Development of Radiotracers and Fluorescent Probes for Imaging Sigma-2 Receptors In Vitro and In Vivo

2012 ◽  
pp. 281-296
Keyword(s):  
2020 ◽  
Vol 39 (1) ◽  
pp. 209-221
Author(s):  
Jiafeng Wan ◽  
Xiaoyuan Zhang ◽  
Kai Zhang ◽  
Zhiqiang Su

Abstract In recent years, nanomaterials have attracted lots of attention from researchers due to their unique properties. Nanometer fluorescent materials, such as organic dyes, semiconductor quantum dots (QDs), metal nano-clusters (MNCs), carbon dots (CDs), etc., are widely used in biological imaging due to their high sensitivity, short response time, and excellent accuracy. Nanometer fluorescent probes can not only perform in vitro imaging of organisms but also achieve in vivo imaging. This provides medical staff with great convenience in cancer treatment. Combined with contemporary medical methods, faster and more effective treatment of cancer is achievable. This article explains the response mechanism of three-nanometer fluorescent probes: the principle of induced electron transfer (PET), the principle of fluorescence resonance energy transfer (FRET), and the principle of intramolecular charge transfer (ICT), showing the semiconductor QDs, precious MNCs, and CDs. The excellent performance of the three kinds of nano fluorescent materials in biological imaging is highlighted, and the application of these three kinds of nano fluorescent probes in targeted biological imaging is also introduced. Nanometer fluorescent materials will show their significance in the field of biomedicine.


Biomaterials ◽  
2018 ◽  
Vol 159 ◽  
pp. 82-90 ◽  
Author(s):  
Feiyi Wang ◽  
Ge Xu ◽  
Xianfeng Gu ◽  
Zhijun Wang ◽  
Zhiqiang Wang ◽  
...  

2016 ◽  
Vol 88 (3) ◽  
pp. 1944-1950 ◽  
Author(s):  
Hualong Fu ◽  
Peiyu Tu ◽  
Liu Zhao ◽  
Jiapei Dai ◽  
Boli Liu ◽  
...  

2018 ◽  
Vol 16 (2) ◽  
pp. 164-168 ◽  
Author(s):  
Bahareh Shirinfar ◽  
Humaira Seema ◽  
Nisar Ahmed
Keyword(s):  

Imidazolium-based charged fluorescent probes for the selective in vitro and in vivo recognition of RNA over other biomolecules.


Nano Reviews ◽  
2010 ◽  
Vol 1 (1) ◽  
pp. 5161 ◽  
Author(s):  
Sarwat B. Rizvi ◽  
Shirin Ghaderi ◽  
Mo Keshtgar ◽  
Alexander M. Seifalian

2020 ◽  
Vol 56 (56) ◽  
pp. 7718-7721 ◽  
Author(s):  
Linfang Wang ◽  
Jing Liu ◽  
Shengwei Zhao ◽  
Hongxing Zhang ◽  
Yuanqiang Sun ◽  
...  

Hydro-Si-oxazines were exploited as NIR fluorescent probes to monitor HClO/ONOO− produced by phagocytes in inflammation-related diseases.


2009 ◽  
Vol 6 (2) ◽  
pp. 416-427 ◽  
Author(s):  
Zongren Zhang ◽  
Jinda Fan ◽  
Philip P. Cheney ◽  
Mikhail Y. Berezin ◽  
W. Barry Edwards ◽  
...  

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