the median, ulnar, and peroneal nerves, and sensory nerve conduction velocities of the median and ulnar nerves. These parameters were measured before or within the first month of CAPD and every six months thereafter. The changes in nerve conduction velocities were studied using simple linear regression analysis, and calculating the differences of the slopes from zero. Comparison of the mean values of the conduction velocities in non-diabetics at the beginning of CAPD and in age - matched, non uremic patients showed significantly (p < 0.001) lower values in all parameters measured. The initial nerve conduction velocities in diabetic patients were significantly (p < 0.01) slower than in non-diabetics except sensory conduction velocity of the ulnar nerve. The slopes of nerve conduction velocities plotted against time were not significantly different from zero for any nerve in both non-diabetics and diabetic patients. In conclusion, no significant change in peripheral nerve function was seen after long term CAPD in either diabetic or non-diabetic patients.

Impairment Tutorial: Rating Sensory and Motor Deficits of the Upper Extremity

2000 ◽  
Vol 5 (2) ◽  
pp. 5-7
Author(s):  
Charles N. Brooks
Keyword(s):  
Nervous System ◽  
Evoked Potentials ◽  
Peripheral Nervous System ◽  
Conduction Velocity ◽  
Motor Neurons ◽  
Somatosensory Evoked Potentials ◽  
Nerve Conduction ◽  
Nerve Fibers ◽  
Nerve Conduction Studies ◽  
Electrical Potentials

Abstract The three components of electrodiagnosis useful in evaluation of the peripheral nervous system and spinal cord include electromyography (EMG), electroneurography (nerve conduction studies), and somatosensory evoked potentials. EMG examination involves introduction of a special recording needle into a muscle belly. Electrical potentials located within a few millimeters of the needle are picked up by an electrode and are transmitted from the muscle to amplifiers that filter and display results visually for the electromyographer. Three types of spontaneous activity in electrical potentials are of the greatest relevance: positive sharp waves, fibrillation potentials, and fasciculations (fasciculation potentials on the EMG result from irregular firing of motor units). Electromyography can help assess the status of nerve fibers indirectly, but the integrity of large myelinated sensory and motor neurons can be evaluated directly by nerve conduction studies (NCS), also known as electroneurography. NCS can assess motor neurons, sensory neurons, or mixed nerve trunks. Sensory nerve conduction velocity can be studied in a manner analogous to motor conduction velocity: sensory fibers can be directly stimulated, and the evoked response can be measured at the wrist and elbow. Somatosensory evoked potentials occasionally are useful as an adjunct to EMG and NCS in the diagnosis of peripheral nervous system pathology. These tests also are useful when it is unclear whether an individual has a true radiculopathy.

Electrodiagnosis of the Peripheral Nervous System: An Introduction

2014 ◽  
Vol 19 (3) ◽  
pp. 10-14
Author(s):  
Richard T. Katz
Keyword(s):  
Nervous System ◽  
Evoked Potentials ◽  
Spontaneous Activity ◽  
Peripheral Nervous System ◽  
Motor Neurons ◽  
Somatosensory Evoked Potentials ◽  
Nerve Conduction ◽  
Nerve Fibers ◽  
Nerve Conduction Studies ◽  
Mixed Nerve

Abstract This article is an introduction to electrodiagnosis of the peripheral nervous system, including electromyography, electroneurography (nerve conduction studies), and somatosensory evoked potentials. Electromyography involves the introduction of a special recording needle into a muscle body in search of spontaneous activity (electrical potentials that occur while the muscle is at rest). Three types of spontaneous activity are of greatest relevance: positive sharp waves, fibrillation potentials, and fasciculations. Electromyography can help assess the status of nerve fibers indirectly, but the integrity of large myelinated sensory and motor neurons can be evaluated directly by nerve conduction studies (NCS), also known as electroneurography. NCS involves the introduction of an electrical stimulus, either by surface electrode or needle, and recording an evoked response. NCS can assess motor neurons, sensory neurons, or mixed nerve trunks, depending on the strategy employed. Somatosensory evoked potentials (SSEP) sometimes are useful as an adjunct to EMG and NCS in the diagnosis of peripheral nervous system pathology and are obtained by stimulating a peripheral mixed nerve at a frequency of approximately 2-5 Hz. Several manufacturers have created automated, hand-held units for performing nerve conduction studies, and neuromuscular ultrasound is noninvasive and painless, and ultrasound of nerve entrapment has identified nerve enlargement just proximal to the site of entrapment. Physicians should know or learn the qualifications of the physician to whom they refer their patients for electrodiagnostic assessment.

P11.1 Peripheral nervous system maturation in very preterm infant: serial nerve conduction studies

2011 ◽  
Vol 122 ◽  
pp. S110
Author(s):  
E. Molesti ◽  
G. Bertini ◽  
D. Gualandi ◽  
C. Dani ◽  
M.E. Bastianelli ◽  
...  
Keyword(s):  
Nervous System ◽  
Preterm Infant ◽  
Peripheral Nervous System ◽  
Nerve Conduction ◽  
Nerve Conduction Studies ◽  
Very Preterm ◽  
Very Preterm Infant

Reproducibility of sensory nerve conduction studies of the sural nerve using ultrasound-guided needle positioning

2011 ◽  
Vol 44 (6) ◽  
pp. 873-876 ◽  
Author(s):  
Olivier Scheidegger ◽  
Alexander F. Küffer ◽  
Christian P. Kamm ◽  
Kai M. Rösler
Keyword(s):  
Nerve Conduction ◽  
Sural Nerve ◽  
Sensory Nerve ◽  
Nerve Conduction Studies ◽  
Ultrasound Guided

scholarly journals Carpal tunnel syndrome: long-term nerve conduction studies in 261 hands

2009 ◽  
Vol 67 (1) ◽  
pp. 69-73 ◽  
Author(s):  
Dante Guilherme Velasco Hardoim ◽  
Guilherme Bueno de Oliveira ◽  
João Aris Kouyoumdjian
Keyword(s):  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Nerve Conduction ◽  
Sensory Nerve ◽  
Nerve Conduction Studies ◽  
Sensory Nerve Action ◽  
Tunnel Syndrome ◽  
The Mean ◽  
Compound Action

OBJECTIVE: To compare a long-term carpal tunnel syndrome (CTS) on nerve conduction studies (NCS) in hands treated non-surgically. METHOD: We retrospectively selected 261 symptomatic CTS hands (166 patients), all of them confirmed by NCS. In all cases, at least 2 NCS were performed in an interval greater than 12 months. Cases with associated polyneuropathy were excluded. NCS parameters for CTS electrodiagnosis included a sensory conduction velocity (SCV) <46.6 m/s (wrist to index finger, 14 cm) and distal motor latency (DML) >4.25 ms (wrist to APB, 8 cm). RESULTS: 92.8% were women; mean age was 49 years (20-76); the mean interval between NCS was 47 months (12-150). In the first exam, the median sensory nerve action potential (SNAP) and the compound action muscular potential were absent in 9.8% and 1.9%, respectively. In the second/last exam, SCV worsened in 54.2%, remained unchanged in 11.6% and improved in 34.2%. SNAP amplitude worsened in 57.7%, remained unchanged in 13.1% and improved in 29.2%. DML worsened in 52.9%, remained unchanged in 7.6% and improved in 39.5%. Overall, NCS parameters worsened in 54.9%, improved in 34.3% and remained unchanged in 10.8%. CONCLUSION: Long-term changing in NCS of CTS hands apparently were not related to clinical symptomatology and could lead to some difficulty in clinical correlation and prognosis. Aging, male gender and absent SNAP were more related to NCS worsening, regardless the mean interval time between the NCS.

Sign in / Sign up

Export Citation Format

Share Document