A Pilot Study of Phenelzine in the Treatment of Post-traumatic Stress Disorder

1987 ◽  
Vol 150 (2) ◽  
pp. 252-255 ◽  
Author(s):  
Jonathan Davidson ◽  
J. Ingram Walker ◽  
Clinton Kilts
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Beta Blockers ◽  
Case Reports ◽  
Psychiatric Morbidity ◽  
Post Traumatic Stress ◽  
Combat Experience ◽  
Post Traumatic ◽  
Post Traumatic Disorder

In recent years, there has been renewed appreciation of the morbidity which can result from unusual or overwhelming stress and while many situations can give rise to post-traumatic disorder, the most frequently studied of these is probably military combat. Psychiatric disorder pursuant to combat experience can not only become chronic, but may intensify with advancing age, decades after the original trauma (Archibald & Tuddenbaum, 1965; Wilmer, 1982). Moreover, a high percentage of combat veterans are believed ultimately to develop chronic psychiatric morbidity (Walker & Cavenar, 1982). The drug treatment of such post-traumatic states remains an important question, largely over looked until the last 2 years but recent case reports suggest that doxepin and imipramine (White, 1983; Burstein, 1984) are beneficial in treating post traumatic stress disorder (PTSD), which may be either combat or non-combat related. Hogben & Cornfield (1981) described five veterans whose PTSD improved when treated with phenelzine, while Van der Kolk (1983) has described beneficial results with antidepressants, lithium, benzodiazepines, beta blockers, and neuroleptics in uncontrolled studies of PTSD.

scholarly journals Stigma, displacement stressors and psychiatric morbidity among displaced Syrian men who have sex with men (MSM) and transgender women: a cross-sectional study in Lebanon

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e046996
Author(s):  
Kirsty Clark ◽  
John Pachankis ◽  
Kaveh Khoshnood ◽  
Richard Bränström ◽  
David Seal ◽  
...  
Keyword(s):  
Mental Health ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Psychiatric Morbidity ◽  
Resource Scarcity ◽  
Transgender Women ◽  
Post Traumatic Stress ◽  
Post Traumatic ◽  
Sex With Men

BackgroundDisplaced Syrians face psychiatric morbidity often resulting from displacement-related stressors (eg, resource scarcity). Both men who have sex with men (MSM) and transgender women among the displaced Syrians are particularly vulnerable to mental health challenges given that they also often face stigma-related stressors (eg, discrimination).MethodsBetween January and December 2019 in greater Beirut, 258 Lebanese-born MSM and transgender women and 230 displaced Syrian MSM and transgender women were recruited via respondent-driven sampling to complete an in-person survey assessing displacement-related stressors, stigma-related stressors, depression, anxiety and post-traumatic stress disorder. In the total sample, we first documented the prevalence of psychiatric morbidity among the displaced Syrians; we then assessed associations among displacement-related and stigma-related stressors and each psychiatric outcome.ResultsSixty-three per cent of Syrian participants met criteria for depression compared with 43.8% of Lebanese participants (p<0.001); 21.3% of Syrians met criteria for severe anxiety compared with 13.1% of Lebanese participants (p<0.05) and 33.0% of Syrians met criteria for post-traumatic stress disorder compared with 18.4% of Lebanese participants (p<0.001). Among Syrian MSM and transgender women, sociodemographic characteristics, displacement-related stressors and stigma-related stressors were uniquely associated with psychiatric morbidity.ConclusionDisplaced Syrian MSM and transgender women experience higher levels of psychiatric comorbidities than Lebanese MSM and transgender women in part due to compounding exposure to displacement-related stressors and stigma-related stressors. Informed by tenets of minority stress theory and intersectionality theory, we discuss mental health intervention implications and future directions.

scholarly journals A Series of Case Reports Regarding the Use of Massage Therapy to Improve Sleep Quality in Individuals with Post-Traumatic Stress Disorder (PTSD)

2019 ◽  
Vol 12 (4) ◽  
pp. 3-9
Author(s):  
Bryn Sumpton, BScN ◽  
Amanda Baskwill, PhD, MSc, BEd, RMT
Keyword(s):  
Sleep Quality ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Case Reports ◽  
Massage Therapy ◽  
Poor Sleep ◽  
Post Traumatic Stress ◽  
Poor Sleep Quality ◽  
Post Traumatic

Background: Post-traumatic stress disorder (PTSD) is a common mental health diagnosis in Canada with prevalence estimated at about 2.4% in the general population. Previous studies have suggested massage therapy may be able to reduce the symptoms of PTSD. One of the symptoms commonly experienced is difficulty falling or staying asleep. No previously published massage therapy research has specifically assessed sleep symptoms of PTSD. Objectives: The research question was, “For individuals who have PTSD as a result of experiencing traumatic events, does MT have an effect on sleep quality?”Methods: A prospective series of case reports describing 10-week MT treatment plans provided by Registered Massage Therapists at Sutherland-Chan Clinic’s Belleville location. Three individuals with PTSD were recruited using promotional posters in the community. Treatment focused on improving sleep quality and followed a pragmatic treatment protocol using light to moderate pressure. Out-comes were measured using a sleep diary, Pittsburgh Sleep Quality Index, and the Leeds Sleep Evaluation Questionnaire. Results: Data collected at baseline and throughout the series showed inconsistent improvement and worsening of symptoms amongst participants. Treatment was well tolerated and attended. No harmful incidents were noted. Conclusion: For these participants, MT did not predictably impact sleep quality. It is possible, as the underlying cause of poor sleep quality was unlikely resolved, the participants did not have a significant change in their sleep quality. This differs from findings of previous studies in which MT improved sleep for patients with poor sleep quality due to exposure to traumatic events. There is need for further understanding of how MT affects sleep. 

scholarly journals Late-onset secondary nocturnal enuresis in adolescents associated with post-traumatic stress disorder developed after a traffic accident

2015 ◽  
Vol 87 (3) ◽  
pp. 250 ◽  
Author(s):  
Serkan Akan ◽  
Ahmet Ürkmez ◽  
Caglar Yildirim ◽  
Aytac Sahin ◽  
Özgür Haki Yüksel ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Nocturnal Enuresis ◽  
Traffic Accident ◽  
Stress Disorder ◽  
Late Onset ◽  
Case Reports ◽  
Post Traumatic Stress ◽  
Post Traumatic

Secondary nocturnal enuresis is generally seen between 5 and 7 years of age and it is rarely encountered when compared with the primary incontinence. Patients with suggested diagnosis of secondary nocturnal enuresis should be examined for neurological and spinal anomalies and diabetes mellitus, diabetes insipidus, renal failure and urinary tract infection should be ruled out in differential diagnosis (1-3). Herein, we are presenting case reports of adolescent patients with secondary nocturnal enuresis refractory to medical therapy and developed after in-vehicle and extravehicular accidents.

scholarly journals Predictors of post-traumatic stress disorder following physical trauma: an examination of the stressor criterion

1991 ◽  
Vol 21 (1) ◽  
pp. 85-91 ◽  
Author(s):  
Anthony Feinstein ◽  
Ray Dolan
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Traumatic Event ◽  
Psychiatric Morbidity ◽  
Post Traumatic Stress ◽  
Event Scale ◽  
Physical Trauma ◽  
Post Traumatic ◽  
The Impact

SYNOPSISA prospective study documenting psychopathology was undertaken in 48 subjects exposed to a range of physical trauma, but whose injuries were of similar severity. No support was found for the DSM-III-R view correlating the severity of the stressor with the development of post-traumatic stress disorder (PTSD). Distress post injury (high scores on the impact of event scale), indicative of difficulty with cognitive assimilation of the traumatic event, was found to be highly predictive of psychiatric morbidity and PTSD at 6 months.

Post-traumatic stress disorder and depression

1997 ◽  
Vol 170 (5) ◽  
pp. 479-482 ◽  
Author(s):  
Avi Bleich ◽  
Meni Koslowsky ◽  
Aliza Dolev ◽  
Bernard Lerer
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Affective Disorders ◽  
Stress Disorder ◽  
Psychiatric Morbidity ◽  
War Trauma ◽  
Drug Misuse ◽  
Special Focus ◽  
Post Traumatic Stress ◽  
Post Traumatic

BackgroundWe examined psychiatric morbidity following war-related psychic trauma, with a special focus on the depressive comorbidity of post-traumatic stress disorder (PTSD).MethodSubjects consisted of 60 Israeli veterans who sought psychiatric treatment 4–6 years after having been exposed to war trauma. PTSD and psychiatric comorbidity were diagnosed using the Structured Interview for PTSD and the Schedule for Affective Disorders and Schizophrenia.ResultsBoth lifetime (100%) and current (87%) PTSD were the most prevalent disorders. Comorbidity was extensive, with major depressive disorder (MDD) most prevalent (95% lifetime, 50% current), followed by anxiety disorders, minor affective disorders, and alcoholism or drug misuse.ConclusionsWithin post-traumatic psychiatric morbidity of combat origin, PTSD and MDD are the most prevalent disorders. In addition it appears that PTSD, although related to post-traumatic MDD beyond a mere sharing of common symptoms, is of the same time differentiated from it as an independent diagnostic category.

Psychiatric Morbidity in Survivors of Organised State Violence Including Torture

1993 ◽  
Vol 162 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Rosalind Ramsay ◽  
Caroline Gorst-Unsworth ◽  
Stuart Turner
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Somatoform Disorders ◽  
Psychiatric Morbidity ◽  
Well Being ◽  
State Violence ◽  
Post Traumatic Stress ◽  
Post Traumatic ◽  
Survivors Of Torture

The case notes documenting the psychological well-being of 100 survivors of torture and other forms of organised state violence were analysed retrospectively. The most common diagnoses were post-traumatic stress disorder (PTSD), major depression, and somatoform disorders. Of these, PTSD showed the strongest association with experience of torture. It is possible that PTSD has a dimensional nature, and that reactions to different stressors are heterogeneous.

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