Bipolar Disorder in Post-traumatic Stress Disorder—A Difficult Diagnosis: Case Reports

1986 ◽  
Vol 151 (5) ◽  
pp. 282-284 ◽  
Author(s):  
Robert G. Lucking
1987 ◽  
Vol 150 (2) ◽  
pp. 252-255 ◽  
Author(s):  
Jonathan Davidson ◽  
J. Ingram Walker ◽  
Clinton Kilts

In recent years, there has been renewed appreciation of the morbidity which can result from unusual or overwhelming stress and while many situations can give rise to post-traumatic disorder, the most frequently studied of these is probably military combat. Psychiatric disorder pursuant to combat experience can not only become chronic, but may intensify with advancing age, decades after the original trauma (Archibald & Tuddenbaum, 1965; Wilmer, 1982). Moreover, a high percentage of combat veterans are believed ultimately to develop chronic psychiatric morbidity (Walker & Cavenar, 1982). The drug treatment of such post-traumatic states remains an important question, largely over looked until the last 2 years but recent case reports suggest that doxepin and imipramine (White, 1983; Burstein, 1984) are beneficial in treating post traumatic stress disorder (PTSD), which may be either combat or non-combat related. Hogben & Cornfield (1981) described five veterans whose PTSD improved when treated with phenelzine, while Van der Kolk (1983) has described beneficial results with antidepressants, lithium, benzodiazepines, beta blockers, and neuroleptics in uncontrolled studies of PTSD.


2019 ◽  
Vol 15 (2) ◽  
pp. 116-131
Author(s):  
Stephanie Laird ◽  
Luke J. Ney ◽  
Kim L. Felmingham ◽  
Andrea Gogos

Background: The combined oral contraceptive pill (OC), containing synthetic estrogens and progestins, is used by millions of women worldwide, yet little is known about its effects on cognition or on psychiatric disorders. The progestin component of OCs determines their androgenicity, i.e. whether the OC has androgen binding components with masculinising effects or antiandrogenic components with feminising effects. Objective: The present review discusses the literature surrounding OC use and cognition in healthy women. Given the important role that sex hormones play in psychiatric disorders, we also consider the influence of OCs on symptoms of schizophrenia, post-traumatic stress disorder, depression, bipolar disorder, anxiety disorders and indirectly, sleep quality. Results: Research has shown that while there are no differences between OC users and non-users, androgenic OCs enhance visuospatial ability and anti-androgenic OCs enhance verbal fluency. Little is known about OCs effects on other cognitive domains, such as memory and executive function. There is little research examining OC use in schizophrenia, post-traumatic stress disorder, bipolar disorder and anxiety disorders. There is some evidence that OC use is associated with depression, however the exact causality of this association remains to be verified. Conclusion: We maintain that future studies need to address several methodological limitations, such as separating OCs based on androgenicity to avoid the masking effects that occur when various OCs are considered as one group. As this review highlights several significant effects of OC use on the brain, the implications of OC use needs to be considered in future research.


2019 ◽  
Vol 176 (21) ◽  
pp. 4119-4135 ◽  
Author(s):  
Andrea Gogos ◽  
Luke J. Ney ◽  
Natasha Seymour ◽  
Tamsyn E. Van Rheenen ◽  
Kim L. Felmingham

2016 ◽  
Vol 21 (4) ◽  
pp. 621-632 ◽  
Author(s):  
Julia M. Carter ◽  
Timothy J. Arentsen ◽  
Matthew J. Cordova ◽  
Josef Ruzek ◽  
Robert Reiser ◽  
...  

2014 ◽  
Vol 179 (2) ◽  
pp. 157-161 ◽  
Author(s):  
Robert N. McLay ◽  
Vasudha Ram ◽  
Jennifer Webb-Murphy ◽  
Alicia Baird ◽  
Anita Hickey ◽  
...  

Author(s):  
Bryn Sumpton, BScN ◽  
Amanda Baskwill, PhD, MSc, BEd, RMT

Background: Post-traumatic stress disorder (PTSD) is a common mental health diagnosis in Canada with prevalence estimated at about 2.4% in the general population. Previous studies have suggested massage therapy may be able to reduce the symptoms of PTSD. One of the symptoms commonly experienced is difficulty falling or staying asleep. No previously published massage therapy research has specifically assessed sleep symptoms of PTSD. Objectives: The research question was, “For individuals who have PTSD as a result of experiencing traumatic events, does MT have an effect on sleep quality?”Methods: A prospective series of case reports describing 10-week MT treatment plans provided by Registered Massage Therapists at Sutherland-Chan Clinic’s Belleville location. Three individuals with PTSD were recruited using promotional posters in the community. Treatment focused on improving sleep quality and followed a pragmatic treatment protocol using light to moderate pressure. Out-comes were measured using a sleep diary, Pittsburgh Sleep Quality Index, and the Leeds Sleep Evaluation Questionnaire. Results: Data collected at baseline and throughout the series showed inconsistent improvement and worsening of symptoms amongst participants. Treatment was well tolerated and attended. No harmful incidents were noted. Conclusion: For these participants, MT did not predictably impact sleep quality. It is possible, as the underlying cause of poor sleep quality was unlikely resolved, the participants did not have a significant change in their sleep quality. This differs from findings of previous studies in which MT improved sleep for patients with poor sleep quality due to exposure to traumatic events. There is need for further understanding of how MT affects sleep. 


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