Liquid Chromatography/Electrochemistry in Pharmaceutical Analysis

Method transfer for fast liquid chromatography in pharmaceutical analysis: Application to short columns packed with small particle. Part I: Isocratic separation

European Journal of Pharmaceutics and Biopharmaceutics ◽

10.1016/j.ejpb.2006.11.027 ◽

2007 ◽

Vol 66 (3) ◽

pp. 475-482 ◽

Cited By ~ 88

Author(s):

Davy Guillarme ◽

Dao T.-T. Nguyen ◽

Serge Rudaz ◽

Jean-Luc Veuthey

Keyword(s):

Liquid Chromatography ◽

Small Particle ◽

Pharmaceutical Analysis ◽

Method Transfer ◽

Short Columns ◽

Analysis Application ◽

Fast Liquid Chromatography

Two-Dimensional Liquid Chromatography (2D-LC) in Pharmaceutical Analysis: Applications Beyond Increasing Peak Capacity

Chromatographia ◽

10.1007/s10337-018-3474-8 ◽

2018 ◽

Vol 81 (3) ◽

pp. 401-418 ◽

Cited By ~ 8

Author(s):

Imad A. Haidar Ahmad ◽

Andrei Blasko ◽

Adrian Clarke ◽

Shereen Fakih

Keyword(s):

Liquid Chromatography ◽

Pharmaceutical Analysis ◽

Peak Capacity ◽

Two Dimensional

Quality by Design as a risk-based strategy in pharmaceutical analysis: Development of a liquid chromatography-tandem mass spectrometry method for the determination of nintedanib and its impurities

Journal of Chromatography A ◽

10.1016/j.chroma.2019.460615 ◽

2020 ◽

Vol 1611 ◽

pp. 460615

Author(s):

Benedetta Pasquini ◽

Serena Orlandini ◽

Sandra Furlanetto ◽

Roberto Gotti ◽

Massimo Del Bubba ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Pharmaceutical Analysis ◽

Quality By Design ◽

Tandem Mass ◽

Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Method transfer for fast liquid chromatography in pharmaceutical analysis: Application to short columns packed with small particle. Part II: Gradient experiments

European Journal of Pharmaceutics and Biopharmaceutics ◽

10.1016/j.ejpb.2007.06.018 ◽

2008 ◽

Vol 68 (2) ◽

pp. 430-440 ◽

Cited By ~ 128

Author(s):

Davy Guillarme ◽

Dao T.T. Nguyen ◽

Serge Rudaz ◽

Jean-Luc Veuthey

Keyword(s):

Liquid Chromatography ◽

Small Particle ◽

Pharmaceutical Analysis ◽

Method Transfer ◽

Short Columns ◽

Analysis Application ◽

Fast Liquid Chromatography

Model building for the prediction of initial chromatographic conditions in pharmaceutical analysis using reversed-phase liquid chromatography

Journal of Chromatography A ◽

10.1016/0021-9673(93)83136-g ◽

1993 ◽

Vol 633 (1-2) ◽

pp. 43-56 ◽

Cited By ~ 15

Author(s):

T. Hamoir ◽

B. Bourguignon ◽

D.L. Massart ◽

H. Hindriks

Keyword(s):

Liquid Chromatography ◽

Pharmaceutical Analysis ◽

Model Building ◽

Reversed Phase ◽

Reversed Phase Liquid Chromatography ◽

Phase Liquid

Liquid Chromatography in Pharmaceutical Analysis IV: Determination of Antispasmodic Mixtures

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600640829 ◽

1975 ◽

Vol 64 (8) ◽

pp. 1389-1393 ◽

Cited By ~ 15

Author(s):

I.L. Honigberg ◽

J.T. Stewart ◽

A.P. Smith ◽

R.D. Plunkett ◽

E.L. Justice

Keyword(s):

Liquid Chromatography ◽

Pharmaceutical Analysis

Validation of analytical procedures by high−performance liquid chromatography for pharmaceutical analysis

Chromatography ◽

10.15583/jpchrom.2012.005 ◽

2012 ◽

Vol 33 (2) ◽

pp. 65-73 ◽

Cited By ~ 8

Author(s):

Masato Kazusaki ◽

Shinji Ueda ◽

Naoto Takeuchi ◽

Yasutaka Ohgami

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Pharmaceutical Analysis ◽

High Performance ◽

Analytical Procedures

Importance of instrumentation for fast liquid chromatography in pharmaceutical analysis

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2013.03.012 ◽

2014 ◽

Vol 87 ◽

pp. 105-119 ◽

Cited By ~ 87

Author(s):

Szabolcs Fekete ◽

Isabelle Kohler ◽

Serge Rudaz ◽

Davy Guillarme

Keyword(s):

Liquid Chromatography ◽

Pharmaceutical Analysis ◽

Fast Liquid Chromatography

Liquid Chromatography in Pharmaceutical Analysis XI: Determination of Muscle Relaxant-Analgesic Mixtures Using Reversed-Phase and Ion-Pair Techniques

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600680112 ◽

1979 ◽

Vol 68 (1) ◽

pp. 32-36 ◽

Cited By ~ 23

Author(s):

J.T. Stewart ◽

I.L. Honigberg ◽

J.W. Coldren

Keyword(s):

Liquid Chromatography ◽

Muscle Relaxant ◽

Pharmaceutical Analysis ◽

Reversed Phase ◽

Ion Pair

Recent Trends in Chiral Separation-A Collective Paradigm of Selected Chiral Impurities

Current Pharmaceutical Analysis ◽

10.2174/1573412915666181219144507 ◽

2020 ◽

Vol 16 (5) ◽

pp. 456-473

Author(s):

Prachi Raikar ◽

Gurupadayya Bannimath

Keyword(s):

Gas Chromatography ◽

High Performance Liquid Chromatography ◽

Capillary Electrophoresis ◽

Liquid Chromatography ◽

Adverse Effects ◽

Chiral Separation ◽

Pharmaceutical Analysis ◽

High Performance ◽

Ich Guidelines ◽

Recent Trends

Chiral separation plays a very important role in the modern pharmaceutical analysis and will continue in upcoming years. Separation and identification of chiral impurities are indispensable. According to ICH guidelines, only the active enantiomer of the drug has to be marketed, so there is a focus on separation of the inactive enantiomer which acts as a chiral impurity. The impurities present in the enantiomers also pose various toxic adverse effects on bioavailability and efficacy, hence the need to separate these impurities will forever be trending. This review primarily focuses on the separation techniques like Capillary Electrophoresis (CE), High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), and Supercritical Fluid Chromatography (SFC) followed by the year-wise trend in the separation of selected chiral impurities. In the coming years, researchers should work on using ultra-fast, selective, and sensitive methods for the effective separation of chiral impurities.