Objectively forecasting the runout of a potential open pit slope failure, in addition to identifying the failure itself, is a critical component of a mine’s risk management plan. Recent losses arising from large open pit slope failures demonstrate shortcomings in current practice. A dataset of 105 pit slope failures was compiled to compare open pit runout trends against established empirical runout relationships for natural landslides. Fahrböschung angle versus volume and Fahrböschung angle versus slope angle relationships provide reasonable runout estimates. Open pit slopes have the advantage of removing the influence of morphological features, vegetation, and liquefiable substrates while controlling the travel path angle and roughness. In such a controlled environment, landslide mobility has a strong sensitivity to slope angle, material properties, and fall height, and is only modestly sensitive to volume. A grouping of highly mobile open pit slope cases involving weathered, saturated, collapsible rock mass materials exceed expected runout distances when compared with established runout trends. This suggests mobility for these weaker rock masses is controlled by pore pressures mediating basal friction. The result is that two different runout exceedance trends are observed based on whether the unstable rock mass involves fresh, strong rocks or weathered weak rocks.