The rapid development of drug nanocarriers has benefited from surface hydrophilic polymers of particles, which has improved the drug's pharmacokinetics. Polyethylene glycol (PEG) is a kind of polymeric material with...
Liposomal formulations were significantly explored over the last decade for the ophthalmic drug delivery applications. These formulations are mainly composed of phosphatidylcholine (PC) and other constituents such as cholesterol and lipid-conjugated hydrophilic polymers. Liposomes are biodegradable and biocompatible in nature. Current approaches for topical delivery of liposomes are focused on improving the corneal adhesion and permeation by incorporating various bioadhesive and penetration enhancing polymers. In the case of posterior segment disorders improvement in intravitreal half life and targeted drug delivery to the retina is achieved by liposomes. In this paper we have attempted to summarize the applications of liposomes in the field of ophthalmic drug delivery by citing numerous investigators over the last decade.
Roles of Polyethylene Glycol on the Surface of Nanoparticles for Targeted Drug Delivery
