Alkali Reserve in Progressive General Paralysis Before and After Malaria Therapy. (Bull. Acad. Med., vol. cxiv, pp. 436–40, 1935.) Paulian, D., and Tanasesco, G.

1937 ◽  
Vol 83 (342) ◽  
pp. 124-124
Author(s):  
A. E. Meyer
1893 ◽  
Vol 39 (166) ◽  
pp. 355-367 ◽  
Author(s):  
J. Wiglesworth

We are in the habit of regarding general paralysis as in the main a disease of the prime of life—of a time when the fresh vigour of youth has subsided, but before the first touch of decay has laid its hand upon the organism; when the mental faculties are strained to the utmost in the pursuit of wealth or pleasure, or social distinction, or in the keen struggle for existence entailed upon so many of our race. We are not indeed unaccustomed to meet with cases of this disease occurring both before and after this epoch of life, but the association of general paralysis with the period of childhood and puberty has hitherto been a very unfamiliar idea. Nevertheless, scattered cases have from time to time been published which tend to show that the period of life which appears to offer most exemption from all the ordinary causes of the disease may still claim its victims, and that at, or about, the period of puberty cases may occur which, both clinically and pathologically, appear incapable of separation from the ordinary forms of the disease with which we are so familiar.


BMJ ◽  
1941 ◽  
Vol 1 (4178) ◽  
pp. 174-174
Author(s):  
C. A. Gill

1924 ◽  
Vol 70 (288) ◽  
pp. 81-89 ◽  
Author(s):  
A. R. Grant ◽  
J. D. Silverston

In the early part of 1922 our attention was drawn to the excellent results claimed by Wagner-Jauregg (1), Gerstmann (2), Weygandt (3) and others in the treatment of general paralysis by the inoculation of malaria. Since July 31, 1922, over fifty general paralytics have been subjected to this form of fever therapy, and in this contribution we propose to give a brief summary of our observations and com elusions.


The Lancet ◽  
1924 ◽  
Vol 203 (5246) ◽  
pp. 540-543 ◽  
Author(s):  
A.R. Grant ◽  
J.D. Silverston

1929 ◽  
Vol 25 (7-8) ◽  
pp. 968-969
Author(s):  
S. Esselevich

Sigfried Hecht is trying to approach the solution of the problem, about changing the pictures of symptoms and the course of p. R. before and after the introduction of malaria therapy; cites comparative statistical data of other researchers, as well as his own, obtained by him on hospital material in 1920-23.


2020 ◽  
Vol 31 (3) ◽  
pp. 325-340
Author(s):  
Olga Villasante

This article addresses the implementation of malaria fever therapy in Spain. Neuropsychiatrist Rodríguez-Lafora first used it in 1924, but Vallejo-Nágera was the main advocate for the technique. He had learned the method from Wagner von Jauregg himself, and he worked in the Military Psychiatric Clinic and the San José Mental Hospital, both in Ciempozuelos (Madrid). Vallejo-Nágera worked with the parasitologist Zozaya, who had travelled to England with a Rockefeller Foundation grant in order to learn from British malariologist, Sydney Price James. This article details the results of the uneven implementation of this treatment in Spanish psychiatric institutions. Although syphilologists and internists used fever therapy for the treatment of general paralysis of the insane, they were much less enthusiastic than psychiatrists.


Author(s):  
J. Temple Black

Tool materials used in ultramicrotomy are glass, developed by Latta and Hartmann (1) and diamond, introduced by Fernandez-Moran (2). While diamonds produce more good sections per knife edge than glass, they are expensive; require careful mounting and handling; and are time consuming to clean before and after usage, purchase from vendors (3-6 months waiting time), and regrind. Glass offers an easily accessible, inexpensive material ($0.04 per knife) with very high compressive strength (3) that can be employed in microtomy of metals (4) as well as biological materials. When the orthogonal machining process is being studied, glass offers additional advantages. Sections of metal or plastic can be dried down on the rake face, coated with Au-Pd, and examined directly in the SEM with no additional handling (5). Figure 1 shows aluminum chips microtomed with a 75° glass knife at a cutting speed of 1 mm/sec with a depth of cut of 1000 Å lying on the rake face of the knife.


Author(s):  
R. F. Bils ◽  
W. F. Diller ◽  
F. Huth

Phosgene still plays an important role as a toxic substance in the chemical industry. Thiess (1968) recently reported observations on numerous cases of phosgene poisoning. A serious difficulty in the clinical handling of phosgene poisoning cases is a relatively long latent period, up to 12 hours, with no obvious signs of severity. At about 12 hours heavy lung edema appears suddenly, however changes can be seen in routine X-rays taken after only a few hours' exposure (Diller et al., 1969). This study was undertaken to correlate these early changes seen by the roengenologist with morphological alterations in the lungs seen in the'light and electron microscopes.Forty-two adult male and female Beagle dogs were selected for these exposure experiments. Treated animals were exposed to 94.5-107-5 ppm phosgene for 10 min. in a 15 m3 chamber. Roentgenograms were made of the thorax of each animal before and after exposure, up to 24 hrs.


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