Mitochondrial Genetics of Saccharomyces cerevisiae

2020 ◽  
pp. 247-257
Author(s):  
Klaus Wolf
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Mitochondrial Genetics

scholarly journals MITOCHONDRIAL GENETICS. VI THE PETITE MUTATION IN SACCHAROMYCES CEREVISIAE: INTERRELATIONS BETWEEN THE LOSS OF THE ρ+ FACTOR AND THE LOSS OF THE DRUG RESISTANCE MITOCHONDRIAL GENETIC MARKERS

Genetics ◽  
1974 ◽  
Vol 76 (2) ◽  
pp. 195-219
Author(s):  
J Deutsch ◽  
B Dujon ◽  
P Netter ◽  
E Petrochilo ◽  
P P Slonimski ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Drug Resistance ◽  
Mitochondrial Genome ◽  
Genetic Marker ◽  
Genetic Markers ◽  
The Other ◽  
Mitochondrial Genetics ◽  
Petite Mutation ◽  
Target Theory

ABSTRACT The survival of the ρ+ factor and of DrugR mitochondrial genetic markers after exposure to ethidium bromide has been studied. A technique allowing the determination of DrugR genetic markers among a great number of both grande and petite colonies has been developed. The results have been analyzed by the target theory. The survival of the ρ+ factor is always less than the survival of any DrugR genetic marker. The survivals of CR and ER are similar to each other, while that of OR is greater than that of the other two DrugR markers. All possible combinations of DrugR markers have been found among the ρ- petite cells induced, while the only type found among the grande colonies is the preexisting one. The loss of the CR and ER genetic markers was found to be the most frequently concomitant, while the correlation between the loss of the OR marker and the other two DrugR markers is less strong. Similar results have been obtained after U.V. irradiation. Interpretations concerning the structure of the yeast mitochondrial genome are given and hypotheses on the mechanism of petite mutation discussed.

scholarly journals Mitochondrial genetics, circular DNA and the mechanism of thepetitemutation in yeast

1974 ◽  
Vol 24 (1) ◽  
pp. 43-57 ◽  
Author(s):  
G. D. Clark-Walker ◽  
George L. Gabor Miklos
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Structural Rearrangements ◽  
Dna Molecules ◽  
Mitochondrial Genetics ◽  
General Hypothesis ◽  
Mitochondrial Recombination ◽  
Circular Dna ◽  
Bacterial Plasmids ◽  
Circular Dnas

SUMMARYWe propose a general hypothesis involving properties of circular DNA which can explain such phenomena as thepetitemutation, suppressiveness, and the polarity observed in mitochondrial recombination in the yeastSaccharomyces cerevisiae. This hypothesis involves excision and insertion events between circular DNA molecules as well as structural rearrangements in the DNA generated by these events. The special properties of circular DNA have been considered in analysing recombination, and a number of results are obtained which are not intuitively apparent.This hypothesis can be applied to any situation involving circular DNA such as bacterial plasmids and cytoplasmic circular DNAs, where the opportunity exists for recombination and rearrangement events.

Mitochondrial genetics X: Effects of UV irradiation on transmission and recombination of mitochondrial genes in Saccharomyces cerevisiae

1975 ◽  
Vol 137 (1) ◽  
pp. 29-72 ◽  
Author(s):  
B. Dujon ◽  
A. Kruszewska ◽  
P. P. Slonimski ◽  
M. Bolotin-Fukuhara ◽  
D. Coen ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Uv Irradiation ◽  
Mitochondrial Genes ◽  
Mitochondrial Genetics

Anti-Saccharomyces cerevisiae Antibodies in Inflammatory Bowel Disease: a Family Study

2001 ◽  
Vol 36 (2) ◽  
pp. 196-201 ◽  
Author(s):  
F. Seibold ◽  
O. Stich ◽  
R. Hufnagl ◽  
S. Kamil ◽  
M. Scheurlen
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Family Study ◽  
Inflammatory Bowel

Immunreaktion auf Saccharomyces cerevisiae Antigene in Patienten mit Morbus Crohn

2007 ◽  
Vol 45 (08) ◽  
Author(s):  
S Schmechel ◽  
V Schachinger ◽  
F Seibold ◽  
C Tillack ◽  
T Ochsenkühn ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Morbus Crohn
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